Results 61 to 70 of about 2,035 (177)

Differential Phosphorylation of RNA Polymerase III and the Initiation Factor TFIIIB in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2015
The production of ribosomes and tRNAs for protein synthesis has a high energetic cost and is under tight transcriptional control to ensure that the level of RNA synthesis is balanced with nutrient availability and the prevailing environmental conditions.
Jaehoon Lee, Robyn D Moir, Ian M Willis
doaj   +1 more source

RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification.

PLoS Genetics, 2015
Control of the differential abundance or activity of tRNAs can be important determinants of gene regulation. RNA polymerase (RNAP) III synthesizes all tRNAs in eukaryotes and it derepression is associated with cancer.
Aneeshkumar G Arimbasseri, Nathan H Blewett, James R Iben, Tek N Lamichhane, Vera Cherkasova, Markus Hafner, Richard J Maraia   +6 more
doaj   +1 more source

CRISPR/Cas9‐Mediated Knockout of LbSP1 and LbSP5G1 Reveals Efficient Customization of Shoot Architecture in Black Goji Berry

Plant Biotechnology Journal, EarlyView.
ABSTRACT Goji is recognized as a nutritionally rich superfruit with medicinal and industrial importance. However, its inherently indeterminate growth habit causes asynchronous flowering and uneven fruit ripening, resulting in harvesting inefficiency with high labour costs and low fruit yield.
Fazal Rehman, Huanfang Liu, Yun Ma, Shaohua Zeng, Yan Wu, Yuan Zong, Chao Yang, Ying Wang   +7 more
wiley   +1 more source

Maf1 occupies the FASN promoter to repress lipogenic gene expression.

, 2014
(A) Maf1 negatively regulates cellular FASN and ACC1 protein expression. Protein lysates isolated from Huh7 cells stably infected with nsRNA or Maf1 shRNAs (left) or HepG2 cells engineered to express doxycycline-inducible Maf1-HA as described in Fig.
Louis Dubeau (193226), Bangyan L. Stiles (562564), Aarti D. Rohira (673046), Beth M. Palian (673045), Sandra A. S. Johnson (673047), Ni Zheng (332084), Lina He (257060), Deborah L. Johnson (673048)   +7 more
core   +1 more source

Polymerase II–Associated Factor 1 Complex-Regulated FLOWERING LOCUS C-Clade Genes Repress Flowering in Response to Chilling

Frontiers in Plant Science, 2022
RNA polymerase II–associated factor 1 complex (PAF1C) regulates the transition from the vegetative to the reproductive phase primarily by modulating the expression of FLOWERING LOCUS C (FLC) and FLOWERING LOCUS M [FLM, also known as MADS AFFECTING ...
Zeeshan Nasim, Hendry Susila, Suhyun Jin, Geummin Youn, Ji Hoon Ahn   +4 more
doaj   +1 more source

The SVP–FRO6 Module Integrates the Control of Leaf Senescence and Flowering in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 9, Page 7191-7209, September 2026.
ABSTRACT Plants coordinate major developmental transitions by integrating intrinsic genetic programs with environmental signals, where nutrient availability serves as a critical external factor shaping growth and fitness. Iron (Fe), an essential micronutrient for cellular respiration and photosynthesis, is strictly regulated through sophisticated ...
Hyunsu Park, Yeong Seon Yoon, Sanghoon Park, Ukcheol Jeong, Hyeyoung Choi, Hyunwoo Oh, Dovran Shamamedov, Zhonghai Li, Hye Ryun Woo   +8 more
wiley   +1 more source

Crystal Structure and Regulation of the Citrus Pol III Repressor MAF1 by Auxin and Phosphorylation [PDF]

Structure, 2017
MAF1 is the main RNA polymerase (Pol) III repressor that controls cell growth in eukaryotes. The Citrus ortholog, CsMAF1, was shown to restrict cell growth in citrus canker disease but its role in plant development and disease is still unclear. We solved the crystal structure of the globular core of CsMAF1, which reveals additional structural elements ...
Santos Soprano, Adriana, Oliveira de Giuseppe, Priscila, Massayoshi Shimo, Hugo, Brenelli Lima, Tatiani, Heleno Batista, Fernanda Aparecida, Lima Righetto, Germanna, Carvalho Pereira, José Geraldo de, Campos Granato, Daniela, Ziem Nascimento, Andrey Fabricio, Cesar Gozzo, Fabio, Lopesde Oliveira, Paulo Sérgio, Migliorini Figueira, Ana Carolina, Costa Smetana, Juliana Helena, Franco Paes Leme, Adriana, Murakami, Mario Tyago, Benedetti, Celso Eduardo   +15 more
openaire   +3 more sources

Metabolic Reprogramming and Exosome Remodeling in an Ndufs4‐Deficient Model of Leigh Syndrome

iNew Medicine, Volume 2, Issue 2, June 2026.
Ndufs4 knockout drives exosomal remodeling, reprograms cellular metabolism, impairs neural stem cell self‐renewal and differentiation, and suppresses mTOR signaling, providing a conceptual framework for understanding Leigh syndrome pathogenesis and informing therapeutic development.
Yakun Liu, Zhi Yang, Zhencai Xing, Rongrong Zhao, Yixuan Zhou, Xue Yang, Jicheng Zhu, Shuo Chen, Yuhang Zhang, Mengxue Xu, Xiang Kong, Minqiong Sun, Zhenya Tan, Hong Zheng   +13 more
wiley   +1 more source

Network and enrichment analysis of MAF1.

, 2023
(A) Using String 11.5 [80] we identified protein-protein interactions (PPI) for MAF1. The PPI enrichment p-value B) Table of protein interaction scores, interaction score > 0.4 was applied. (TIF)
Gabriella Olshefsky (17108682), Stephanie Cabarcas-Petroski (9631636), Laura Schramm (73396)   +2 more
core   +1 more source

Maf1, repressor of RNA polymerase III, indirectly affects tRNA processing [PDF]

, 2011
Maf1 is negative regulator of RNA polymerase III in yeast. We observed high levels of both primary transcript and end-matured, intron-containing pre-tRNAs in the maf1∆ strain.
Towpik, Joanna, Boguta, Magdalena, Turowski, Tomasz W., Karkusiewicz, Iwona, Graczyk, Damian   +4 more
core   +1 more source