Results 21 to 30 of about 846,213 (256)

M1/M2 Macrophage Polarity in Normal and Complicated Pregnancy [PDF]

Frontiers in Immunology, 2014
Tissue macrophages play an important role in all stages of pregnancy, including uterine stromal remodeling (decidualization) before embryo implantation, parturition, and post-partum uterine involution. The activation state and function of utero-placental macrophages are largely dependent on the local tissue microenvironment.
Brown, Mary B., von Chamier, Maria, Allam, Ayman B., Reyes, Leticia   +3 more
openaire   +3 more sources

Microglial M1/M2 polarization and metabolic states [PDF]

British Journal of Pharmacology, 2015
Microglia are critical nervous system‐specific immune cells serving as tissue‐resident macrophages influencing brain development, maintenance of the neural environment, response to injury and repair. As influenced by their environment, microglia assume a diversity of phenotypes and retain the capability to shift functions to maintain tissue homeostasis.
Ruben, Orihuela, Christopher A, McPherson, Gaylia Jean, Harry   +2 more
openaire   +2 more sources

LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization [PDF]

Cancer Immunology Research, 2019
Abstract M2 polarization of macrophages is essential for their function in immunologic tolerance, which might promote tumorigenesis. However, the molecular mechanism behind the polarization process is not fully understood. Given that several lines of evidence have suggested that long noncoding RNAs (lncRNAs) could be involved in ...
Ji, Cao, Rong, Dong, Li, Jiang, Yanling, Gong, Meng, Yuan, Jieqiong, You, Wen, Meng, Zhanlei, Chen, Ning, Zhang, Qinjie, Weng, Hong, Zhu, Qiaojun, He, Meidan, Ying, Bo, Yang   +13 more
openaire   +2 more sources

CD73 Activity is Dispensable for the Polarization of M2 Macrophages

PLOS ONE, 2015
The ectoenzyme CD73 catalyzes the hydrolysis of AMP, and is one of the most important producers of extracellular adenosine. On regulatory T cells, CD73 is necessary for immunosuppressive functions, and on Th17 cells CD73-generated adenosine exerts anti-inflammatory effects.
Eichin Dominik, Laurila Juha Petteri, Salmi Marko Henrikki, Jalkanen Sirpa Tuulikki   +3 more
openaire   +5 more sources

A unique role for p53 in the regulation of M2 macrophage polarization [PDF]

Cell Death & Differentiation, 2014
P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased when macrophages are polarized to the M2 (alternatively activated macrophage ...
L Li, D S W Ng, W-C Mah, F F Almeida, S A Rahmat, V K Rao, S C Leow, F Laudisi, M T Peh, A M Goh, J S Y Lim, G D Wright, A Mortellaro, R Taneja, F Ginhoux, C G Lee, P K Moore, D P Lane   +17 more
openaire   +2 more sources

Exosomal DLX6-AS1 from hepatocellular carcinoma cells induces M2 macrophage polarization to promote migration and invasion in hepatocellular carcinoma through microRNA-15a-5p/CXCL17 axis

Journal of Experimental & Clinical Cancer Research, 2021
Background Hepatocellular carcinoma (HCC) cells-secreted exosomes (exo) could stimulate M2 macrophage polarization and promote HCC progression, but the related mechanism of long non-coding RNA distal-less homeobox 6 antisense 1 (DLX6-AS1) with HCC-exo ...
Lin-pei Wang, Jing Lin, Xiao-qiu Ma, Dong-yao Xu, Chun-feng Shi, Wei Wang, Xiao-jie Jiang   +6 more
doaj   +1 more source

Arsenic Induces M2 Macrophage Polarization and Shifts M1/M2 Cytokine Production via Mitophagy

International Journal of Molecular Sciences, 2022
Arsenic is an environmental factor associated with epithelial–mesenchymal transition (EMT). Since macrophages play a crucial role in regulating EMT, we studied the effects of arsenic on macrophage polarization. We first determined the arsenic concentrations to be used by cell viability assays in conjunction with previous studies.
Chih-Hsing Hung, Hua-Yu Hsu, Hsin-Ying Clair Chiou, Mei-Lan Tsai, Huey-Ling You, Yu-Chih Lin, Wei-Ting Liao, Yi-Ching Lin   +7 more
openaire   +2 more sources

M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment

Neural Plasticity, 2019
Atherosclerosis is a chronic progressive inflammation course, which could induce life-threatening diseases such as stroke and myocardial infarction.
Ying Bi, Jixiang Chen, Feng Hu, Jing Liu, Man Li, Lei Zhao   +5 more
doaj   +1 more source

Different macrophage polarization between drug-susceptible and multidrug-resistant pulmonary tuberculosis

BMC Infectious Diseases, 2020
Background Macrophages play a key role in the infection process, and alternatively activated macrophages (M2 polarization) play important roles in persistent infection via the immune escape of pathogens. This suggests that immune escape of pathogens from
Hyun Jin Cho, Yun-Ji Lim, Jhingook Kim, Won-Jung Koh, Chang-Hwa Song, Min-Woong Kang   +5 more
doaj   +1 more source

Reconfigurable beams with arbitrary polarization and shape distributions at a given plane [PDF]

, 2013
Methods for generating beams with arbitrary polarization based on the use of liquid crystal displays have recently attracted interest from a wide range of sources.
Carnicer González, Arturo, Juvells Prades, Ignacio, Maluenda Niubó, David, Martínez-Herrero, Rosario   +3 more
core   +1 more source