Results 11 to 20 of about 420,110 (262)

Activation of Murine Macrophages [PDF]

Current Protocols in Immunology, 2008
AbstractOur understanding of cell mediated immunity (CMI) has revealed the importance of activated macrophages as key immune effector cells. Over the past decade, we have come to realize that macrophages exhibit remarkable plasticity, and different populations of macrophages with distinct physiologies can develop in response to different stimuli.
David M, Mosser, Xia, Zhang
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Macrophage Activation in Systemic Sclerosis [PDF]

JACC: Basic to Translational Science
Maria Caterina Turco, PhD, Nicoletta Del Papa, MD, Marco Vicenzi, MD, Liberato Marzullo, PhD, Alessandra Rosati, PhD, Margot De Marco, PhD   +5 more
doaj   +2 more sources

Tranglutaminase 2 contributes to the asthmatic inflammation by modulating activation of alveolar macrophages

Immunity, Inflammation and Disease, 2021
Background Transglutaminase 2 (TG2), a multifunctional calcium‐dependent acyltransferase, is upregulated in asthmatic airways and reported to play a role in the pathogenesis of allergic asthma.
Hyun Seung Lee, Da‐Eun Park, Boram Bae, Keunhee Oh, Jae Woo Jung, Dong‐Sup Lee, In‐Gyu Kim, Sang‐Heon Cho, Hye‐Ryun Kang   +8 more
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Macrophage Activation Led Acute Heart Failure Managed Successfully with Immunosuppression

Journal of Blood Medicine, 2021
Karan Seegobin,1 Muhamad Alhaj Moustafa,1 Umair Majeed,1 Jordan C Ray,2 Marwan Shaikh,1 Liuyan Jiang,3 Han W Tun1 1Department of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, 32224, USA; 2Departmentof Cardio-Oncology, Mayo Clinic ...
Seegobin K, Alhaj Moustafa M, Majeed U, Ray JC, Shaikh M, Jiang L, Tun HW   +6 more
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XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury

Redox Biology, 2022
Hepatocellular cell death and macrophage proinflammatory activation contribute to the pathology of various liver diseases, during which XBP1 plays an important role.
Zheng Liu, Mingming Wang, Xun Wang, Qingfa Bu, Qi Wang, Wantong Su, Lei Li, Haoming Zhou, Ling Lu   +8 more
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Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles

BMC Bioinformatics, 2019
Background Macrophages show versatile functions in innate immunity, infectious diseases, and progression of cancers and cardiovascular diseases. These versatile functions of macrophages are conducted by different macrophage phenotypes classified as ...
Ricardo Ramirez, Allen Michael Herrera, Joshua Ramirez, Chunjiang Qian, David W. Melton, Paula K. Shireman, Yu-Fang Jin   +6 more
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Macrophage activation unveiled [PDF]

The Journal of Experimental Medicine, 2005
In the early 1960s, George Mackaness showed that macrophages from mice infected with intracellular bacteria could launch an indiscriminate attack against unrelated bacteria. Thus began an explosion of research on the biology of what Mackaness first termed “macrophage activation.”
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Does early treatment of macrophage activation syndrome prevent fatal outcome in patients with severe systemic juvenile idiopathic arthritis?

Rheumatology, 2014
Macrophage activation syndrome (MAS), a rare complication of various diseases, mainly systemic inflammatory connective tissue disorders, is being increasingly recognized.
Marzena Janczewska, Teresa Kołcun-Penkowska   +1 more
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Metabolism fine-tunes macrophage activation

eLife, 2016
A signaling pathway that rewires metabolism in macrophages to trigger changes in gene expression has been identified.
AnnMarie Torres, Liza Makowski, Kathryn E Wellen   +2 more
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Macrophage activation syndrome in COVID-19

Акушерство, гинекология и репродукция, 2021
The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests and ferritin levels reaching hundreds, and sometimes ...
K. N. Grigorieva, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, D. V. Blinov, V. I. Tsibizova, D. A. Ponomarev, A. S. Shkoda, E. A. Orudzhova, E. Grandone, G. Rizzo, A. D. Makatsariya   +11 more
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