Results 161 to 170 of about 20,280 (253)

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

Macrocyclic Peptides Containing an Imidazopyridinium (IP⁺) Unit Display Enhanced Passive Cell Permeability. [PDF]

J Am Chem Soc
Li B, Parker J, Briggs S, Dong J, Wang C, Fu CW, Burke JM, Kodadek T.   +7 more
europepmc   +1 more source

Diagnosis and Off‐Label Treatment of Subcutaneous Putative Dracunculoid Nematodes in Apteronotus albifrons Originating From Wild‐Caught Fisheries

Journal of Fish Diseases, EarlyView.
ABSTRACT Apteronotus albifrons (Gymnotiformes: Apteronotidae), commonly known as the black ghost knifefish, is a high‐value ornamental fish that is susceptible to various parasites. The affected fish were wild‐caught fisheries and subsequently introduced into a commercial breeding system.
Pedro Henrique Magalhães Cardoso, Simone de Carvalho Balian, Herbert Sousa Soares, Marcelo Bahia Labruna, Gracienhe Gomes dos Santos, José Blanchard Girão Ribeiro Filho, Mauricio Laterça Martins   +6 more
wiley   +1 more source

On-Resin Synthesis and Diversification of Macrocyclic Disulfide Bridge Peptidomimetics via Bifunctional 5-Iodo-1,4-Triazoles. [PDF]

J Org Chem
Malone MA, Shepperson OA, Simms JE, Reid AJ, Jamieson AG.   +4 more
europepmc   +1 more source

Syntheses of Macrocyclic Compounds

Journal of Synthetic Organic Chemistry, Japan, 1966
openaire   +2 more sources

Pharmacokinetics of Moxidectin in Bare‐Nosed Wombats (Vombatus ursinus) After Intravenous, Sub‐Cutaneous and Transdermal Administration

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The anti‐parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare‐nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usage, knowledge of species‐specific pharmacokinetics of moxidectin in bare‐nosed wombats is still limited ...
E. K. Stott, L. F. Skerratt, T. Whittem, M. Leeming, K. Pillay, G. S. Doran, B. Gardner, M. Lynch, M. Klein, P. Holz, T. Chen, J. Hufschmid, A. P. Woodward   +12 more
wiley   +1 more source

A Sensitive Electrochemical Sensor Based on Calix[n]arene-Modified PGE for the Determination of Tofacitinib in Human Urine Samples and Pharmaceutical Dosage Forms. [PDF]

ACS Omega
Sardohan Koseoglu T, Yalabik A, Koseoglu H.   +2 more
europepmc   +1 more source

Hydroxyaldehyde and formyl photoproducts of protoporphyrin IX formed under photodynamic diagnosis and therapy irradiation conditions

Photochemistry and Photobiology, EarlyView.
Photoproducts of the photosensitizer protoporphyrin IX (PpIX) may have diagnostic and therapeutic relevance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These photoproducts possess fluorescence and photosensitizing properties and could serve as a complementary dosimetry index alongside photosensitizer photobleaching. The formation of
Sochi J. Ogbonna, Katsuyoshi Masuda, Hisanao Hazama   +2 more
wiley   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Macrocyclic geminal diols: synthesis, structures, stability and photophysical properties. [PDF]

Chem Sci
Zou B, Chen X, Liu H, Wen S, Huang J, Wei H, Huang J, Gu Y, Xu B, Fan J, Jiang HW.   +10 more
europepmc   +1 more source