Results 51 to 60 of about 3,186 (156)

Endocannabinoid Metabolism and Traumatic Brain Injury

Cells, 2021
Traumatic brain injury (TBI) represents a major cause of morbidity and disability and is a risk factor for developing neurodegenerative diseases, including Alzheimer’s disease (AD).
Dexiao Zhu, Fei Gao, Chu Chen
doaj   +1 more source

An α/β‐Hydrolase GmABHD6 Controls Seed Oil Content and Yield in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed oil content is a key trait in soybean, yet its genetic basis remains largely unresolved. Here, we identify GmABHD6, an α/β‐hydrolase domain‐containing gene, as the causal gene underlying a major quantitative trait locus (QTL) for seed oil content on chromosome 16.
Kaixin Yu, Limin Hu, Bo Sun, Zehao Chen, Xu Li, Shiyu Zhang, Huilin Tian, Wenjing Zhang, Shimin Ren, Xue Han, Chang Xu, Siming Wei, Mingliang Yang, Fanjiang Kong, Qingshan Chen, Zhaoming Qi   +15 more
wiley   +1 more source

The anti-inflammatory and analgesic potential of the probiotic Streptococcus thermophilus via inhibition of endocannabinoid-degrading enzymes: a preliminary in vitro study [PDF]

Exploration of Immunology
Aim: The benefit of topical application of probiotics on pain and itching associated with skin disorders has become an increasingly intriguing topic in recent years.
Serena Altamura, Elona Dybeli, Francesca Lombardi, Paola Palumbo, Francesca Rosaria Augello, Skender Topi, Maria Grazia Cifone, Benedetta Cinque   +7 more
doaj   +1 more source

Inhibition of Monoacylglycerol Lipase Decreases Angiogenic Features of Endothelial Cells via Release of Tissue Inhibitor of Metalloproteinase-1 from Lung Cancer Cells

Cells, 2023
Despite the well-described anticarcinogenic effects of endocannabinoids, the influence of the endocannabinoid system on tumor angiogenesis is still debated.
Felix Wittig, Lino Henkel, Jan Lukas Prüser, Jutta Merkord, Robert Ramer, Burkhard Hinz   +5 more
doaj   +1 more source

Exploring the Therapeutic Potential of Cannabidiol in Cutaneous Squamous Cell Carcinoma: An Integrated Computational and Experimental Study

International Journal of Quantum Chemistry, Volume 126, Issue 5, March 5, 2026.
Cannabidiol (CBD) exhibits increased reactivity, stronger CB1 receptor binding, and enhanced cytotoxicity against A431 squamous carcinoma cells compared to 5‐fluorouracil (5‐FU). Integrated DFT, molecular docking, and experimental analyses demonstrate CBD's improved stability and binding affinity, highlighting its potential as an alternative ...
Andrea Jess Josiah, Krishna Kuben Govender, Penny Poomani Govender, Werner Cordier, Margo Nell, Suprakas Sinha Ray   +5 more
wiley   +1 more source

单酰基甘油脂肪酶在子宫内膜癌中作用机制的研究进展

Zhongguo shiyan zhenduanxue, 2020
单酰基甘油脂肪酶（MAGL）是一种重要的脂代谢酶,它主要在脂类的分解和代谢途径中发挥效用,通过水解单酰基甘油,从而产生游离脂肪酸（FFAs）[1-3]。研究表明[4]MAGL在肿瘤的进展中拥有不可忽视的调节作用,假如将MAGL敲低,肿瘤细胞的增殖显然也表现出被抑制的结果。根据女性生殖道肿瘤中MAGL的表达特点,本文就MAGL在子宫内膜恶性肿瘤中的表达以及MAGL对癌细胞生长的影响的研究成果予以综述。
姜莹, 刘爱民
doaj  

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

New Phytologist, Volume 249, Issue 5, Page 2196-2214, March 2026.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri, Sean T. McGuire, Matthew G. Garneau, Niña Alyssa M. Barroga, Philip D. Bates   +4 more
wiley   +1 more source

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, Volume 11, Issue 1, Page 347-362, February 2026.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Mamilice kao prodavanje magle

Medijske studije
U ovom su radu prikazani stavovi hrvatskih novinara i urednika o mamilicama na temelju po‎lustrukturiranih intervjua provedenih 2023. godine s urednicima i novinarima trojih najčitanijih hrvatskih ‎dnevnih novina, koje imaju i svoje mrežne portale – Jutarnji list, Večernji list i 24sata. Istraživanje je poka‎zalo kako su financijska nužnost i povećanje
Stela Lechpammer, Igor Kanižaj, Boris Beck   +2 more
openaire   +2 more sources

Climatology of Cloud‐Land‐Surface Coupling Across Different ARM Sites

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 1, 16 January 2026.
Abstract Land‐atmosphere interactions play a critical role in the evolution and formation of low‐level clouds. The different states of coupling between low‐level clouds and the surface are uncertain, primarily over continental regions, where complex thermodynamics complicates their investigation.
Natalia Roldán‐Henao, Tianning Su, Zhanqing Li, Youtong Zheng, John Yorks   +4 more
wiley   +1 more source