Results 101 to 110 of about 2,035 (177)

Human Maf1 is phosphorylated and becomes dephosphorylated after rapamycin and MMS treatment.

open access: yes, 2013
A) Nuclear extract from a HEK 293 cell line expressing HA-tagged Maf1 either untreated (upper panel), or treated with rapamycin (middle panel) or MMS (lower panel) was incubated with nothing, CIAP with or without phosphatase inhibitors, or phosphatase ...
Jaime H. Reina (23140)   +2 more
core   +1 more source

Engineering Saccharomyces cerevisiae for the production of the valuable monoterpene ester geranyl acetate

open access: yesMicrobial Cell Factories, 2018
Background Geranyl acetate is widely used in the fragrance and cosmetic industries, and thus has great economic value. However, plants naturally produce a mixture of hundreds of esters, and geranyl acetate is usually only present in trace amounts, which ...
Tao Wu   +4 more
doaj   +1 more source

A Deep Learning Approach to Weed Eradication in Precision Agriculture

open access: yesThe Journal of Engineering, Volume 2025, Issue 1, January/December 2025.
This study develops a deep learning framework for precise weed identification in wheat fields to enable targeted herbicide application. We evaluated six CNN architectures, with SqueezeNet emerging as the most efficient, achieving an optimal balance between high accuracy and low computational complexity.
Sarfaraz Khan Khalil   +4 more
wiley   +1 more source

Fabrication and characterization of solid lipid nano-formulation of astraxanthin against DMBA-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway

open access: yesDrug Delivery, 2019
In the current experimental study, we scrutinized the chemoprotective effect of astraxanthin against the 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway.
Tao Sun   +4 more
doaj   +1 more source

Maf1 is a central coordinator of metabolic signals.

open access: yes, 2014
Shown is a model depicting the proposed mechanism for the regulation of Maf1 expression by PTEN and the consequences of altered Maf1 expression on gene expression pathways that regulate the oncogenic potential of cells.
Louis Dubeau (193226)   +7 more
core   +1 more source

Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation

open access: yes, 2011
Maf1 protein is a global negative regulator of RNA polymerase (Pol) III transcription conserved from yeast to man. We report that phosphorylation of Maf1 by casein kinase II (CK2), a highly evolutionarily conserved eukaryotic kinase, is ...
Janusz Dębski   +5 more
core   +1 more source

Robust repression of tRNA gene transcription during stress requires protein arginine methylation

open access: yesLife Science Alliance, 2019
This work examines how protein arginine methylation of Rpc31, a subunit of RNA Pol III, promotes negative regulation of tRNA biogenesis in the context of cellular stress. Protein arginine methylation is an important means by which protein function can be
Richoo B Davis   +4 more
doaj   +1 more source

Table7_Contrasting effects of whole-body and hepatocyte-specific deletion of the RNA polymerase III repressor Maf1 in the mouse.XLSX

open access: yes, 2023
MAF1 is a nutrient-sensitive, TORC1-regulated repressor of RNA polymerase III (Pol III). MAF1 downregulation leads to increased lipogenesis in Drosophila melanogaster, Caenorhabditis elegans, and mice.
François Mange (16908380)   +7 more
core   +1 more source

Maf1 negatively regulates fatty acid synthase (FASN) and acetyl-coA carboxylase (ACC1) expression.

open access: yes, 2014
(A) Decreased Maf1 expression increases FASN and ACC1 mRNA. A murine hepatocyte cell line was transiently transfected with non-silencing scrambled mismatch (mm) RNA or siRNA targeting Maf1. RNA was isolated and qRT-PCR was performed.
Louis Dubeau (193226)   +7 more
core   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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