Results 81 to 90 of about 937,277 (225)
, 2020 N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Kuiyuan Hou (8550516) +8 more
core +1 more source
Deregulation of m6A-RNA methylation impairs adaptive hypertrophic response and drives maladaptation via mTORC1-S6K1-hyperactivation and autophagy impairment. [PDF]
Cell Commun SignalBackground Pressure overload first leads to compensated hypertrophy and secondary to heart failure. m6A-RNA methylation is a fast process for the adaptation of cell composition.
Annamalai K +17 more
europepmc +2 more sources
The Role of m6A RNA Methylation in Cancer: Implication for Nature Products Anti-Cancer Research
Frontiers in Pharmacology, 2022 N6-methyladenosine (m6A) RNA methylation is identified as the most common, abundant and reversible RNA epigenetic modification in messenger RNA (mRNA) and non-coding RNA, especially within eukaryotic messenger RNAs (mRNAs), which post-transcriptionally ...
Na Song +13 more
semanticscholar +1 more source
, 2020 N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Kuiyuan Hou (8550516) +8 more
core +1 more source
Hydroxychloroquine Modulates m6A RNA Methylation in Prostate Cancer Cells
, 2023 Prostate cancer ranks as the second most prevalent cancer in men globally. One of the evolving subjects of investigation in prostate cancer is the role of N6-methyladenosine (m6A) modifications. Hydroxychloroquine (HCQ), an autophagy inhibitor, was shown
Bal Albayrak, Merve Gülsen +3 more
core +2 more sources
Frontiers in Neuroscience, 2021 Little is known about the particular changes of N6-methyladenosine (m6A) RNA methylation in enterovirus (EV) infection among children with neurologic symptoms.
Danping Zhu +6 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2020 Because most studies have focused on the intrinsic carcinogenic pathways of tumors, the underlying role of N6-methyladenosine (m6A) methylation in tumor immune microenvironment (TIME) remains elusive.
Lilan Yi +4 more
semanticscholar +1 more source
The Potential Role of m6A RNA Methylation in the Aging Process and Aging-Associated Diseases
Frontiers in Genetics, 2022 N6-methyladenosine (m6A) is the most common and conserved internal eukaryotic mRNA modification. m6A modification is a dynamic and reversible post-transcriptional regulatory modification, initiated by methylase and removed by RNA demethylase. m6A-binding
Jin Sun +10 more
semanticscholar +1 more source
, 2020 N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Kuiyuan Hou (8550516) +8 more
core +1 more source
, 2021 N6-methyladenosine (m6A) modification on RNA plays an important role in tumorigenesis and metastasis, which could change gene expression and even function at multiple levels such as RNA splicing, stability, translocation, and translation.
Dandan Qi, Baoli Zhu, Xin Ye, Yong Li
core +1 more source