ECONOMIC POTENTIAL FOR PROMOTION OF EGYPTIAN ONIONS EXPORTS [PDF]
Through study of major maf1(ets of Egyptian onions exports and the prevalent innuential factors, promotion potentials were investigated. The studY~Showed winter onions as the principal onions exports of which the Arab Gulf Cooperati n bloc Imports shar~
Laila EL-shraif,
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Two Steps in Maf1-dependent Repression of Transcription by RNA Polymerase III [PDF]
In Saccharomyces cerevisiae, Maf1 is essential for mediating the repression of transcription by RNA polymerase (pol) III in response to diverse cellular conditions. These conditions activate distinct signaling pathways that converge at or above Maf1. Thus, Maf1-dependent repression is thought to involve a common set of downstream inhibitory effects on ...
Neelam, Desai +5 more
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Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes [PDF]
RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA. The originally defined yeast Pol III transcriptome appears to be expanding owing to the application of new methods.
Ewa Leśniewska, Magdalena Boguta
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Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila. [PDF]
The small G-protein Ras is a conserved regulator of cell and tissue growth. These effects of Ras are mediated largely through activation of a canonical RAF-MEK-ERK kinase cascade.
Shrivani Sriskanthadevan-Pirahas +3 more
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Mycobacterium africanum is an important cause of tuberculosis (TB) in West Africa. So far, two lineages called M. africanum West African 1 (MAF1) and M. africanum West African 2 (MAF2) have been defined.
Florian Gehre +7 more
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Maf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription [PDF]
RNA polymerase III (Pol III) produces essential components of the biosynthetic machinery, and therefore its activity is tightly coupled with cell growth and metabolism. In the yeast Saccharomyces cerevisiae, Maf1 is the only known global and direct Pol III transcription repressor which mediates numerous stress signals.
Małgorzata, Cieśla +9 more
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RNA Polymerase III, Ageing and Longevity
Transcription in eukaryotic cells is performed by three RNA polymerases. RNA polymerase I synthesises most rRNAs, whilst RNA polymerase II transcribes all mRNAs and many non-coding RNAs. The largest of the three polymerases is RNA polymerase III (Pol III)
Yavuz Kulaberoglu +5 more
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Loss of the RNA polymerase III repressor MAF1 confers obesity resistance [PDF]
MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. Here we show that a whole-body knockout of Maf1
Bonhoure Nicolas +19 more
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The C-Box Region of MAF1 Regulates Transcriptional Activity and Protein Stability [PDF]
MAF1 is a conserved negative regulator of RNA polymerase (pol) III and intracellular lipid homeostasis across species. Here, we show that the MAF1 C-box region negatively regulates its activity. Mutations in Caenorhabditis elegans mafr-1 that truncate the C-box retain the ability to inhibit the transcription of RNA pol III targets, reduce lipid ...
Ajay, Pradhan +3 more
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Differential Phosphorylation of RNA Polymerase III and the Initiation Factor TFIIIB in Saccharomyces cerevisiae. [PDF]
The production of ribosomes and tRNAs for protein synthesis has a high energetic cost and is under tight transcriptional control to ensure that the level of RNA synthesis is balanced with nutrient availability and the prevailing environmental conditions.
Jaehoon Lee, Robyn D Moir, Ian M Willis
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