Results 21 to 30 of about 420,110 (262)
Metabolic Regulation of Macrophage Activation
Journal of Innate Immunity, 2021 Macrophages, the central mediators of innate immune responses, being in the first-line of defense, they have to readily respond to pathogenic or tissue damage signals to initiate the inflammatory cascade.
Ourania Kolliniati +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 BackgroundNicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs).
Fengqi Duan +8 more
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Scientific Reports, 2021 Hyperactivation of the immune system through obesity and diabetes may enhance infection severity complicated by Acute Respiratory Distress Syndrome (ARDS).
Abu Saleh Md Moin +4 more
doaj +1 more source
Activation of Macrophages by Peroxidases
Experimental Biology and Medicine, 1986 Peritoneal macrophages from C57BL/6 mice were activated in vitro with various peroxidases and their cytotoxic activity toward 3T12 cells was determined. Destruction of 3T12 cells by macrophages stimulated with horseradish peroxidase, lactoperoxidase, and microperoxidase was observed at peroxidase concentrations as low as 9, 1.6, and 200 nM ...
R Q, Wei +3 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundSustained and dysfunctional macrophage activation promotes inflammatory cardiometabolic disorders, but the role of long intergenic noncoding RNA (lincRNA) in human macrophage activation and cardiometabolic disorders is poorly defined.
Hanrui Zhang +14 more
doaj +1 more source
Modulation of macrophage activation by prostaglandins [PDF]
Mediators of Inflammation, 1996 The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor‐α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration‐dependent fashion, the lipopolysaccharide‐induced generation of nitric oxide and tumour necrosis factor‐α.
SAUTEBIN, LIDIA +3 more
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Lipase Activity in Leukocytes and Macrophages [PDF]
Blood, 1964 Abstract A method is described for the quantitative determination of alkaline lipase activity of blood cells. The pH optimum of the enzyme in macrophages and lymphocytes from patients with chronic lymph-leukemia is 9.2, the optimum substrate (triglyceride) concentration is 7 x 10-2 M, and the Michaelis constant approximately 4.3 x 10-2 M.
H, BRAUNSTEINER +3 more
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Ecotoxicology and Environmental SafetyWe have previously shown that excessive activation of macrophage proinflammatory activity plays a key role in TCE-induced immune liver injury, but the mechanism of polarization is unclear. Recent studies have shown that TLR9 activation plays an important
Lei Gao +8 more
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Emerging Infectious Diseases, 2019 Ebola virus disease (EVD) is associated with elevated cytokine levels, and hypercytokinemia is more pronounced in fatal cases. This type of hyperinflammatory state is reminiscent of 2 rheumatologic disorders known as macrophage activation syndrome and ...
Anita K. McElroy +13 more
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Activation of GPER1 in macrophages ameliorates UUO-induced renal fibrosis
Cell Death and Disease, 2023 Numerous studies have proven the critical role of macrophages in the renal fibrosis process. Notably, G Protein-coupled Estrogen Receptor 1 (GPER1), a novel estrogen receptor, has been shown to play a ubiquitous role in regulating macrophage activities ...
Lin Xie +10 more
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