Results 31 to 40 of about 1,228,727 (302)

Macrophage Polarization Comes of Age [PDF]

open access: yesImmunity, 2005
Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells ( [this issue of ...
A. Mantovani, A. Sica, M. Locati
openaire   +4 more sources

The role of immunometabolism in macrophage polarization and its impact on acute lung injury/acute respiratory distress syndrome

open access: yesFrontiers in Immunology, 2023
Lung macrophages constitute the first line of defense against airborne particles and microbes and are key to maintaining pulmonary immune homeostasis. There is increasing evidence suggesting that macrophages also participate in the pathogenesis of acute ...
Lian Wang   +5 more
semanticscholar   +1 more source

Effects of mesoporous SiO2-CaO nanospheres on the murine peritoneal macrophages -- Candida albicans interface [PDF]

open access: yesInt Immunopharmacol International Immunopharmacology. 2021 Mar 20;94:107457, 2021
The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a central role in host defense and are responsible for in vivo nanoparticle trafficking.
arxiv   +1 more source

Macrophage Polarization and Osteoporosis: A Review [PDF]

open access: yesNutrients, 2020
Over 200 million people suffer from osteoporosis worldwide. Individuals with osteoporosis have increased rates of bone resorption while simultaneously having impaired osteogenesis. Most current treatments for osteoporosis focus on anti-resorptive methods to prevent further bone loss.
Joseph Muñoz   +3 more
openaire   +3 more sources

Macrophage Polarization in Health and Disease [PDF]

open access: yesThe Scientific World JOURNAL, 2011
Macrophages are terminally differentiated cells of the mononuclear phagocyte system that also encompasses dendritic cells, circulating blood monocytes, and committed myeloid progenitor cells in the bone marrow. Both macrophages and their monocytic precursors can change their functional state in response to microenvironmental cues exhibiting a marked ...
Cassetta L, Cassol E, POLI , GUIDO
openaire   +4 more sources

Macrophage polarization in inflammatory bowel disease

open access: yesCell communication and signaling : CCS, 2023
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research efforts, which have contributed to gradual improvements in our understanding of IBD diagnosis and therapeutic approaches.
Kun Zhang   +3 more
semanticscholar   +1 more source

The different faces of the macrophage in asthma [PDF]

open access: yes, 2020
PURPOSE OF REVIEW: Asthma is a chronic inflammatory disease in which changes in macrophage polarization have been shown to contribute to the pathogenesis.
de Groot, Linsey E S   +2 more
core   +1 more source

Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]

open access: yesBull Math Biol 85, 37 (2023), 2022
Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv   +1 more source

Macrophage Polarization is Deregulated in Haemophilia [PDF]

open access: yesThrombosis and Haemostasis, 2019
AbstractMacrophages make important contributions to inflammation and wound healing. We show here that macrophage polarization is deregulated in haemophilia in response to macrophage colony-stimulating factor (M-CSF) and partially in response to granulocyte-macrophage colony-stimulating factor (GM-CSF).
Knowles, Lynn M.   +5 more
openaire   +2 more sources

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