Results 51 to 60 of about 63,662 (384)

Photon decay in strong magnetic field in heavy-ion collisions [PDF]

open access: yes, 2011
We calculate the photon pair production rate in strong magnetic field created in off-central heavy-ion collisions. Photon decay leads to depletion of the photon yield by a few percent at RHIC and by as much as 20% at the LHC.
A. I. Nikishov   +3 more
core   +5 more sources

Integration Analysis of m6A Regulators and m6A-Related Genes in Hepatocellular Carcinoma

open access: yesBIO Integration, 2021
Abstract Background: N6-Methyladenosine (m6A) RNA methylation of eukaryotic mRNA is involved in the progression of various tumors. We aimed to investigate m6A-related genes and m6A regulators in hepatocellular carcinoma (HCC) and their association with prognosis in HCC.
Jingdun Xie   +7 more
openaire   +2 more sources

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d [PDF]

open access: yes, 2018
N6-methyladenosine (m6A) is the most abundant mRNA modification in eukaryotes, playing crucial roles in multiple biological processes. m6A is catalyzed by the activity of Mettl3, which depends on additional proteins whose precise functions remain poorly ...
Andrade-Navarro, Miguel A.   +15 more
core   +4 more sources

The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

open access: yesJournal of Inflammation Research, 2023
Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H   +7 more
doaj  

Potential Impact of N6-Methyladenosine RNA Methylation on Vision Function and the Pathological Processes of Ocular Diseases: New Discoveries and Future Perspectives

open access: yesFrontiers in Bioscience-Landmark, 2022
N6-methyladenosine (m6A) methylation/modification plays a critical role in various biological processes through post-transcriptional ribonucleic acid (RNA) modification, which involves RNA processing, nuclear export, translation and decay.
Xiaohua Li   +8 more
doaj   +1 more source

m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer

open access: yesMolecular Cancer, 2020
The epigenetic regulation of immune response has been demonstrated in recent studies. Nonetheless, potential roles of RNA N6-methyladenosine (m6A) modification in tumor microenvironment (TME) cell infiltration remain unknown. We comprehensively evaluated
Bo Zhang   +5 more
semanticscholar   +1 more source

m6A methyltransferase METTL3 promotes the progression of prostate cancer via m6A-modified LEF1.

open access: yesEuropean review for medical and pharmacological sciences, 2020
This study aims to uncover the regulatory effects of METTL3 on promoting the progression of prostate cancer (PCa) through N6-Methyladenosine (m6A) methylation on LEF1 mRNA.The relative levels of METTL3 and LEF1 in 48 paired PCa tissues and adjacent ones were determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR).
Ma, X.-X., Cao, Z.-G., Zhao, S.-L.
openaire   +2 more sources

The how and why of lncRNA function: An innate immune perspective. [PDF]

open access: yes, 2020
Next-generation sequencing has provided a more complete picture of the composition of the human transcriptome indicating that much of the "blueprint" is a vastness of poorly understood non-protein-coding transcripts.
Carpenter, Susan   +2 more
core  

METTL3 inhibits anti-tumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer.

open access: yesGastroenterology, 2022
BACKGROUND & AIMS N6-Methyladenosine (m6A) is the most prevalent RNA modification and recognized as an important epitranscriptomic mechanism in colorectal cancer (CRC).
Huarong Chen   +16 more
semanticscholar   +1 more source

Interactive influences of prior knowledge on episodic memory

open access: yesiScience
Summary: Many species adapt to their environments by accruing relevant knowledge and expertise, which in turn shapes memory formation. Human experts remember items in their field better than novices, but different types of knowledge or exposure influence
Erik A. Wing   +2 more
doaj   +1 more source

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