Results 101 to 110 of about 10,490 (182)
PLoS ONE, 2011 Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner.
Mikhail Lomonosov +5 more
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Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3 [PDF]
, 2013 Hematopoiesis is a classic system with which to study developmental potentials and to investigate gene regulatory networks that control choices among alternate lineages. T-cell progenitors seeding the thymus retain several lineage potentials.
Del Real, Marissa Morales +1 more
core +1 more source
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation
The EMBO JournalPARP-catalysed ADP-ribosylation (ADPr) is important in regulating various cellular pathways. Until recently, PARP-dependent mono-ADP-ribosylation has been poorly understood due to the lack of sensitive detection methods.
Pulak Kar +18 more
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Frontiers in Plant ScienceRehmannia glutinosa is an economically significant medicinal plant. Yet, the structure and sequence of its mitochondrial genome has not been published, which plays a crucial role in evolutionary analysis and regulating respiratory-related macromolecule ...
Tiexin Zeng +8 more
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3005 Integrin Mac-1 Potentiates Neutrophil Adhesion and NET Release in Antiphospholipid Syndrome
Journal of Clinical and Translational Science, 2019 OBJECTIVES/SPECIFIC AIMS: While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the adhesive potential of leukocytes has received considerably less attention.
Gautam Sule +4 more
doaj +1 more source
Nature Communications, 2017 Nature Communications 8: Article number:15559 (2017); Published 30 May 2017; Updated 4 July 2017 The original version of this Article contained an error in the email address of the corresponding author Daniel I. Simon.
Yunmei Wang +13 more
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Postponement and recuperation of Belgian fertility: how are they related to rising female educational attainment? [PDF]
Fertility trends in Europe after 1970 are routinely referred to in terms of the postponement of fertility. The shortening of the effective reproductive lifespan and its association with post-materialist values have raised questions as to whether ...
David De Wachter, Karel Neels
core
The Opioid Peptide Dynorphin a Induces Leukocyte Responses via Integrin Mac-1 (αβ, CD11b/CD18)
Molecular Pain, 2015 Background Opioid peptides, including dynorphin A, besides their analgesic action in the nervous system, exert a broad spectrum of effects on cells of the immune system, including leukocyte migration, degranulation and cytokine production. The mechanisms
Nataly P. Podolnikova +2 more
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On the impossibility of inferring cohort fertility measures from period fertility measures [PDF]
A particularly important struggle faced by demographic analysts is, how to arrive at statements about family formation processes from a cohort perspective from data that are essentially collected on an annual basis.
Evert van Imhoff
core
Haematologica, 2017 Targeting leukemia initiating cells is considered to be an effective way to cure leukemia, for which it is critical to identify novel therapeutic targets.
Feifei Zhang +16 more
doaj +1 more source