Results 71 to 80 of about 5,596 (181)

The mac1 Mutation Alters the Developmental Fate of the Hypodermal Cells and Their Cellular Progeny in the Maize Anther

Genetics, 1999
Abstract In angiosperm ovules and anthers, the hypodermal cell layer provides the progenitors of meiocytes. We have previously reported that the multiple archesporial cells1 (mac1) mutation identifies a gene that plays an important role in the switch of the hypodermal cells from the vegetative pathway to the meiotic (sporogenous) pathway
W F, Sheridan, E A, Golubeva, L I, Abrhamova, I N, Golubovskaya   +3 more
openaire   +2 more sources

Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration [PDF]

Current Opinion in Pharmacology, 2016
As average life expectancy rises throughout the world, neurodegenerative diseases have emerged as one of the greatest global public heath challenges in modern times. Substantial efforts have been made in researching neurodegenerative diseases over the last few decades, yet their predominantly sporadic nature has made uncovering their etiologies ...
Shih-Heng, Chen, Esteban A, Oyarzabal, Jau-Shyong, Hong   +2 more
openaire   +2 more sources

Beyond CD30: Dual‐Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Single‐cell RNA analyses of paired lesions from CD30+ mycosis fungoides patients demonstrate that brentuximab vedotin (BV) induces immunogenic cell death in both CD30+ and CD30− malignant T cells. BV also targets regulatory T cells and remodels tumor microenvironment, while resistance is driven by impaired IFN responses, drug efflux, and BCL2 ...
Yi Jiang, Pan Lai, Mingjia Li, Yujie Wen, Mengzhou Cao, Yu Xiao, Zhuojing Chen, Jingru Sun, Yang Wang   +8 more
wiley   +1 more source

Monitoring the Hydrological Activities of Antarctic Subglacial Lakes Using CryoSat-2 and ICESat-2 Altimetry Data

Remote Sensing, 2022
Monitoring the hydrological activities of subglacial lakes is critical to understanding the subglacial hydrological system and evaluating the internal mass changes of the Antarctic ice sheet.
Yi Fan, Weifeng Hao, Baojun Zhang, Chao Ma, Shengjun Gao, Xiao Shen, Fei Li   +6 more
doaj   +1 more source

Obesity Disrupts H3K4me3‐Mediated Lactate Accumulation and Efferocytosis in Hypoxic Macrophages

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Obesity disrupts macrophage adaptation to hypoxic microenvironments. In lean conditions, hypoxia induces H3K4me3‐dependent transcriptional programs that promote lactate accumulation, histone lactylation, and efficient efferocytosis. Diet‐induced obesity impairs this epigenetic–metabolic response, resulting in reduced lactate accumulation, defective ...
Kentaro Takahashi, Julia Drolet, Jinghua Liu, Jasmine R. Jackson, Madison Babcock, Muthusamy Thiruppathi, Milie Fang, Tyler Paul, Gayathri Ganesh, Yuri Fukasawa, Yoshikiyo Akasaka, Giamila Fantuzzi, Elizaveta V. Benevolenskaya, Timothy J. Koh, Norifumi Urao   +14 more
wiley   +1 more source

Zn(II) and Cd(II) Complexes of AMT1/MAC1 Homologous Cys/His-Rich Domains: So Similar yet So Different [PDF]

, 2022
Infections caused by Candida species are becoming seriously dangerous and difficult to cure due to their sophisticated mechanisms of resistance. The host organism defends itself from the invader, e.g., by increasing the concentration of metal ions ...
Potok, Paulina, Mos, Magdalena, Paulina Potok (12868145), Rola, Anna, Sławomir Potocki (12868148), Magdalena Mos (430364), Potocki, Sławomir, Anna Rola (12868142), Gumienna-Kontecka, Elżbieta, Elżbieta Gumienna-Kontecka (2431552)   +9 more
core   +1 more source

Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study examined the translation activity across ten stages of maize anther development, integrating transcriptome and small‐peptide data. It linked mutations in translated 3' ORFs to anther sterility, exemplified by Zm00001eb417050_3' ORF (known as APV1). In addition, the data indicated that maize anthers could assimilate CO2 through the stomata in
Chunyu Wang, Yuechao Wu, Shunxi Wang, Han Liu, Siqi Jiang, Yingjia Han, Liuji Wu, Tao Zhang, Mei Zhang   +8 more
wiley   +1 more source

An investigation of the coexistence of 802.11g WLAN and high data rate Bluetooth enabled consumer electronic devices in indoor home and office environments [PDF]

, 2003
The anticipated proliferation of various wireless local area network (WLAN) enabled devices in the near future is likely to result in increased mutual interference in the 2.45 GHz Industrial, Scientific and Medical (ISM) band.
Nix, AR, Fletcher, PN, Arumugam, AK, Doufexi, A   +3 more
core   +1 more source

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

Nature Communications, 2018
Integrin-based therapeutics could block inflammatory processes but they also impair host defence, limiting their usefulness. Here the authors report an anti-Mac1 antibody that blocks its interaction with pro-inflammatory ligand CD40L but not other ...
Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, Ansgar Wiedemann, Konrad Buscher, Jan David Hohmann, Bock Lim, Marina Bäuml, Alex Marki, Maximilian Mauler, Daniel Duerschmied, Zhichao Fan, Holger Winkels, Daniel Sidler, Philipp Diehl, Dirk M Zajonc, Ingo Hilgendorf, Peter Stachon, Timoteo Marchini, Florian Willecke, Maximilian Schell, Björn Sommer, Constantin von zur Muhlen, Jochen Reinöhl, Teresa Gerhardt, Edward F. Plow, Valentin Yakubenko, Peter Libby, Christoph Bode, Klaus Ley, Karlheinz Peter, Andreas Zirlik   +31 more
doaj   +1 more source

Immunofluorescence characterization of innervation and nerve-immune cell interactions in mouse lymph nodes

European Journal of Histochemistry, 2019
The peripheral nervous system communicates specifically with the immune system via local interactions. These interactions include the “hardwiring” of sympathetic/parasympathetic (efferent) and sensory nerves (afferent) to primary (e.g., thymus and bone ...
Dailun Hu, Philip K. Nicholls, Melissa Claus, Yongkang Wu, Zhongli Shi, Wayne K. Greene, Bin Ma   +6 more
doaj   +1 more source