Results 81 to 90 of about 2,035 (177)

PTEN regulates Maf1 protein expression.

open access: yes, 2014
(A) Maf1 expression is decreased in mouse cells and tissues lacking PTEN. Protein lysates were isolated from wild-type and Pten−/− MEFs; livers of 1 month old PtenloxP/loxP; Alb-Cre− (+/+; n = 4) and PtenloxP/loxP; Alb-Cre+ (−/−; n = 3) mice; and ...
Louis Dubeau (193226)   +7 more
core   +1 more source

Sub1 and Maf1, two effectors of RNA polymerase III, are involved in the yeast quiescence cycle.

open access: yesPLoS ONE, 2014
Sub1 and Maf1 exert an opposite effect on RNA polymerase III transcription interfering with different steps of the transcription cycle. In this study, we present evidence that Sub1 and Maf1 also exhibit an opposite role on yeast chronological life span ...
Joël Acker   +5 more
doaj   +1 more source

Loc4Lnc: Accurate prediction of long noncoding RNA subcellular localization via enhanced RNA sequence representation

open access: yesQuantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Long noncoding RNAs (lncRNAs) are crucial in gene regulation, chromatin architecture, and cellular differentiation, playing significant roles in various diseases and serving as potential biomarkers and therapeutic targets. Understanding their precise subcellular localization is essential for elucidating their functions in biological pathways ...
Yujia Cheng, Xiaoyong Pan, Yang Yang
wiley   +1 more source

Copy Number Variation Discovery in South African Nguni-Sired and Bonsmara-Sired Crossbred Cattle

open access: yesAnimals, 2023
Crossbreeding forms part of Climate-Smart beef production and is one of the strategies to mitigate the effects of climate change. Two Nguni-sired and three Bonsmara-sired crossbred animals underwent whole genome sequencing.
Bhaveni B. Kooverjee   +4 more
doaj   +1 more source

GRB2 Promotes Malignant Behaviors of Breast Cancer by Modulating the Global Expression and Alternative Splicing Profiles in SK‐BR‐3 Cells Through Binding mRNA

open access: yesCancer Medicine, Volume 14, Issue 10, May 2025.
GRB2 as a flexible protein and an RBP that is involved in post‐transcriptional regulation in eukaryotes, influencing all stages of mRNA synthesis, modification, splicing, and stabilization. ABSTRACT Purpose The flexible protein GRB2 interacts with HER1–4 on the cell surface and regulates the development of tumor cells; meanwhile, it is also an RBP that
Wei Liu   +6 more
wiley   +1 more source

Maf1 controls intracellular lipid accumulation and de novo lipogenesis.

open access: yes, 2014
(A) Maf1 represses intracellular lipid accumulation. Huh-7 cells infected with nsRNA (left) or Maf1 shRNA (right) were stained with Oil Red O and Mayer's Hematoxylin.
Louis Dubeau (193226)   +7 more
core   +1 more source

Comprehensive Characterization of Toxoplasma Acyl Coenzyme A-Binding Protein TgACBP2 and Its Critical Role in Parasite Cardiolipin Metabolism

open access: yesmBio, 2018
Acyl coenzyme A (CoA)-binding protein (ACBP) can bind acyl-CoAs with high specificity and affinity, thus playing multiple roles in cellular functions. Mitochondria of the apicomplexan parasite Toxoplasma gondii have emerged as key organelles for lipid ...
Yong Fu   +6 more
doaj   +1 more source

CMV2U‐Net: A U‐shaped network with edge‐weighted features for detecting and localizing image splicing

open access: yesJournal of Forensic Sciences, Volume 70, Issue 3, Page 1026-1043, May 2025.
Abstract The practice of cutting and pasting portions of one image into another, known as “image splicing,” is commonplace in the field of image manipulation. Image splicing detection using deep learning has been a hot research topic for the past few years.
Arslan Akram   +4 more
wiley   +1 more source

Maf1, repressor of tRNA transcription, is involved in the control of gluconeogenetic genes in Saccharomyces cerevisiae [PDF]

open access: yesGene, 2013
Maf1 is a negative regulator of RNA polymerase III (Pol III) in yeast. Maf1-depleted cells manifest elevated tRNA transcription and inability to grow on non-fermentable carbon source, such as glycerol. Using genomic microarray approach, we examined the effect of Maf1 deletion on expression of Pol II-transcribed genes in yeast grown in medium containing
Ewa, Morawiec   +5 more
openaire   +2 more sources

Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys

open access: yesScientific Reports, 2022
While urine-based liquid biopsy has expanded to the analyses of extracellular nucleic acids, the potential of transfer RNA (tRNA) encapsulated within extracellular vesicles has not been explored as a new class of urine biomarkers for kidney injury. Using
Hee Kyung Lee   +7 more
doaj   +1 more source

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