Results 51 to 60 of about 5,596 (181)

Nitric oxide increases biofilm formation in Saccharomyces cerevisiae by activating the transcriptional factor Mac1p and thereby regulating the transmembrane protein Ctr1

open access: yesBiotechnology for Biofuels, 2019
Background Biofilms with immobilized cells encased in extracellular polymeric substance are beneficial for industrial fermentation. Their formation is regulated by various factors, including nitric oxide (NO), which is recognized as a quorum-sensing and ...
Leyun Yang   +5 more
doaj   +1 more source

Functional Independence of the Two Cysteine-rich Activation Domains in the Yeast Mac1 Transcription Factor [PDF]

open access: yesJournal of Biological Chemistry, 2000
Mac1 is a transcriptional activator whose activity is inhibited by copper ions. Mutagenesis studies were carried out to map residues important in the copper inhibition of Mac1 activity. Seven new missense mutations were identified that resulted in copper-independent Mac1 transcriptional activation.
G, Keller   +3 more
openaire   +2 more sources

Transfer of MAC1 to NIH3T3 cells.

open access: yes, 2016
(a) MAC1 was introduced into NIH3T3 cells using PEG-MMCT (PEG), Eco-MMCT (Eco), or Am-MMCT (Am). MAC1-transferred NIH3T3 cells were selected with G418, and colonies were stained with crystal violet. Representative images of the plates are shown.
Takahiko Hara (365321)   +3 more
core   +1 more source

Engineering Ustilago maydis for production of tailor-made mannosylerythritol lipids

open access: yesMetabolic Engineering Communications, 2021
Mannosylerythritol lipids (MELs) are surface active glycolipids secreted by various fungi. MELs can be used as biosurfactants and are a biodegradable resource for the production of detergents or pharmaceuticals.
Fabienne Becker   +5 more
doaj   +1 more source

The C. neoformans Mac1 Protein Is Polymorphic

open access: yes, 2013
Translated amino acid sequences for Mac1 from strains B3501α and JEC21α (congenic to B3502a) are depicted. CNG02270 contains a copper-fist DNA binding domain at the N-terminus that is conserved between copper-regulating transcription factors, such as ...
Joseph Heitman (22335)   +3 more
core   +1 more source

Growth dynamics and cyclin expression in cutaneous T-cell lymphoma cell lines

open access: yesDermatology Reports, 2010
We have investigated cell growth dynamics and cyclins B1 and E expression in cell lines derived from mycosis fungoides (MyLa), Sézary syndrome (SeAx), and CD30+ lympho-proliferative diseases (Mac1, Mac2a, JK).
Edyta Biskup   +3 more
doaj   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

open access: yesAdvanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu   +8 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Mac1 Is a QTG Regulating Growth, Melanization, and Filamentation of C. neoformans

open access: yes, 2013
Wild-type strain XL304α and its mac1 mutant were cultured on YPD medium with the indicated concentrations of BCS or copper sulfate at 22 °C (A) and 39 °C (B).
Joseph Heitman (22335)   +3 more
core   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy