Results 71 to 80 of about 1,609 (154)
ABSTRACT Genomic selection (GS) and genome‐wide association studies (GWAS) have not been investigated in Vietnamese dairy cattle, even for basic milk production traits, largely due to the scarcity of individual phenotype recording in smallholder dairy farms (SDFs).
Nguyen N. Bang +6 more
wiley +1 more source
Acyl coenzyme A (CoA)-binding protein (ACBP) can bind acyl-CoAs with high specificity and affinity, thus playing multiple roles in cellular functions. Mitochondria of the apicomplexan parasite Toxoplasma gondii have emerged as key organelles for lipid ...
Yong Fu +6 more
doaj +1 more source
Circadian Control of Protein Synthesis
The circadian clock maintains proteostasis in part through rhythmic control of protein synthesis. We propose that, across the day, translation alternates between distinct mechanisms to optimize energy efficiency and regulate complex assembly. This temporal compartmentalization produces alternating phases of slow specialized translation and rapid ...
Nathan R. James, John S. O'Neill
wiley +1 more source
Maf1 Is an Essential Mediator of Diverse Signals that Repress RNA Polymerase III Transcription [PDF]
Maf1 is a putative repressor of RNA polymerase (pol) III transcription that is conserved from yeast to humans. Here we show that Maf1 is a common component of multiple signaling pathways in S. cerevesiae that sense changes in the cellular environment and repress pol III transcription.
Upadhya, Rajendra +2 more
openaire +2 more sources
While urine-based liquid biopsy has expanded to the analyses of extracellular nucleic acids, the potential of transfer RNA (tRNA) encapsulated within extracellular vesicles has not been explored as a new class of urine biomarkers for kidney injury. Using
Hee Kyung Lee +7 more
doaj +1 more source
MaOAOA: A Novel Many‐Objective Arithmetic Optimization Algorithm for Solving Engineering Problems
MaOAOA introduces an innovative many‐objective optimization framework combining an Information Feedback Mechanism, reference point‐based selection, and niche preservation strategies. Its effectiveness surpasses leading algorithms in convergence, diversity, and computational efficiency across benchmark and real‐world engineering problems, establishing ...
Pradeep Jangir +5 more
wiley +1 more source
Diet influences tRNA modifications and metabolism. Metabolic processes are essential for the synthesis of many tRNA modifications, which can impact metabolism by altering mRNA translation and bioenergetics pathways. We discuss the importance of studying tRNA modifications from the viewpoint of cellular metabolism to fully grasp the complexity of ...
Sherif Rashad, Aseel Marahleh
wiley +1 more source
An Adaptive Reference Vector Adjustment Strategy and Improved Angle-Penalized Value Method for RVEA
Decomposition-based evolutionary multiobjective algorithms (MOEAs) divide a multiobjective problem into several subproblems by using a set of predefined uniformly distributed reference vectors and can achieve good overall performance especially in ...
Wenbo Qiu +4 more
doaj +1 more source
The role of acetylation and deacetylation in cancer metabolism
Protein acetylation and deacetylation influence metabolic reprogramming in tumour cells by regulating the function and activity of various signalling pathways, transcription factors and metabolic enzymes. Abstract As a hallmark of cancer, metabolic reprogramming adjusts macromolecular synthesis, energy metabolism and redox homeostasis processes to ...
Cuicui Wang, Xiaoxin Ma
wiley +1 more source
maf1 mutation alters the subcellular localization of the Mod5 protein in yeast.
Two forms of Mod5p, a tRNA modification enzyme, are found in three intracellular compartments, mitochondria, cytoplasm and nucleus, but are encoded by a single MOD5 gene. The two forms of the enzyme, Mod5p-I and Mod5p-II differ at the N-termini and are produced by initiation of translation at different start codons. Mod5p-I does contain a mitochondrial
M, Murawski +5 more
openaire +3 more sources

