Results 31 to 40 of about 2,007,152 (308)
Lipase Activity in Leukocytes and Macrophages [PDF]
Blood, 1964 Abstract A method is described for the quantitative determination of alkaline lipase activity of blood cells. The pH optimum of the enzyme in macrophages and lymphocytes from patients with chronic lymph-leukemia is 9.2, the optimum substrate (triglyceride) concentration is 7 x 10-2 M, and the Michaelis constant approximately 4.3 x 10-2 M.
H, BRAUNSTEINER +3 more
openaire +3 more sources
Dietary fatty acids modulate inflammatory cytokine production through activation of MAP kinases [PDF]
, 2007 Polyunsaturated fatty acids (PUFA) have therapeutic effects in inflammatory diseases, however the specific mechanisms by which they exert these effects have not yet been defined.
Braddish, Della
core +1 more source
Modulation of macrophage activation by prostaglandins [PDF]
Mediators of Inflammation, 1996 The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor‐α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration‐dependent fashion, the lipopolysaccharide‐induced generation of nitric oxide and tumour necrosis factor‐α.
SAUTEBIN, LIDIA +3 more
openaire +4 more sources
Macrophages as a source of tumoricidal activity (tumor-necrotizing factor) [PDF]
, 1980 Macrophage-enriched peritoneal exudate cells from mice infected with Mycobacterium bovis BCG, macrophage-like tumor cells (PU 5-1.8), and peritoneal macrophages propagated in vitro with macrophage growth factor released tumoricidal activity into the ...
Mannel, D N +5 more
core +1 more source
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]
, 2012 Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Anders, Hans-Joachim, Weidenbusch, Marc
core +1 more source
Ecotoxicology and Environmental SafetyWe have previously shown that excessive activation of macrophage proinflammatory activity plays a key role in TCE-induced immune liver injury, but the mechanism of polarization is unclear. Recent studies have shown that TLR9 activation plays an important
Lei Gao +8 more
doaj +1 more source
Activation of GPER1 in macrophages ameliorates UUO-induced renal fibrosis
Cell Death and Disease, 2023 Numerous studies have proven the critical role of macrophages in the renal fibrosis process. Notably, G Protein-coupled Estrogen Receptor 1 (GPER1), a novel estrogen receptor, has been shown to play a ubiquitous role in regulating macrophage activities ...
Lin Xie +10 more
doaj +1 more source
CSF-1 as a regulator of macrophage activation and immune responses [PDF]
, 2003 Macrophage activation is a key determinant of susceptibility and pathology in a variety of inflammatory diseases. The extent of macrophage activation is tightly regulated by a number of pro-inflammatory cytokines (e.g.
Sweet, MJ +3 more
core
Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Platt, A. +16 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source