Results 71 to 80 of about 2,035 (177)

Physiological Roles for mafr-1 in Reproduction and Lipid Homeostasis

Cell Reports, 2014
Maf1 is a conserved repressor of RNA polymerase (Pol) III transcription; however, its physiological role in the context of a multicellular organism is not well understood. Here, we show that C.
Akshat Khanna, Deborah L. Johnson, Sean P. Curran   +2 more
doaj   +1 more source

Global transcriptome profiling reveals genes responding to overproduction of a small secretory, a high cysteine- and a high glycosylation-bearing protein in Yarrowia lipolytica

Biotechnology Reports, 2021
Investigation of the yeast cell’s response to recombinant secretory protein (rs-Prot) overproduction is relevant for both basic and applied research. Imbalance, overloading or stress within this process impacts the whole cell.
Paulina Korpys-Woźniak, Ewelina Celińska   +1 more
doaj   +1 more source

Phloem Proteomics to Identify Small Open Reading Frame (sORF)‐encoded Peptides With a Putative Role in the Control of Flowering Time in Arabidopsis

Physiologia Plantarum, Volume 178, Issue 2, March/April 2026.
ABSTRACT Phloem sap proteomic studies have previously revealed that phloem sap composition varies during development and upon floral induction. Specific proteins, lipids, messenger RNAs (mRNAs), and peptides have been shown to accumulate at different developmental stages.
Irene Moreno‐Sanguino, Lucía Argente Collás, Göran Samuelsson, Gunnar Wingsle, Reyes Benlloch   +4 more
wiley   +1 more source

Vocalization Characteristics of the Indo‐Pacific Humpback Dolphins (Sousa chinensis) in Xiamen Bay With Insights on Regional Differences

Ecology and Evolution, Volume 16, Issue 2, February 2026.
The Indo‐Pacific humpback dolphin population in Xiamen Bay was divided into two geographically separated but socially associated communities inhabiting the West and East sub‐regions. Based on 3 years of boat‐based surveys, this study established baseline acoustic characteristics and investigated whether vocal patterns varied with habitat conditions ...
Xuming Peng, Zhiyuan Hua, Fuxing Wu, Fei Zhang, Weijie Fu, Yupeng Li, Chuang Zhang, Wenzhan Ou, Wenjie Xiang, Bing Zhou, Zhongchang Song, Yu Zhang   +11 more
wiley   +1 more source

Mammalian Maf1 Is a Negative Regulator of Transcription by All Three Nuclear RNA Polymerases [PDF]

Molecular Cell, 2007
Most eukaryotic transcriptional regulators act in an RNA polymerase (Pol)-selective manner. Here we show that the human Maf1 protein negatively regulates transcription by all three nuclear Pols. Changes in Maf1 expression affect Pol I- and Pol III-dependent transcription in human glioblastoma lines.
Johnson, Sandra S., Zhang, Cheng, Fromm, Jody, Willis, Ian M., Johnson, Deborah L.   +4 more
openaire   +2 more sources

MAF1 loss protects against ischemic cerebral injury by attenuating NLRP3-mediated pyroptosis

Brain Research Bulletin
Background: Acute ischemic stroke (AIS) is the second leading cause of death worldwide and is associated with high rates of disability and mortality.
Xue Gao, Hanzhi Wang, Lingting Jin, Shumeng Li, Gang Li, Can Cui, Yingying Han   +6 more
doaj   +1 more source

Multiobjective Optimization for Torsional Stiffness of Antiroll Bar on Trucks

Shock and Vibration, Volume 2026, Issue 1, 2026.
The antiroll bar (ARB) plays an important role in reducing the rollover phenomenon and uneven load distribution between the wheels on an axle, thus enhancing the safety and roll stability of vehicles. This study proposes a method for optimizing the torsional stiffness of the ARB on trucks, with three main objectives: (1) building a general model of a ...
Ngo Van Dung, Van Tan Vu, Truong Manh Hung, Do Trong Tu, Marco Civera   +4 more
wiley   +1 more source

Deep Learning Approach for Accurate Segmentation of Sand Boils in Levee Systems

IEEE Access, 2023
Sand boils can contribute to the liquefaction of a portion of the levee, leading to levee failure. Accurately detecting and segmenting sand boils is crucial for effectively monitoring and maintaining levee systems.
Manisha Panta, Md. Tamjidul Hoque, Kendall N. Niles, Joe Tom, Mahdi Abdelguerfi, Maik Falanagin   +5 more
doaj   +1 more source

Maf1 phosphorylation is regulated through the action of prefoldin-like Bud27 on PP4 phosphatase in Saccharomyces cerevisiae. [PDF]

Nucleic Acids Res
International audienceBud27 is a prefoldin-like protein that participates in transcriptional regulation mediated by the three RNA polymerases in Saccharomyces cerevisiae.
Gutiérrez-Santiago F, Martínez-Fernández V, Garrido-Godino AI, Colino-Palomino C, Clemente-Blanco A, Conesa C, Acker J, Navarro F.   +7 more
europepmc   +2 more sources

Evaluating the Negative‐Strand Coding Potential in Plum Pox Virus

Molecular Plant Pathology, Volume 26, Issue 12, December 2025.
Plum pox virus produces two polyproteins from ORFs in the positive strand. This study explores the possible expression of peptides from negative‐strand ORFs (rORFs). ABSTRACT Recent studies proposed that the negative strands of some single‐stranded, positive‐sense RNA viruses contain reverse open reading frames (rORFs) that encode functional peptides ...
Beatriz García, José Vicente Del Álamo, Mario Rincón, Irene Gonzalo, Xiaofei Cheng, Juan Antonio García, Carmen Simón‐Mateo, Adrián A. Valli, Bernardo Rodamilans   +8 more
wiley   +1 more source