Results 61 to 70 of about 1,593 (136)
Scientific Reports, 2022 While urine-based liquid biopsy has expanded to the analyses of extracellular nucleic acids, the potential of transfer RNA (tRNA) encapsulated within extracellular vesicles has not been explored as a new class of urine biomarkers for kidney injury. Using
Hee Kyung Lee +7 more
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Maf1, repressor of tRNA transcription, is involved in the control of gluconeogenetic genes in Saccharomyces cerevisiae [PDF]
Gene, 2013 Maf1 is a negative regulator of RNA polymerase III (Pol III) in yeast. Maf1-depleted cells manifest elevated tRNA transcription and inability to grow on non-fermentable carbon source, such as glycerol. Using genomic microarray approach, we examined the effect of Maf1 deletion on expression of Pol II-transcribed genes in yeast grown in medium containing
Ewa, Morawiec +5 more
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An Adaptive Reference Vector Adjustment Strategy and Improved Angle-Penalized Value Method for RVEA
Complexity, 2021 Decomposition-based evolutionary multiobjective algorithms (MOEAs) divide a multiobjective problem into several subproblems by using a set of predefined uniformly distributed reference vectors and can achieve good overall performance especially in ...
Wenbo Qiu +4 more
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maf1 mutation alters the subcellular localization of the Mod5 protein in yeast.
Acta Biochimica Polonica, 1994 Two forms of Mod5p, a tRNA modification enzyme, are found in three intracellular compartments, mitochondria, cytoplasm and nucleus, but are encoded by a single MOD5 gene. The two forms of the enzyme, Mod5p-I and Mod5p-II differ at the N-termini and are produced by initiation of translation at different start codons. Mod5p-I does contain a mitochondrial
M, Murawski +5 more
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Maf1 Is an Essential Mediator of Diverse Signals that Repress RNA Polymerase III Transcription [PDF]
Molecular Cell, 2002 Maf1 is a putative repressor of RNA polymerase (pol) III transcription that is conserved from yeast to humans. Here we show that Maf1 is a common component of multiple signaling pathways in S. cerevesiae that sense changes in the cellular environment and repress pol III transcription.
Upadhya, Rajendra +2 more
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TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast
Biology Open, 2012 Summary TOR (Target Of Rapamycin) signalling coordinates cell growth and division in response to changes in the nutritional environment of the cell. TOR kinases form two distinct complexes: TORC1 and TORC2.
Wei Du +4 more
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Microbial Cell Factories, 2018 Background Geranyl acetate is widely used in the fragrance and cosmetic industries, and thus has great economic value. However, plants naturally produce a mixture of hundreds of esters, and geranyl acetate is usually only present in trace amounts, which ...
Tao Wu +4 more
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Drug Delivery, 2019 In the current experimental study, we scrutinized the chemoprotective effect of astraxanthin against the 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway.
Tao Sun +4 more
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Characterization of a MAF1 knockout mouse model [PDF]
, 2015 L'ARN polymérase 3 transcrit un petit groupe de gènes fortement exprimés et impliqués dans plusieurs mécanismes moléculaires. Les ARNs de transfert ou ARNt représentent plus ou moins la moitié du transcriptome de l'ARN polymérase 3. Ils sont directement impliqués dans la traduction des protéines en agissant comme transporteurs d'acides aminés qui sont ...
openaire
Robust repression of tRNA gene transcription during stress requires protein arginine methylation
Life Science Alliance, 2019 This work examines how protein arginine methylation of Rpc31, a subunit of RNA Pol III, promotes negative regulation of tRNA biogenesis in the context of cellular stress. Protein arginine methylation is an important means by which protein function can be
Richoo B Davis +4 more
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