Results 41 to 50 of about 5,202 (155)
mBio, 2022 Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
doaj +1 more source
Interactomics of SARS-CoV-2 Macrodomain 1 Reveals Putative Clients of ADP-Ribosyl Hydrolase Activity
VirusesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has greatly impacted public health due to high rates of transmissibility and mutation during the COVID-19 pandemic.
Crissey D. Cameron +3 more
doaj +1 more source
In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide
Journal of Structural Biology: X, 2022 Dynamic nuclear polarization NMR spectroscopy was used to investigate the effect of the antimicrobial peptide (AMP) maculatin 1.1 on E. coli cells. The enhanced 15N NMR signals from nucleic acids, proteins and lipids identified a number of unanticipated ...
Frances Separovic +4 more
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Functional Independence of the Two Cysteine-rich Activation Domains in the Yeast Mac1 Transcription Factor [PDF]
Journal of Biological Chemistry, 2000 Mac1 is a transcriptional activator whose activity is inhibited by copper ions. Mutagenesis studies were carried out to map residues important in the copper inhibition of Mac1 activity. Seven new missense mutations were identified that resulted in copper-independent Mac1 transcriptional activation.
G, Keller +3 more
openaire +2 more sources
Frontiers in Microbiology, 2020 Copper homeostasis is an important determinant for virulence of many human pathogenic fungi such as the highly prevalent yeast Candida albicans. However, beyond the copper transporter Ctr1, little is known regarding other genes and biological processes ...
Inès Khemiri +3 more
doaj +1 more source
Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. [PDF]
PLoS Genetics, 2006 Cryptococcus neoformans is a fungal human pathogen with a bipolar mating system. It undergoes a dimorphic transition from a unicellular yeast to hyphal filamentous growth during mating and monokaryotic fruiting. The traditional sexual cycle that leads to
Xiaorong Lin +3 more
doaj +1 more source
Engineering Ustilago maydis for production of tailor-made mannosylerythritol lipids
Metabolic Engineering Communications, 2021 Mannosylerythritol lipids (MELs) are surface active glycolipids secreted by various fungi. MELs can be used as biosurfactants and are a biodegradable resource for the production of detergents or pharmaceuticals.
Fabienne Becker +5 more
doaj +1 more source
Biotechnology for Biofuels, 2019 Background Biofilms with immobilized cells encased in extracellular polymeric substance are beneficial for industrial fermentation. Their formation is regulated by various factors, including nitric oxide (NO), which is recognized as a quorum-sensing and ...
Leyun Yang +5 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Growth dynamics and cyclin expression in cutaneous T-cell lymphoma cell lines
Dermatology Reports, 2010 We have investigated cell growth dynamics and cyclins B1 and E expression in cell lines derived from mycosis fungoides (MyLa), Sézary syndrome (SeAx), and CD30+ lympho-proliferative diseases (Mac1, Mac2a, JK).
Edyta Biskup +3 more
doaj +1 more source