Results 121 to 130 of about 12,530 (222)

Mucosal-Associated Invariant T Cells in Autoimmune Diseases

Frontiers in Immunology, 2018
Mucosal-associated invariant T (MAIT) cells are innate T cells restricted by MHC-related molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in humans and TRAV1-TRAJ33 in mice.
Asako Chiba, Goh Murayama, Sachiko Miyake   +2 more
doaj   +1 more source

CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy

Journal of Experimental & Clinical Cancer Research
Background Mucosal-associated invariant T (MAIT) cells have been reported to regulate tumor immunity. However, the immune characteristics of MAIT cells in non-small cell lung cancer (NSCLC) and their correlation with the treatment efficacy of immune ...
Jingjing Qu, Binggen Wu, Lijun Chen, Zuoshi Wen, Liangjie Fang, Jing Zheng, Qian Shen, Jianfu Heng, Jianya Zhou, Jianying Zhou   +9 more
doaj   +1 more source

Estrogen Induced Regulation of Mucosal-Associated Invariant T Cells in Asthma

Journal of Immunology Research
Asthma affects over 300 million people worldwide, with increasing rates annually. Males have higher asthma prevalence in adolescence, while females exhibit higher rates in adulthood. Reduced mucosal-associated invariant T (MAIT) cells are found in severe
Shubhanshi Trivedi, Samuel E. Aamodt, Thomas P. Huecksteadt, Elizabeth J. Myers, Grace Helen McGee, Jackson G. Cacioppo, Jeffrey Aubé, Robert Paine, Daniel T. Leung, Kristi J. Warren   +9 more
doaj   +1 more source

Potential of MAIT cells to modulate asthma

Allergology International
Despite recent advances in asthma treatments, the search for novel therapies remains necessary because there are still patients with recurrent asthma exacerbations and poor responses to the existing treatments. Since group 2 innate lymphoid cells (ILC2) play a pivotal role in asthma by triggering and exacerbating type 2 inflammation, controlling ILC2s ...
Yasuo Shimizu, Chie Sugimoto, Hiroshi Wakao   +2 more
openaire   +3 more sources

High pre-transplant Mucosal Associated Invariant T Cell (MAIT) count predicts favorable course of myeloid aplasia

Biomedical Papers
Aims. Mucosal Associated Invariant T (MAIT) cells are unconventional T cells with anti-infective potential. MAIT cells detect and fight against microbes on mucosal surfaces and in peripheral tissues.
Ivana Karlova Zubata, Jitka Smetanova Brozova, Tomas Karel, Barbora Bacova, Jan Novak   +4 more
doaj   +1 more source

Mucosal-Associated Invariant T (MAIT) cells are impaired in Th17 associated primary and secondary immunodeficiencies

The recently described Mucosal Associated Invariant T (MAIT) cells mediate specific recognition of bacterial and fungal vitamin B2 metabolites. As innate T cells, they possess broad effector responses, including IFN- including Iproduction, that are ...
Barcenas-Morales, Gabriela, Döffinger, Rainer, Eren, Efrem, Faust, Saul N., Gao, Yifang, Ottensmeier, Christian H., Rae, William, Ramakrishnan, Keseva, Williams, Anthony P.   +8 more
core   +1 more source

Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy [PDF]

, 2015
HIV infection profoundly affects many parameters of the immune system and ultimately leads to AIDS, yet which factors are most important for determining resistance, pathology, and response to antiretroviral treatment - and how best to monitor them ...
Best, K, Chain, B, Friedman, N, Gray, ER, Heather, JM, Noursadeghi, M, Oakes, T, Roe, JK, Thomas, N   +8 more
core  

The role of vitamin D3 and vitamin B9 (Folic acid) in immune system [PDF]

, 2016
Background and aims: Vitamins are essential constituents of our diet that Longley have been known to influence the immune system. Vitamin D3 and B9 have received particular attention in recent years as these vitamins have been shown to have an unexpected
Mansourabadi, Amir Hossein., Mansouri, Reza., Moogooei, Maryam., Moogooei, Mozhgan., Razavi, Nastaran.   +4 more
core   +1 more source

Optimization of armored spherical tanks for storage on the lunar surface [PDF]

A redundancy strategy for reducing micrometeroid armoring mass is investigated, with application to cryogenic reactant storage for a regenerative fuel cell (RFC) on the lunar surface.
Bents, D. J., Knight, D. A.
core   +1 more source

MAIT Cells in Liver Disease. [PDF]

Cells
Azad AI, Gutierrez F, Gores GJ.
europepmc   +1 more source