Results 101 to 110 of about 8,261 (205)

Number of colonic MAIT cell TCRB sequences found, and their overlap with blood MAIT cells.

, 2023
Number of colonic MAIT cell TCRB sequences found, and their overlap with blood MAIT cells.
Donna M. Shows (17334267), James D. Lord (17334270), Andrew J. Konecny (17334264)   +2 more
core   +1 more source

Vascular Immune Remodeling: A CD4+ T Cell–Driven Immune Trajectory Associated With Arterial Stiffness

Aging Cell, Volume 25, Issue 6, June 2026.
This study integrated arterial stiffness with peripheral TCRβ repertoire and single‐cell transcriptomics in adults without cardiovascular disease, revealing a CD4+ T cell–driven “vascular immune remodeling” trajectory distinct from classical immunosenescence: increased TCR diversity, broad expansion of low‐frequency public clones and virus‐associated ...
Yu Miao, Bangwei Chen, Changqing Zeng, Xiaofen Wu, Minglei Yang, Cuntai Zhang, Jianguo Zhang, Yutao Du, Tao Li, Lei Ruan   +9 more
wiley   +1 more source

Role of mucosal-associated invariant T cells dynamics in pathogenesis of Sjögren syndrome

Scientific Reports
Sjögren syndrome (SS) is an autoimmune disease characterized by chronic inflammatory infiltrates in the salivary and lacrimal glands. Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T-cells, predominantly found in mucosal tissues ...
Jeanne Chauffier, Henri Berger de Gallardo, Mathieu F. Chevalier, Aïcha Kante, Marion Lambert, Xavier Cabrol, Elisa Aldersons, Stéphane Mouly, Karine Champion, Blanca Amador-Borrero, Ruxandra Burlacu, William Bigot, Homa Adle-Biassete, Rachid Kaci, Aurélie Selvanadin, Martine Cohen-Solal, Amélie Coudert, Sophie Caillat-Zucman, Damien Sène, Cloé Comarmond   +19 more
doaj   +1 more source

Functions of mucosal associated invariant T cells in eye diseases

Frontiers in Immunology
Mucosal-associated invariant T (MAIT) cells are a unique subset of T cells that recognizes metabolites derived from the vitamin B2 biosynthetic pathway. Since the identification of cognate antigens for MAIT cells, knowledge of the functions of MAIT cells
Chihiro Fukui, Satoshi Yamana, Yanqi Xue, Mariko Shirane, Hiroki Tsutsui, Kenichiro Asahara, Keiko Yoshitomi, Takako Ito, Tantri Lestari, Eiichi Hasegawa, Nobuyo Yawata, Atsunobu Takeda, Koh-Hei Sonoda, Kensuke Shibata, Kensuke Shibata, Kensuke Shibata   +15 more
doaj   +1 more source

T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection

American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett, Ramatoulaye H. Ouattara, April L. Ferre   +2 more
wiley   +1 more source

Potential of MAIT cells to modulate asthma

Allergology International
Despite recent advances in asthma treatments, the search for novel therapies remains necessary because there are still patients with recurrent asthma exacerbations and poor responses to the existing treatments. Since group 2 innate lymphoid cells (ILC2) play a pivotal role in asthma by triggering and exacerbating type 2 inflammation, controlling ILC2s ...
Yasuo Shimizu, Chie Sugimoto, Hiroshi Wakao   +2 more
openaire   +3 more sources

Increased pathogenicity and pro-inflammatory capabilities of mucosal-associated invariant T cells involved in Oral Lichen Planus

BMC Oral Health
Background Mucosal-associated invariant T (MAIT) cells assume pivotal roles in numerous autoimmune inflammatory maladies. However, scant knowledge exists regarding their involvement in the pathological progression of oral lichen planus (OLP).
Siting Chen, Xiaoli Wu, Yinshen Yang, Xiaoheng Xu, Xiaoqin Xiong, Wenxia Meng   +5 more
doaj   +1 more source

MAIT cells in HIV infected and uninfected children.

, 2016
(A) FACS plot showing representative gating to identify CD8 MAIT cells in an HIV- and HIV+ subject. Plot shown is gated on CD8+ T cells. MAIT cells are identified as the Vα7.2+CD161+ population. (B) CD8+ MAIT cells in HIV-, ART-, and ART+ children.
Cihan Tastan (3079533), Tiina Ilmet (3079542), Max Kilberg (3079539), William Borkowsky (591602), Adam Kravietz (3079530), Derya Unutmaz (52436), Mengling Liu (136610), Mussa Mwamzuka (3079536), Aabid Ahmed (3079545), Alka Khaitan (3079527), Fatma Marshed (3079524)   +10 more
core   +1 more source

The Rise and Fall of MAIT Cells with Age

Scandinavian Journal of Immunology, 2014
To the Editor We read with interest the article by Novak et al. recently published in the Scandinavian Journal of Immunology and write in support of their data. The authors describe the profound changes with age of peripheral circulating mucosal associated invariant T (MAIT) cells in a cohort of patients whose samples were obtained post-clinical ...
Walker LJ, Thamalingam H, Klennerman P
openaire   +3 more sources

Characterization of human Mucosal-associated Invariant T (MAIT) cells

, 2019
Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells restricted by the major histocompatibility complex (MHC) class I–like molecule MHC-related protein 1 (MR1).
Fairlie, David P., Godfrey, DI, Chen, Z, Pellicci, DG, Shihan Li, Gherardin, Nicholas A., McCluskey, James, Godfrey, Dale I., Kjer-Nielsen, Lars, Gherardin, NA, Nicholas A. Gherardin, Meehan, BS, Dale I. Godfrey, Corbett, AJ, Kedzierska, Katherine, Chen, Zhenjun, Bronwyn S. Meehan, McCluskey, J, Lars Kjer‐Nielsen, Eckle, Sidonia B. G., Liyen Loh, Fairlie, DP, Sidonia B. G. Eckle, Alexandra J. Corbett, Souter, Michael N.T., Rossjohn, J, Jamie Rossjohn, Eckle, SBG, Corbett, Alexandra J., Zhenjun Chen, Loh, Liyen, Loh, L, Souter, MNT, Katherine Kedzierska, Li, Shihan, Meehan, Bronwyn S., Rossjohn, Jamie, Kjer-Nielsen, L, Daniel G. Pellicci, Michael N.T. Souter, James McCluskey, Pellicci, Daniel G., David P. Fairlie, Li, S, Kedzierska, K   +44 more
core   +1 more source