Results 41 to 50 of about 5,596 (181)
Alignment of Mac1 sequences from several betacoronaviruses.
, 2023 The Mac1 sequences of SARS-CoV-2, SARS-CoV, MERS-CoV, and MHV-A59 were obtained from uniport (P0DTC1, P0C6U8, K9N638, and P0C6V0, respectively) and aligned with Geneious Prime version 2022.2.1 using the Clustal Omega setting. Residues shaded in black are
Rahul K. Suryawanshi (2856155) +16 more
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High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV‑2 Mac1 Macrodomain
, 2022 Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are critical for replication and virus-induced pathogenesis; therefore, these enzymes are a
Yousef M. O. Alhammad (11835133) +16 more
core +3 more sources
mBio, 2022 Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
doaj +1 more source
The Development and creation of a software system for the monitoring system MAC1
International Journal of Mathematics and Physics, 2019 Abstract. A special system of acoustic detectors was created to search for possible correlations between wide air showers and the signal of elastic oscillations from the depths of the earth's crust. They are intended for joint synchronous work with storm installation.
B. A. Iskakov +4 more
openaire +2 more sources
In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide
Journal of Structural Biology: X, 2022 Dynamic nuclear polarization NMR spectroscopy was used to investigate the effect of the antimicrobial peptide (AMP) maculatin 1.1 on E. coli cells. The enhanced 15N NMR signals from nucleic acids, proteins and lipids identified a number of unanticipated ...
Frances Separovic +4 more
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Interactomics of SARS-CoV-2 Macrodomain 1 Reveals Putative Clients of ADP-Ribosyl Hydrolase Activity
VirusesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has greatly impacted public health due to high rates of transmissibility and mutation during the COVID-19 pandemic.
Crissey D. Cameron +3 more
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Results from the MAC1 Vertex Chamber [PDF]
, 1988 In the summer of 1983, the MAC and Mark-II collaborations gave evidence for bottom hadron lifetimes or 1–2 ps2 based on data accumulated at the PEP e + e − storage ring at SLAC. The importance and fundamental nature of this measurement3 prompted the MAC collaboration to propose, in autumn 1983, the addition of a high precision vertex chamber to the MAC
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Frontiers in Microbiology, 2020 Copper homeostasis is an important determinant for virulence of many human pathogenic fungi such as the highly prevalent yeast Candida albicans. However, beyond the copper transporter Ctr1, little is known regarding other genes and biological processes ...
Inès Khemiri +3 more
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Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. [PDF]
PLoS Genetics, 2006 Cryptococcus neoformans is a fungal human pathogen with a bipolar mating system. It undergoes a dimorphic transition from a unicellular yeast to hyphal filamentous growth during mating and monokaryotic fruiting. The traditional sexual cycle that leads to
Xiaorong Lin +3 more
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Transfer of MAC1 to HT1080 cells.
, 2016 (a) MAC1 was introduced into HT1080 cells using PEG-MMCT (PEG) or Am-MMCT (Am). MAC1-transferred G418-resistant HT1080 clones were stained with crystal violet. Representative images of the plates are shown.
Takahiko Hara (365321) +3 more
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