Results 81 to 90 of about 888,704 (294)

Accurate quantification of water-macromolecule exchange induced frequency shift: Effects of reference substance

, 2013
Water–macromolecule exchange induces a bulk water frequency shift contributing to the contrast in phase imaging. For separating the effects of the water–macromolecule exchange and the macromolecule susceptibility, appropriate internal or external ...
Zhong, K., Speck, O., Smalla, K., Leutritz, T., Hilfert, L.   +4 more
core   +1 more source

Dendritic macromolecule and the preparation thereof [PDF]

, 1997
The invention relates to a dendritic macromolecule comprising a core and branches emanating from the core wherein the branches are based on vinyl cyanide and/or fumaryl dinatrile units.
Man, HCJ de, Reintjens, RWEG Rafael, Brabander-van den Berg, de, E.M.M., Brabander, EMM de, Nijenhuis, AJ, Meijer, E.W., Vandenbooren, F.H.A.M., Vandenbooren, FHAM, Meijer, EW Bert, Stoelwinder, C.J.C., Bosman, HJM Bert, Castelijns, A.M.C.F., Stoelwinder, CJC, Castelijns, AMCF Anna, Bosman, H.J.M., Reintjens, R.W.E.G., Man, de, H.C.J., Nijenhuis, A.J.   +17 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Electronic and Magnetic Properties of a Three-Arm Nonconjugated Open-Shell Macromolecule

, 2021
Nonconjugated radical polymers (i.e., macromolecules with aliphatic backbones that have stable open-shell sites along their pendant groups) have arisen as an intriguing complement to π-conjugated polymers in organic electronic devices and may prove to ...
Hyunki Yeo (5226650), Hamas Tahir (11707034), Bryan W. Boudouris (1301538), Neil R. Dilley (3003648), Siddhartha Akkiraju, Ying Tan, Hyunki Yeo, Neil R. Dilley, Brett M. Savoie, Siddhartha Akkiraju (1544068), Brett M. Savoie (1293810), Ying Tan (346135), Hamas Tahir, Bryan W. Boudouris   +13 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Improved prospective frequency correction for macromolecule-suppressed GABA editing with metabolite cycling at 3T

, 2021
Macromolecule-suppressed GABA-editing with symmetrical suppression is often preferred over conventional GABA-editing due to its greater specificity. However, this pulse sequence is more sensitive to magnetic field instabilities than conventional GABA ...
Hock, A., Chan, K., Edden, R., Henning, A., MacMillan, E.   +4 more
core  

Editorial: Microbial Communities and Metabolisms Involved in the Degradation of Cellular and Extracellular Organic Biopolymers

Frontiers in Microbiology, 2022
S. Emil Ruff
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Variations of macromolecule ratios between premature and term brains around term.

, 2016
A: Macromolecule signals processing with QUEST for spectra obtained with a TE of 30 ms. The fitted spectrum of all macromolecule signals (“Macromolecules”) is the sum of 12 different fitted macromolecules: MM_9 (δppm = 0.9), MM_12 (δppm = 1.2), MM_14 ...
Meriam Koob (2621047), Sylviane Confort-Gouny (30607), Angèle Viola (30605), Hélène Ratiney (3070515), Patrick J. Cozzone (30610), Nadine Girard (3070518), Yann Le Fur (107392), Patrick Viout (3070512)   +7 more
core   +1 more source