Results 31 to 40 of about 10,490 (182)

On Achievable Rate Region of Multiple Coordinated Multiple Access Channels [PDF]

open access: yes, 2011
Coordination between two or more multiple access channel (MAC) receivers can enlarge the achievable rate region of the whole system. This paper focuses on coordination by sharing the codebooks of the users between the receivers of MACs.
Heliot, Fabién   +2 more
core   +1 more source

Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

open access: yesIUCrJ, 2020
Among 15 nonstructural proteins (Nsps), the newly emerging Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) encodes a large, multidomain Nsp3. One of its units is the ADP-ribose phosphatase domain (ADRP; also known as the macrodomain, MacroD),
Karolina Michalska   +6 more
doaj   +1 more source

Detonation interaction with an interface [PDF]

open access: yes, 2007
Detonation interaction with an interface was investigated, where the interface separated a combustible from an oxidizing or inert mixture. The ethylene-oxygen combustible mixture had a fuel-rich composition to promote secondary combustion with the ...
Lieberman, D. H., Shepherd, J. E.
core   +1 more source

Independent Metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae

open access: yesEukaryotic Cell, 2005
ABSTRACT Ace1 and Mac1 undergo reciprocal copper metalloregulation in yeast cells. Mac1 is functional as a transcriptional activator in copper-deficient cells, whereas Ace1 is a transcriptional activator in copper-replete cells. Cells undergoing a transition from copper-deficient to copper-sufficient conditions through a switch in the growth ...
Greg, Keller   +2 more
openaire   +2 more sources

Monocyte-Derived Macrophages-Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis. [PDF]

open access: yesArthritis Rheumatol
Objective Osteoarthritis (OA) is a debilitating joint disease that is characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Laouteouet D   +18 more
europepmc   +2 more sources

Absent regulation of iron acquisition by the copper regulator Mac1 in A. fumigatus

open access: yesBiochemical Journal, 2020
Aspergillus fumigatus is the most common cause of invasive aspergillosis, a life-threatening infection mainly affecting immunocompromised patients. The essential metals copper and iron play crucial roles in virulence of this mold. Recently, the copper-regulatory transcription factor Mac1 was reported to additionally be involved in the control of iron ...
Annie Yap   +2 more
openaire   +2 more sources

Molecular Characteristics of the Conserved Aspergillus nidulans Transcription Factor Mac1 and Its Functions in Response to Copper Starvation

open access: yesmSphere, 2019
Copper (Cu) is an essential trace element in all organisms, and Cu acquisition during periods of starvation is important for cell survival and proliferation.
Zhendong Cai   +4 more
doaj   +1 more source

Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells [PDF]

open access: yesACS Chemical Biology, 2016
The genetic integrity of each organism is intimately tied to the correct segregation of its genome during mitosis. Insights into the underlying mechanisms are fundamental for both basic research and the development of novel strategies to treat mitosis-relevant diseases such as cancer.
Naowras, Al-Obaidi   +3 more
openaire   +2 more sources

Sub-lethal concentrations of chlorhexidine inhibit Candida albicans growth by disrupting ROS and metal ion homeostasis

open access: yesJournal of Oral Microbiology, 2023
Candida albicans is a normal resident of the human oral cavity. It is also the most common fungal pathogen, causing various oral diseases, particularly in immunocompromised individuals.
Qian Jiang   +4 more
doaj   +1 more source

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors [PDF]

open access: yes, 2014
Chronic myeloid leukemia (CML) is initiated and maintained by the tyrosine kinase BCR-ABL which activates a number of signal transduction pathways, including PI3K/AKT signaling and consequently inactivates FOXO transcription factors.
Bhatia   +38 more
core   +2 more sources

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