Results 101 to 110 of about 21,344 (285)

Synthesis of bis(indolylmaleimide) macrocycles [PDF]

, 2000
The synthesis of a novel class of macrocyclic bis(indolylmaleimides) is reported. The key step involves the intermolecular connection of 2,2'-bridged indoles with 3,4-dibromo-2,5-dihydro-1H-2,5-pyrroledione (dibromomaleimide) derivatives.
Pongratz, Herwig, Mahboobi, Siavosh, Reindl, Hans, Popp, Alfred, Schollmeyer, Dieter, Dechant, Irene   +5 more
core   +1 more source

“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles

Journal of Nucleic Acids, 2010
A collection of 26 polyammonium cyclophane-type macrocycles with a large structural diversity has been screened for G-quadruplex recognition. A two-step selection procedure based on the FRET-melting assay was carried out enabling identification of ...
Anton Granzhan, David Monchaud, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou   +5 more
doaj   +1 more source

Diaquabromidocopper(II)–18-crown-6–water (1/1/2)

Acta Crystallographica Section E, 2010
In the title compound, [CuBr2(H2O)2]·C12H24O6·2H2O, the CuII atom, which is situated on an inversion centre and has a slightly distorted square-planar geometry, and the two coordinated water molecules are linked to the 18-crown-6 ...
Bo Wang
doaj   +1 more source

Synthesis of Tetrathia–Oligothiophene Macrocycles [PDF]

, 2019
The synthesis of six tetrathia–oligothiophene macrocycles is described with modest ring-closing yields between 21 and 55%. Single-crystal X-ray studies of four of the macrocycles indicated that encapsulated solvent or guest molecules were possible.
Shauna Schechtel (6340484), David J. Press (1742986), Samruddhi Pasalkar (6340481), Todd C. Sutherland (1519747), David J. Press, Chris Gendy, Todd C. Sutherland, Shauna Schechtel, Belinda Heyne (1763851), Samruddhi Pasalkar, Belinda Heyne, Chris Gendy (1899601)   +11 more
core   +1 more source

1,2,3-Triazolium macrocycles in supramolecular chemistry

Beilstein Journal of Organic Chemistry, 2019
In this short review, we describe different pathways for synthesizing 1,2,3-triazolium macrocycles and focus on their application in different areas of supramolecular chemistry.
Mastaneh Safarnejad Shad, Pulikkal Veettil Santhini, Wim Dehaen   +2 more
doaj   +1 more source

Macrocycle-Based Supramolecular Drug Delivery Systems: A Concise Review

Molecules
Efficient delivery of therapeutic agents to the lesion site or specific cells is an important way to achieve “toxicity reduction and efficacy enhancement”. Macrocycles have always provided many novel ideas for drug or gene loading and delivery processes.
Yanrui Yang, Pengcheng Li, Haibo Feng, Rui Zeng, Shanshan Li, Qixiong Zhang   +5 more
doaj   +1 more source

Evaluation of the Interaction between Long Telomeric DNA and Macrocyclic Hexaoxazole (6OTD) Dimer of a G-quadruplex Ligand

Molecules, 2013
Macrocyclic hexaoxazole dimer of L2H2-6OTD-dimer (3) was newly synthesized as a telomeric G-quadruplex (G4) ligand, and interaction with long telomeric DNAs telo48, 72, and 96 was evaluated by means of electrophoresis mobility shift assay, CD spectra ...
Kazuo Nagasawa, Hiroyuki Seimiya, Takahiro Nakamura, Satoki Majima, Keisuke Iida   +4 more
doaj   +1 more source

Olefinic-Lactone Cyclizations to Macrocycles [PDF]

, 2016
Olefinic-lactone cyclization reactions that result in the generation of macrocycles are ...
Jon D. Rainier (1688194), John C. Rohanna (2398009)   +1 more
core   +1 more source

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

Angewandte Chemie International Edition, EarlyView.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang, Clement Schneider, Zarley Rebholz, Stefan Schulz, Kathy Darragh, Jeroen S. Dickschat   +5 more
wiley   +1 more source

Aromatic Oligoamide Macrocycles with a Backbone of Reduced Constraint [PDF]

, 2016
Oligoamide macrocycles with a backbone partially constrained by hydrogen bonds have been prepared. These macrocycles, carrying multiple H-bonding side chains, underwent strong aggregation in solution and form long fibers in the solid state.
Mark Kline (1909393), Xiaoxi Wei (1909390), Bing Gong (1602628)   +2 more
core   +1 more source