Results 111 to 120 of about 8,261 (205)

CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy

Journal of Experimental & Clinical Cancer Research
Background Mucosal-associated invariant T (MAIT) cells have been reported to regulate tumor immunity. However, the immune characteristics of MAIT cells in non-small cell lung cancer (NSCLC) and their correlation with the treatment efficacy of immune ...
Jingjing Qu, Binggen Wu, Lijun Chen, Zuoshi Wen, Liangjie Fang, Jing Zheng, Qian Shen, Jianfu Heng, Jianya Zhou, Jianying Zhou   +9 more
doaj   +1 more source

Insights Into Mucosal-Associated Invariant T Cell Biology From Studies of Invariant Natural Killer T Cells

Frontiers in Immunology, 2018
Mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells are innate-like T cells that function at the interface between innate and adaptive immunity.
Lucy C. Garner, Paul Klenerman, Paul Klenerman, Nicholas M. Provine   +3 more
doaj   +1 more source

MAIT cells in HD, FMS, RA, and SpA.

, 2015
A, Representative FACS profile of MAIT cells and NKG2D expression in total, CD8+, and DN MAIT cells in PBMC from a FMS patient. The number in the figure shows the percentage of the populations. MAIT cells are defined as Vα7.2+CD161high within CD3+ cells.
Takahiko Konno (719061), Rika Wakao (719062), Chie Sugimoto (245505), Hiroyoshi Fujita (719063), Hiroko Fujita (715453), Hiroshi Wakao (719064)   +5 more
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Mucosal-Associated Invariant T Cells in Autoimmune Diseases

Frontiers in Immunology, 2018
Mucosal-associated invariant T (MAIT) cells are innate T cells restricted by MHC-related molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in humans and TRAV1-TRAJ33 in mice.
Asako Chiba, Goh Murayama, Sachiko Miyake   +2 more
doaj   +1 more source

The antimicrobial role of human MAIT cells

, 2021
MAIT cells are unconventional T cells that have characteristics of both innate and adaptive immunity. Their fast mobilization and wide distribution in tissues make them part of the first line of defense against infection.
Caroline Boulouis (18658708)
core  

MAIT cells in T1D patients

, 2019
Le diabète de type 1 (DT1) est une maladie auto-immune caractérisée par l'implication du système immunitaire adaptatif mais également inné. Des altérations de l'homéostasie intestinale sont également décrites. Les cellules MAIT appartiennent à la famille
Nel, Isabelle
core  

Liver transplant-facilitated CD161+Vα7.2+ MAIT cell recovery demonstrates clinical benefits in hepatic failure patients

Nature Communications
Mucosal-associated invariant T (MAIT) cells exert multifaceted effects such as anti-microbial activity, tissue repair, and pro-fibrotic effects across various disease settings. Nonetheless, their role in liver injury and hemostasis remains debated. Here,
Wei Wang, Chen Dai, Peng Zhu, Mi Wu, Haoquan Zhang, Qing Wei, Ting Zhou, Xiaosheng Tan, Ying Jiang, Xue Cheng, Zhihui Liang, Xiongwen Wu, Zhishui Chen, Xiufang Weng   +13 more
doaj   +1 more source

CD8 MAIT cells gradually recover with ART in HIV+ children.

, 2016
(A) CD8+ MAIT cells in ART- children before (pre-ART) and 10–21 months after ART initiation (post-ART). (B) CD8+ MAIT cells in ART+ children at baseline (T0) and at 10–21 month follow-up visit (T1). (C) Age in years at the time of ART initiation vs. fold
Cihan Tastan (3079533), Tiina Ilmet (3079542), Max Kilberg (3079539), William Borkowsky (591602), Adam Kravietz (3079530), Derya Unutmaz (52436), Mengling Liu (136610), Mussa Mwamzuka (3079536), Aabid Ahmed (3079545), Alka Khaitan (3079527), Fatma Marshed (3079524)   +10 more
core   +1 more source

Estrogen Induced Regulation of Mucosal-Associated Invariant T Cells in Asthma

Journal of Immunology Research
Asthma affects over 300 million people worldwide, with increasing rates annually. Males have higher asthma prevalence in adolescence, while females exhibit higher rates in adulthood. Reduced mucosal-associated invariant T (MAIT) cells are found in severe
Shubhanshi Trivedi, Samuel E. Aamodt, Thomas P. Huecksteadt, Elizabeth J. Myers, Grace Helen McGee, Jackson G. Cacioppo, Jeffrey Aubé, Robert Paine, Daniel T. Leung, Kristi J. Warren   +9 more
doaj   +1 more source

Human MAIT cells have a cytotoxic potential.

, 2013
(A) May-Grunwald Giemsa coloration of sorted MAIT (Vα7.2+CD161hi), CD8 and CD4 memory (CD45RO+) T cells from peripheral blood. Arrows indicates basophilic granules present in the cytoplasm of CD8 memory T cells and MAIT cells.
Emmanuel Martin (95724), David Sleurs (469494), Stéphanie Bessoles (469492), Nacer-Eddine Serriari (469495), Emmanuel Treiner (266383), Claire Hivroz (221755), Mathilde Dusseaux (469491), Philippe Sansonetti (69367), Marie-Lise Gougeon (248350), Virginie Premel (266399), Maxime Coré (469493), Claire Soudais (64699), Armelle Bohineust (221753), Olivier Lantz (46680), Lionel Le Bourhis (60603)   +14 more
core   +1 more source