Results 41 to 50 of about 63,662 (384)
N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases
Journal of Innate Immunity, 2023 The post-transcriptional N6-methyladenosine (m6A) modification of RNA influences stability, transport, and translation with implications for various physiological and pathological processes.
Yan Teng, Jin Yi, Junnian Chen, Lu Yang
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Cyclin D1 integrates G9a-mediated histone methylation. [PDF]
, 2019 Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, and pluripotency.
Casimiro, Mathew C. +13 more
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m6a RNA methylation: the implications for health and disease [PDF]
, 2014 The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
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Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing
Nature Communications, 2023 Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
Zhengjie Zhong +11 more
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Epigenetics, 2023 Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury. No study has used epitranscriptomics to explore the characteristics and mechanism of injury.
Chi Zhang +12 more
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Parkinson's Disease, 2013 Background. Parkinson’s disease (PD) is a neurodegenerative condition with complex subtleties, making it challenging for physicians to fully inform their patients.
Galit Kleiner-Fisman +2 more
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m6A-regulated tumor glycolysis: new advances in epigenetics and metabolism
Molecular Cancer, 2023 Glycolytic reprogramming is one of the most important features of cancer and plays an integral role in the progression of cancer. In cancer cells, changes in glucose metabolism meet the needs of self-proliferation, angiogenesis and lymphangiogenesis ...
Shiwei Yue +6 more
semanticscholar +1 more source
Nature Chemical Biology, 2020 The biological function and origin of m6A in DNA have been widely debated. A new study demonstrates that the majority of m6A in DNA originates from RNA catabolism via a nucleotide salvage pathway.
Spingardi, P, Kriaucionis, S
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m6A RNA Methylation in Cardiovascular Diseases [PDF]
Molecular Therapy, 2020 Cardiovascular diseases (CVDs) remain the leading cause of death and disability worldwide, despite marked improvements in prevention, diagnosis, and early intervention. There is an urgent need to discover more effective therapeutic strategies, which would be facilitated by a more in-depth understanding of CVDs and their underlying molecular mechanisms.
Siyi, Wu +3 more
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Improved $\alpha^4$ Term of the Electron Anomalous Magnetic Moment [PDF]
, 2005 We report a new value of electron $g-2$, or $a_e$, from 891 Feynman diagrams of order $\alpha^4$. The FORTRAN codes of 373 diagrams containing closed electron loops have been verified by at least two independent formulations.
A. Petermann +16 more
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