Results 141 to 150 of about 7,761 (187)

Single-cell profiling reveals CCL5Hi GZMAHi effector memory CD8 T cell association to oligoarticular JIA. [PDF]

open access: yesRheumatology (Oxford)
Lopez-Corbeto M   +9 more
europepmc   +1 more source

MAIT cell responses to S. aureus and sensitivity to HlgAB are modulated by activation and tissue-dependent virulence effects

open access: yes
Raineri EJM   +31 more
europepmc   +1 more source

MAIT Cells in Health and Disease

Annual Review of Immunology, 2020
Mucosal-associated invariant T (MAIT) cells have been attracting increasing attention over the last few years as a potent unconventional T cell subset. Three factors largely account for this emerging interest. Firstly, these cells are abundant in humans, both in circulation and especially in some tissues such as the liver.
Nicholas M Provine, Paul Klenerman
exaly   +3 more sources

MAIT cells and viruses [PDF]

open access: yesImmunology and Cell Biology, 2018
AbstractMucosal associated invariant T cells (MAIT cells) bear a T cell receptor (TCR) that specifically targets microbially derived metabolites. Functionally, they respond to bacteria and yeasts, which possess the riboflavin pathway, essential for production of such metabolites and which are presented on MR1.
Christian B Willberg   +2 more
exaly   +3 more sources

MAIT cells in infectious diseases

Current Opinion in Immunology, 2017
In humans, MAIT cells represent the most abundant T cell subset reacting against bacteria. Their frequency in the blood is decreased in a large variety of infectious diseases of either bacterial or viral origin. MAIT cells accumulate at the site of bacterial infection and are protective in experimental infection models.
Marion, Salou   +2 more
openaire   +2 more sources

MAIT cell subtypes in multiple sclerosis

Journal of Neuroimmunology, 2020
In patients with multiple sclerosis (MS) and healthy controls (HC) we studied circulating MAIT cells and MAIT cell subtypes expressing CXCR3 and CCR6 by flow cytometry. Absolute numbers of MAIT cells and specifically Tc17-like MAIT cells were lower in patients with primary progressive MS (PPMS) than in controls. Low numbers of Tc17-like MAIT cells were
Ammitzbøll, Cecilie   +5 more
openaire   +3 more sources

MAIT cell development in mice and humans

Molecular Immunology, 2021
MAIT cells arise in the thymus following rearrangement of a T cell receptor (TCR) reactive against microbial vitamin B2-derived metabolites presented by the MHC-Ib molecule, MR1. Mechanisms that are conserved in mammals ensure the frequent production of MR1-restricted TCRs and the intra-thymic differentiation of MR1-restricted thymocytes into effector ...
Marion, Salou   +2 more
openaire   +2 more sources

MAITS

2007
In this chapter, we propose a multi-agent-based information technology (IT) security approach (MAITS) as a holistic solution to the increasing needs of securing computer systems. Each specialist task for security requirements is modeled as a specialist agent.
openaire   +1 more source

Role of MAIT cells in metabolic diseases

Molecular Immunology, 2021
MAIT cells are innate-like T cells that are enriched in mucosal sites and tissues including adipose tissue and liver. They play an important role in immunity against microbial pathogens. Recently, it has been reported that MAIT cells could also be important in metabolic diseases and can be involved in setting up and maintaining chronic inflammation. In
Amine, Toubal, Agnès, Lehuen
openaire   +2 more sources

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