Results 31 to 40 of about 5,783 (150)

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

Journal of Structural Biology: X, 2022
Dynamic nuclear polarization NMR spectroscopy was used to investigate the effect of the antimicrobial peptide (AMP) maculatin 1.1 on E. coli cells. The enhanced 15N NMR signals from nucleic acids, proteins and lipids identified a number of unanticipated ...
Frances Separovic, Vinzenz Hofferek, Anthony P. Duff, Malcom J. McConville, Marc-Antoine Sani   +4 more
doaj   +1 more source

Transfer of MAC1 to NIH3T3 cells.

, 2016
(a) MAC1 was introduced into NIH3T3 cells using PEG-MMCT (PEG), Eco-MMCT (Eco), or Am-MMCT (Am). MAC1-transferred NIH3T3 cells were selected with G418, and colonies were stained with crystal violet. Representative images of the plates are shown.
Takahiko Hara (365321), Teruhiko Suzuki (238004), Yasuhiro Kazuki (202667), Mitsuo Oshimura (8238)   +3 more
core   +1 more source

Alignment of Mac1 sequences from several betacoronaviruses.

, 2023
The Mac1 sequences of SARS-CoV-2, SARS-CoV, MERS-CoV, and MHV-A59 were obtained from uniport (P0DTC1, P0C6U8, K9N638, and P0C6V0, respectively) and aligned with Geneious Prime version 2022.2.1 using the Clustal Omega setting. Residues shaded in black are
Rahul K. Suryawanshi (2856155), Manasi P. Jogalekar (15096750), Mauricio Montano (7848814), Morgan E. Diolaiti (6054164), Melanie Ott (26926), Irene P. Chen (13775594), James S. Fraser (14710417), Taha Y. Taha (4318396), Alan Ashworth (1270), Gabriella R. Kimmerly (16914269), Chia-Lin Tsou (238845), Nevan J. Krogan (90155), Galen J. Correy (2391727), Maria McCavitt-Malvido (16914263), Luis Martinez-Sobrido (2822348), Ronnie Gascon (16914272), Patrick C. O’Leary (16914266)   +16 more
core   +1 more source

Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicans

Frontiers in Microbiology, 2020
Copper homeostasis is an important determinant for virulence of many human pathogenic fungi such as the highly prevalent yeast Candida albicans. However, beyond the copper transporter Ctr1, little is known regarding other genes and biological processes ...
Inès Khemiri, Faiza Tebbji, Adnane Sellam, Adnane Sellam   +3 more
doaj   +1 more source

Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. [PDF]

PLoS Genetics, 2006
Cryptococcus neoformans is a fungal human pathogen with a bipolar mating system. It undergoes a dimorphic transition from a unicellular yeast to hyphal filamentous growth during mating and monokaryotic fruiting. The traditional sexual cycle that leads to
Xiaorong Lin, Johnny C Huang, Thomas G Mitchell, Joseph Heitman   +3 more
doaj   +1 more source

Transfer of MAC1 to HT1080 cells.

, 2016
(a) MAC1 was introduced into HT1080 cells using PEG-MMCT (PEG) or Am-MMCT (Am). MAC1-transferred G418-resistant HT1080 clones were stained with crystal violet. Representative images of the plates are shown.
Takahiko Hara (365321), Teruhiko Suzuki (238004), Yasuhiro Kazuki (202667), Mitsuo Oshimura (8238)   +3 more
core   +1 more source

Mac1, a fission yeast transmembrane protein localizing to the poles and septum, is required for correct cell separation at high temperatures.

, 2002
International audienceSchizosaccharomyces pombe represents a genetic model system for studying cell polarity and division in eukaryotes. We report here the identification of Mac1, a novel fission yeast protein that localized predominantly to the cell ...
Charbonneau, Michel, Grandin, Nathalie
core   +5 more sources

Nitric oxide increases biofilm formation in Saccharomyces cerevisiae by activating the transcriptional factor Mac1p and thereby regulating the transmembrane protein Ctr1

Biotechnology for Biofuels, 2019
Background Biofilms with immobilized cells encased in extracellular polymeric substance are beneficial for industrial fermentation. Their formation is regulated by various factors, including nitric oxide (NO), which is recognized as a quorum-sensing and ...
Leyun Yang, Cheng Zheng, Yong Chen, Xinchi Shi, Zhuojun Ying, Hanjie Ying   +5 more
doaj   +1 more source

Characterization of Coronaviruses Mac1 Mutant Proteins

, 2023
The coronaviruses macrodomain, also called Mac1, in the nonstructural protein 3 (nsp3) has two important functions: it binds to a protein in the acidic residues (glutamate and aspartate), and hydrolyzes as a mono-ADP-ribose (MAR) from a protein including
Khattabi, Reem Saleh M
core  

The C. neoformans Mac1 Protein Is Polymorphic

, 2013
Translated amino acid sequences for Mac1 from strains B3501α and JEC21α (congenic to B3502a) are depicted. CNG02270 contains a copper-fist DNA binding domain at the N-terminus that is conserved between copper-regulating transcription factors, such as ...
Joseph Heitman (22335), Johnny C Huang (22333), Thomas G Mitchell (22334), Xiaorong Lin (22332)   +3 more
core   +1 more source