Results 91 to 100 of about 7,106 (183)

Mucosal-Associated Invariant T Cells in Autoimmune Diseases

Frontiers in Immunology, 2018
Mucosal-associated invariant T (MAIT) cells are innate T cells restricted by MHC-related molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in humans and TRAV1-TRAJ33 in mice.
Asako Chiba, Goh Murayama, Sachiko Miyake   +2 more
doaj   +1 more source

High pre-transplant Mucosal Associated Invariant T Cell (MAIT) count predicts favorable course of myeloid aplasia

Biomedical Papers
Aims. Mucosal Associated Invariant T (MAIT) cells are unconventional T cells with anti-infective potential. MAIT cells detect and fight against microbes on mucosal surfaces and in peripheral tissues.
Ivana Karlova Zubata, Jitka Smetanova Brozova, Tomas Karel, Barbora Bacova, Jan Novak   +4 more
doaj   +1 more source

Mucosal-associated invariant T cells recognize a tumor-derived metabolite in the DNA synthesis pathway

Frontiers in Immunology
Mucosal-associated invariant T (MAIT) cells recognize metabolite-derived ligands, but the identity of such ligands in the context of cancer remains poorly defined.
Yanqi Xue, Yuka Yamada, Rikako Suzuki, Brenda Luong, Shotaro Fujii, Keisuke Nakata, Masatomo Takahashi, Yoshihiro Izumi, Chihiro Fukui, Ryosuke Takasaki, Francois Legoux, Shinsuke Inuki, Shinsuke Inuki, Daisuke Motooka, Emi Ito, Bridget L. Stocker, Mattie S. M. Timmer, Takashi Shimizu, Yasumasa Matsuoka, Jun’ichi Mano, Koji Tamada, Koji Tamada, Makoto Furutani-Seiki, Kei Sakamoto, Koh-Hei Sonoda, Olivier Lantz, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki, Kensuke Shibata, Kensuke Shibata, Kensuke Shibata   +33 more
doaj   +1 more source

MAIT cells in the liver environment

, 2020
MAIT cells are an important innate T cell population capable of recognising riboflavin-derived ligands presented by the evolutionary conserved MR1 molecule. The ability to activate MAIT cells either through their TCR or cytokines alone enables them to respond to both bacterial and viral infections.
openaire   +1 more source

Mucosal-associated invariant T (MAIT) cells are reduced and dysfunctional in acute melioidosis. [PDF]

Sci Rep
Chowdhury FR, Zewdie M, Abraham P, Moulik S, Adebowale H, Hill J, Amin MR, Barai L, Hasan MR, Kurioka A, Rongkard P, Limmathurotsakul D, Day NPJ, Chamnan P, Klenerman P, Willberg CB, Kronsteiner B, Dunachie SJ.   +17 more
europepmc   +2 more sources

Unconventional guardians of the brain: MAIT cells as emerging players in glioblastoma immunity. [PDF]

Front Immunol
Eddy EM, Patton T, Barrow AD, Corbett AJ.   +3 more
europepmc   +1 more source

Avoidance of MAIT cells is an essential determinant of <i>Listeria</i> monocytogenes pathogenesis. [PDF]

Proc Natl Acad Sci U S A
Rivera-Lugo R, Garcia Castillo J, Lobanovska M, Tang E, Anaya-Sanchez A, Espich S, Stanley SA, DuPage M, Portnoy DA.   +8 more
europepmc   +1 more source

Antigenic stimulation in conjunction with cytokine is required for mediating IL-17A production in human MAIT cells. [PDF]

Sci Rep
Kim SJ, Kain D, Lewinsohn DA, Swarbrick GM, Cansler ME, Bimber BN, McElfresh GW, Wong EB, Khuzwayo S, Riffelmacher T, Lewinsohn DM.   +10 more
europepmc   +1 more source

MAIT Cells Maintain Intestinal Homeostasis Through IL-22 in an Experimental Colitis. [PDF]

J Inflamm Res
Peng Y, Zheng C, Wang Y, Huang F, Shao Y, Liu L, Zhao Q.   +6 more
europepmc   +1 more source

MAIT Cells Suppress IgE-Mediated Asthma via IFNγ-Dependent B Cell Regulation. [PDF]

Allergy
Cannata AM, McAlees JW, Hargis JM, Shankar A, Huang S, Divanovic S, Lewkowich IP.   +6 more
europepmc   +1 more source