Results 71 to 80 of about 87,748 (307)

El origen de la universidad Incluyente en México: Su evolución y retos

open access: yesRevista Biológico Agropecuaria Tuxpan, 2020
Desde el desarrollo de los tiempos, la educación ha ido evolucionando, ya que esto ha traído la inclusión de alumnos con diversas variantes en su desarrollo, y con esto podemos ver que en México, ha sido una continua inclusión dentro de las formas de ...
Marisa Aideé Ariaza Santillán   +4 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

Maestros que investigan: un estatus aún en disputa [PDF]

open access: diamond, 2021
Nicolás Aguilar-Forero, Gary Cifuentes
openalex   +1 more source

Concepciones de interculturalidad y práctica en aula: estudio con maestros de comunidades shipibas en el Perú

open access: yesEducación, 2019
Este artículo presenta resultados de una investigación cualitativa y comparativa. Tuvo como objetivo general identificar las concepciones de interculturalidad de los docentes de dos escuelas interculturales bilingües shipibo-castellano en Lima y dos en ...
Nora Cépeda García   +2 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

State of the educational research project: “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?”

open access: yesEducação (Santa Maria. Online), 2012
The paper presents a State of the Art regarding the research project “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?” (EDU2009-13460, Subprograma EDUC).
Laura Domingo   +2 more
doaj   +1 more source

Maternal asthma and early fetal growth, the MAESTRO study [PDF]

open access: hybrid, 2021
Gustaf Rejnö   +4 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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