Results 61 to 70 of about 63,662 (384)
Exploring the Epigenetic Regulatory Role of m6A-Associated SNPs in Type 2 Diabetes Pathogenesis
Pharmacogenomics and Personalized Medicine, 2021 Miao Chen,1,2 Weimin Lin,1 Jianru Yi,1,2 Zhihe Zhao1,2 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Department ...
Chen M, Lin W, Yi J, Zhao Z
doaj
FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development
Science, 2022 N6-methyladenosine (m6A) is the most abundant internal modification on mammalian messenger RNA. It is installed by a writer complex and can be reversed by erasers such as the fat mass and obesity-associated protein FTO.
Jiangbo Wei +33 more
semanticscholar +1 more source
Neuroelectric Correlates of Perceptual Awareness During the Auditory Attentional Blink
Brain SciencesBackground: Perceptual awareness refers to the conscious detection and identification of a sensory event. In electrophysiological studies, it is associated with a modality-specific negative-going event-related potential, which can be observed as early as
Claude Alain +4 more
doaj +1 more source
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation
Nucleic Acids Research, 2020 N 6-Methyladenosine (m6A) is the most abundant RNA modification in mammal mRNAs and increasing evidence suggests the key roles of m6A in human tumorigenesis.
Tao Liu +17 more
semanticscholar +1 more source
Nature Communications, 2022 Microbiota-host interactions play critical roles in colorectal cancer (CRC) progression, however, the underlying mechanisms remain elusive. Here, we uncover that Fusobacterium nucleatum (F.
Shujie Chen +16 more
semanticscholar +1 more source
FTO: linking m6A demethylation to adipogenesis [PDF]
Cell Research, 2014 Polymorphism of the FTO gene encoding an N(6)-methyladenosine (m(6)A) RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood.
Moshe Shay, Ben-Haim +2 more
openaire +2 more sources
Photon propagation in a cold axion condensate [PDF]
, 2013 We discuss some striking properties of photons propagating in a cold axion condensate oscillating coherently in time with a frequency $1/m_a$. Three effects are discussed in this contribution: (a) due to the time dependence of the background, photons ...
Espriu, Domenec, Renau, Albert
core +1 more source
Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification
Molecular Cancer, 2022 Background Gastric cancer (GC) is one of the most pernicious tumors that seriously harm human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but correlation between N6-methyladenosine (m6A) and GC metastasis was less ...
Yiyang Hu +10 more
semanticscholar +1 more source
Blending of Cepheids in M33 [PDF]
, 2012 A precise and accurate determination of the Hubble constant based on Cepheid variables requires proper characterization of many sources of systematic error.
Chavez, Joy M. +2 more
core +3 more sources
The RNA m6A reader YTHDF1 is required for acute myeloid leukemia progression.
Cancer Research, 2023 N6-methyladenosine (m6A), the most abundant modification in mRNAs, has been defined as a crucial modulator in the progression of acute myeloid leukemia (AML). Identification of the key regulators of m6A modifications in AML could provide further insights
Yun-Guang Hong +14 more
semanticscholar +1 more source