Results 71 to 80 of about 937,277 (225)

Comprehensive Analysis of PD-L1 Expression, Immune Infiltrates, and m6A RNA Methylation Regulators in Esophageal Squamous Cell Carcinoma

Frontiers in Immunology, 2021
Background Esophageal squamous cell carcinoma (ESCC) is one of the most common cancer types and represents a threat to global public health. N6-Methyladenosine (m6A) methylation plays a key role in the occurrence and development of many tumors, but there
Wei Guo, F. Tan, Qilin Huai, Zhen Wang, Fei Shao, Guo-Chao Zhang, Zhen-Lin Yang, Ren-Da Li, Q. Xue, Shu-Geng Gao, Jie He   +10 more
semanticscholar   +1 more source

Table_3_Malignant Evaluation and Clinical Prognostic Values of m6A RNA Methylation Regulators in Glioblastoma.XLSX

, 2020
N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Kuiyuan Hou (8550516), Yixu Ba (8550522), Rui Xie (826938), Shuai Ma (414625), Shaoshan Hu (795277), Jianyang Du (257357), Lei Chen (54296), Shan Mi (8550519), Hang Ji (2432434)   +8 more
core   +1 more source

piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner

Journal of Translational Medicine, 2022
Background Cervical cancer (CC) is one of the most common gynecological tumors that threatens women's health and lives. Aberrant expression of PIWI-interacting RNA (piRNA) is closely related with a range of cancers and can serve as a tumor promoter or ...
Q. Xie, Zhen Li, Xiao Luo, Dan Wang, Yao Zhou, Jing-Ge Zhao, Su-qin Gao, Yongguang Yang, Wanying Fu, Ling-Fei Kong, Tingyi Sun   +10 more
semanticscholar   +1 more source

Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study

, 2021
N6-methyladenosine (m6A) is an abundant epitranscriptomic mark that regulates gene expression to execute cellular developmental programmes and environmental adaptation.
Chuturgoon, Anil A., Terisha Ghazi, Anil A. Chuturgoon, Nagiah, Savania, Savania Nagiah, Ghazi, Terisha   +5 more
core   +1 more source

Effect of m6A RNA Methylation Regulators on Malignant Progression and Prognosis in Renal Clear Cell Carcinoma

Frontiers in Oncology, 2020
Objectives: This study aims to explore the roles of 13 m6A RNA methylation regulators in clear cell renal cell carcinoma (ccRCC), and identify a risk signature and prognostic values of m6A RNA methylation regulators in ccRCC.Materials and Methods: RNA ...
Jiawu Wang, Chengyao Zhang, Chengyao Zhang, Weiyang He, Xin Gou   +4 more
doaj   +1 more source

Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

Nature Communications, 2018
N6-methyladenosine (m6A) is the most abundant epigenetic modification in eukaryotic mRNAs and is essential for multiple RNA processing events during mammalian development and disease control.
Yunshu Wu, Liang Xie, Meng-Yuan Wang, Q. Xiong, Yuchen Guo, Yu Liang, Jing Li, R. Sheng, Peng Deng, Yuan Wang, Rixin Zheng, Yi-Zhou Jiang, L. Ye, Qian-Ming Chen, Xue-Dong Zhou, Shui-Bin Lin, Q. Yuan   +16 more
semanticscholar   +1 more source

LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation

Molecular Medicine, 2022
Background Pyroptosis is a form of programmed cell death involved in the pathophysiological progression of hypoxic pulmonary hypertension (HPH). Emerging evidence suggests that N6-methyladenosine (m6A)-modified transcripts of long noncoding RNAs (lncRNAs)
Xiaoying Wang, Qian Li, Si-Yu He, J. Bai, Cui Ma, Li-Xin Zhang, Xiao-Yu Guan, Hao Yuan, Yi-Ying Li, Xiang-Rui Zhu, Jian Mei, Feng Gao, Da-Ling Zhu   +12 more
semanticscholar   +1 more source

Table_1_Malignant Evaluation and Clinical Prognostic Values of m6A RNA Methylation Regulators in Glioblastoma.DOCX

, 2020
N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Kuiyuan Hou (8550516), Yixu Ba (8550522), Rui Xie (826938), Shuai Ma (414625), Shaoshan Hu (795277), Jianyang Du (257357), Lei Chen (54296), Shan Mi (8550519), Hang Ji (2432434)   +8 more
core   +1 more source

The role of mRNA m6A methylation in the nervous system

Cell & Bioscience, 2019
Epitranscriptomics, also known as “RNA epigenetics”, is a chemical modification for RNA regulation. Ribonucleic acid (RNA) methylation is considered to be a major discovery following the deoxyribonucleic acid (DNA) and histone methylation. Messenger RNA (
Jiashuo Li, Xinxin Yang, Zhipeng Qi, Yanqi Sang, Yanan Liu, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng   +8 more
doaj   +1 more source

The prognostic values of m6A RNA methylation regulators in Uveal melanoma [PDF]

BMC Cancer, 2019
Abstract Purpose: The aim of this study was to identify gene signatures and prognostic values of m6A methylation regulators in uveal melanoma (UM). Methods: The RNA sequencing dataset and corresponding clinical information were downloaded from TCGA and GEO database.
Jing Tang, Qi Wan, Jianqun Lu
openaire   +3 more sources