Results 21 to 30 of about 1,228,727 (302)
Advances in the role of STAT3 in macrophage polarization
Frontiers in Immunology, 2023 The physiological processes of cell growth, proliferation, differentiation, and apoptosis are closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has an impact on the onset and progression of a number of inflammatory ...
T. Xia +7 more
semanticscholar +1 more source
Regulatory Mechanism of M1/M2 Macrophage Polarization in the Development of Autoimmune Diseases
Mediators of Inflammation, 2023 Macrophages are innate immune cells in the organism and can be found in almost tissues and organs. They are highly plastic and heterogeneous cells and can participate in the immune response, thereby playing a crucial role in maintaining the immune ...
Yuan Peng +7 more
semanticscholar +1 more source
Epigenetic regulation of macrophage polarization in wound healing
Burns & Trauma, 2023 The immune microenvironment plays a critical role in regulating skin wound healing. Macrophages, the main component of infiltrating inflammatory cells, play a pivotal role in shaping the immune microenvironment in the process of skin wound healing ...
Cheng Chen +5 more
semanticscholar +1 more source
Microbiology Spectrum, 2023 Salmonella is one of the most important enteric pathogens worldwide, which is able to cause lethal systemic infection via survival and replication in host macrophages.
Xinyue Wang +7 more
doaj +1 more source
Advances in the study of macrophage polarization in inflammatory immune skin diseases
Journal of Inflammation, 2023 When exposed to various microenvironmental stimuli, macrophages are highly plastic and primarily polarized into the pro-inflammatory M1-type and the anti-inflammatory M2-type, both of which perform almost entirely opposing functions.
Tingting Xia +10 more
semanticscholar +1 more source
Royal Society Open Science, 2022 We proposed a dynamic stochastic mathematical model to evaluate the role of macrophage polarization in plaque development. The dynamic process of macrophages from proliferation to death was simulated under different lipid microenvironments.
Mengchen Liu +4 more
doaj +1 more source
Metabolic Reprograming in Macrophage Polarization [PDF]
Frontiers in Immunology, 2014 Studying the metabolism of immune cells in recent years has emphasized the tight link existing between the metabolic state and the phenotype of these cells. Macrophages in particular are a good example of this phenomenon. Whether the macrophage obtains its energy through glycolysis or through oxidative metabolism can give rise to different phenotypes ...
Silvia Galván-Peña +1 more
openaire +4 more sources
Macrophage Polarity and Disease Control [PDF]
International Journal of Molecular Sciences, 2021 Macrophages are present in most human tissues and have very diverse functions. Activated macrophages are usually divided into two phenotypes, M1 macrophages and M2 macrophages, which are altered by various factors such as microorganisms, tissue microenvironment, and cytokine signals.
Suguru Kadomoto +2 more
openaire +2 more sources
Macrophage Polarization: An Important Candidate Regulator for Lung Diseases
Molecules, 2023 Macrophages are crucial components of the immune system and play a critical role in the initial defense against pathogens. They are highly heterogeneous and plastic and can be polarized into classically activated macrophages (M1) or selectively activated
L. Deng +8 more
semanticscholar +1 more source
Segmentation based tracking of cells in 2D+time microscopy images of macrophages [PDF]
, 2023 The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse microscopy macrophage data.
arxiv +1 more source