Results 81 to 90 of about 1,609 (154)
Maf1, repressor of tRNA transcription, is involved in the control of gluconeogenetic genes in Saccharomyces cerevisiae [PDF]
Gene, 2013 Maf1 is a negative regulator of RNA polymerase III (Pol III) in yeast. Maf1-depleted cells manifest elevated tRNA transcription and inability to grow on non-fermentable carbon source, such as glycerol. Using genomic microarray approach, we examined the effect of Maf1 deletion on expression of Pol II-transcribed genes in yeast grown in medium containing
Ewa, Morawiec +5 more
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Microbial Cell Factories, 2018 Background Geranyl acetate is widely used in the fragrance and cosmetic industries, and thus has great economic value. However, plants naturally produce a mixture of hundreds of esters, and geranyl acetate is usually only present in trace amounts, which ...
Tao Wu +4 more
doaj +1 more source
A Deep Learning Approach to Weed Eradication in Precision Agriculture
The Journal of Engineering, Volume 2025, Issue 1, January/December 2025.This study develops a deep learning framework for precise weed identification in wheat fields to enable targeted herbicide application. We evaluated six CNN architectures, with SqueezeNet emerging as the most efficient, achieving an optimal balance between high accuracy and low computational complexity.
Sarfaraz Khan Khalil +4 more
wiley +1 more source
Targeting P2X Receptors—Current Progress in Sepsis
International Journal of Inflammation, Volume 2025, Issue 1, 2025.Sepsis is defined as life‐threatening organ dysfunction caused by a dysregulated host response to infection. Inflammation, as the main pathophysiological mechanism, runs through the whole course of sepsis. Notably, P2X receptors have the capacity to mediate inflammation, nerve signaling, and thrombosis, which underscores their pivotal role in the ...
Lan Luo +6 more
wiley +1 more source
TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast
Biology Open, 2012 Summary TOR (Target Of Rapamycin) signalling coordinates cell growth and division in response to changes in the nutritional environment of the cell. TOR kinases form two distinct complexes: TORC1 and TORC2.
Wei Du +4 more
doaj +1 more source
The TOR signalling pathway in fungal phytopathogens: A target for plant disease control
Molecular Plant Pathology, Volume 25, Issue 11, November 2024.We discuss the current knowledge on the fungal TOR signalling pathway and analyse a range of disease management strategies that rely on the TOR pathway, which are expected to become a highly effective weapon for crop protection. Abstract Plant diseases caused by fungal phytopathogens have led to significant economic losses in agriculture worldwide. The
Yun Song +5 more
wiley +1 more source
Drug Delivery, 2019 In the current experimental study, we scrutinized the chemoprotective effect of astraxanthin against the 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway.
Tao Sun +4 more
doaj +1 more source
Robust repression of tRNA gene transcription during stress requires protein arginine methylation
Life Science Alliance, 2019 This work examines how protein arginine methylation of Rpc31, a subunit of RNA Pol III, promotes negative regulation of tRNA biogenesis in the context of cellular stress. Protein arginine methylation is an important means by which protein function can be
Richoo B Davis +4 more
doaj +1 more source
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Characterization of a MAF1 knockout mouse model [PDF]
, 2015 L'ARN polymérase 3 transcrit un petit groupe de gènes fortement exprimés et impliqués dans plusieurs mécanismes moléculaires. Les ARNs de transfert ou ARNt représentent plus ou moins la moitié du transcriptome de l'ARN polymérase 3. Ils sont directement impliqués dans la traduction des protéines en agissant comme transporteurs d'acides aminés qui sont ...
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