Results 31 to 40 of about 63,662 (384)

Modulation of internuclear communication in multinuclear Ruthenium(II) polypyridyl complexes [PDF]

, 2003
The syntheses and characterisation of a series of mononuclear and dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 1,4-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 2,5-bis-[
Adrian Guckian, de Wolf, Frances Weldon, Johannes G. Vos, Wesley R. Browne   +4 more
core   +2 more sources

Functional organization of box C/D RNA-guided RNA methyltransferase [PDF]

, 2020
Box C/D RNA protein complexes (RNPs) catalyze site-specific 2'-O-methylation of RNA with specificity determined by guide RNAs. In eukaryotic C/D RNP, the paralogous Nop58 and Nop56 proteins specifically associate with terminal C/D and internal C'/D ...
Huang, Lin, Lilley, David M. J., Wang, Jiayin, Yang, Zuxiao, Ye, Keqiong   +4 more
core   +2 more sources

METTL3-mediated m6A modification of lnc KCNQ1OT1 promotes doxorubicin resistance in breast cancer by regulating miR-103a-3p/MDR1 axis

Epigenetics, 2023
Doxorubicin (DOX) resistance in breast cancer (BC) poses a huge challenge for the therapeutic effect on BC. Lnc KCNQ1OT1 play crucial roles in chemotherapy resistance.
Zhiyang Zhou, Yukun Cao, Yuan Yang, Shouman Wang, Feiyu Chen   +4 more
doaj   +1 more source

METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung injury

Clinical and Translational Medicine, 2023
Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs), exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also contribute to the pathogenesis and exacerbation of sepsis.
Hao Zhang, Dan Wu, Yanghanzhao Wang, K. Guo, Charles B. Spencer, Lilibeth Ortoga, Mengdi Qu, Yuxin Shi, Yuwen Shao, Zhiping Wang, J. Cata, Changhong Miao   +11 more
semanticscholar   +1 more source

The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression

Heliyon, 2023
Cholangiocarcinoma (CCA) is a serious malignancy originating from the bile ducts and the second most common primary liver cancer. Long non-coding RNA (lncRNA) is a functional lncRNA that plays an important role in human cancers. However, the role and underlying mechanisms of CTBP1-AS2 in CCA remain unknown.In this study, we investigated the functional ...
Zhe Jin, Yahui Liu
openaire   +3 more sources

RNA modification m6Am: the role in cardiac biology

Epigenetics, 2023
Epitranscriptomic modifications have recently emerged into the spotlight of researchers due to their vast regulatory effects on gene expression and thereby cellular physiology and pathophysiology.
Daniel Benak, Frantisek Kolar, Lu Zhang, Yvan Devaux, Marketa Hlavackova   +4 more
doaj   +1 more source

Development and Validation of a Prognostic Index Based on Genes Participating in Autophagy in Patients With Lung Adenocarcinoma

Frontiers in Oncology, 2022
BackgroundLung adenocarcinoma (LUAD) is a deadly respiratory system malignancy with poor prognosis. Autophagy is essential for the beginning, development, and therapy resistance of cancer.
Zi-Xuan Wu, Xuyan Huang, Min-Jie Cai, Pei-Dong Huang, Zunhui Guan   +4 more
doaj   +1 more source

Form-factors and current correlators: chiral couplings L_10(mu) and C_87(mu) at NLO in 1/N(C) [PDF]

, 2008
Using the resonance chiral theory Lagrangian, we perform a calculation of the vector and axial-vector two-point functions at the next-to-leading order (NLO) in the 1/N(C) expansion.
Pich, A., Rosell, I., Sanz-Cillero, J. J.   +2 more
core   +3 more sources

The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer

Journal of experimental & clinical cancer research : CR, 2023
Background Posttranscriptional modification of tumor-associated factors plays a pivotal role in breast cancer progression. However, the underlying mechanism remains unknown. M6A modifications in cancer cells are dynamic and reversible and have been found
Youqin Xu, Mu Song, Ziyang Hong, Wancheng Chen, Qian-bing Zhang, Jianlong Zhou, Chao Yang, Zilong He, Juanjuan Yu, Xiaolin Peng, Qiuhong Zhu, Shaotian Li, Kai-yuan Ji, Min-feng Liu, Qiang Zuo   +14 more
semanticscholar   +1 more source

BOLD signal variability and complexity in children and adolescents with and without autism spectrum disorder

Developmental Cognitive Neuroscience, 2019
Variability of neural signaling is an important index of healthy brain functioning, as is signal complexity, which relates to information processing capacity. Alterations in variability and complexity may underlie certain brain dysfunctions.
Amanda K. Easson, Anthony R. McIntosh
doaj   +1 more source