Results 51 to 60 of about 1,593 (136)
RNA polymerase II–associated factor 1 complex (PAF1C) regulates the transition from the vegetative to the reproductive phase primarily by modulating the expression of FLOWERING LOCUS C (FLC) and FLOWERING LOCUS M [FLM, also known as MADS AFFECTING ...
Zeeshan Nasim +4 more
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Investigation of the yeast cell’s response to recombinant secretory protein (rs-Prot) overproduction is relevant for both basic and applied research. Imbalance, overloading or stress within this process impacts the whole cell.
Paulina Korpys-Woźniak +1 more
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Physiological Roles for mafr-1 in Reproduction and Lipid Homeostasis
Maf1 is a conserved repressor of RNA polymerase (Pol) III transcription; however, its physiological role in the context of a multicellular organism is not well understood. Here, we show that C.
Akshat Khanna +2 more
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Regulation of RNA polymerase III transcription by Maf1 protein.
Maf1 was the first protein discovered to regulate polymerase III RNA in yeast and because it is evolutionarily conserved, a Maf1 ortholog also serves to restrain transcription in mouse and human cells. Understanding the mechanism of the regulation has been made possible by recent studies showing that Maf1 is a nuclear/cytoplasmic protein whose ...
Małgorzata, Cieśla, Magdalena, Boguta
openaire +3 more sources
Mammalian Maf1 Is a Negative Regulator of Transcription by All Three Nuclear RNA Polymerases [PDF]
Most eukaryotic transcriptional regulators act in an RNA polymerase (Pol)-selective manner. Here we show that the human Maf1 protein negatively regulates transcription by all three nuclear Pols. Changes in Maf1 expression affect Pol I- and Pol III-dependent transcription in human glioblastoma lines.
Johnson, Sandra S. +4 more
openaire +2 more sources
Deep Learning Approach for Accurate Segmentation of Sand Boils in Levee Systems
Sand boils can contribute to the liquefaction of a portion of the levee, leading to levee failure. Accurately detecting and segmenting sand boils is crucial for effectively monitoring and maintaining levee systems.
Manisha Panta +5 more
doaj +1 more source
MAF1 loss protects against ischemic cerebral injury by attenuating NLRP3-mediated pyroptosis
Background: Acute ischemic stroke (AIS) is the second leading cause of death worldwide and is associated with high rates of disability and mortality.
Xue Gao +6 more
doaj +1 more source
Sub1 and Maf1, two effectors of RNA polymerase III, are involved in the yeast quiescence cycle.
Sub1 and Maf1 exert an opposite effect on RNA polymerase III transcription interfering with different steps of the transcription cycle. In this study, we present evidence that Sub1 and Maf1 also exhibit an opposite role on yeast chronological life span ...
Joël Acker +5 more
doaj +1 more source
Copy Number Variation Discovery in South African Nguni-Sired and Bonsmara-Sired Crossbred Cattle
Crossbreeding forms part of Climate-Smart beef production and is one of the strategies to mitigate the effects of climate change. Two Nguni-sired and three Bonsmara-sired crossbred animals underwent whole genome sequencing.
Bhaveni B. Kooverjee +4 more
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Acyl coenzyme A (CoA)-binding protein (ACBP) can bind acyl-CoAs with high specificity and affinity, thus playing multiple roles in cellular functions. Mitochondria of the apicomplexan parasite Toxoplasma gondii have emerged as key organelles for lipid ...
Yong Fu +6 more
doaj +1 more source

