Results 101 to 110 of about 12,530 (222)
Frontiers in Immunology, 2020 Chronic HIV infection causes systemic immune activation and dysregulation, resulting in the impairment of most T-cell subsets including MAIT cells. Multiple human cohort studies demonstrate MAIT cells are selectively depleted in the peripheral blood and ...
Isaac M. Barber-Axthelm +4 more
doaj +1 more source
Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable +6 more
wiley +1 more source
MAIT Cell Intracellular Cytokine Staining v1 [PDF]
, 2020 This is part 3.5 of the "Study of MAIT Cell Activation in Viral Infections In Vivo" collection of protocols. Collection Abstract: MAIT cells are abundant, highly evolutionarily conserved innate-like lymphocytes expressing a semi-invariant T cell receptor (TCR), which recognizes microbially derived small intermediate molecules from the riboflavin ...
Timothy S C Hinks +7 more
openaire +1 more source
Frontiers in ImmunologyMucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious diseases, and immunotherapy. This review explores their intricate involvement in cancer, from early detection to their dual functions in promoting inflammation and ...
Mesut Yigit +2 more
doaj +1 more source
NKT sejt szubpopulációk és aktiválódás sclerosis multiplexben = NKT cell subsets and activation in patients with multiple sclerosis [PDF]
, 2008 A vese- és agydaganatokban az NKT, valamint egy új, NKT sejtekhez hasonló T sejt, a MAIT sejtek invariáns receptora kimutatható, vagyis a sclerosis multiplex plakkokban észlelt NKT sejt deficiencia nem a központi idegrendszeri immunszabályozásssal függ ...
Gallyas, Ferenc +4 more
core
Optical computing: introduction by the guest editors to the feature in the 1 May 1988 issue [PDF]
, 1988 The feature in the 1 May 1988 issue of Applied Optics includes a collection of papers originally presented at the 1987 Lake Tahoe Topical Meeting on Optical Computing.
Athale, Ravindra A. +2 more
core +1 more source
Immunology, Volume 178, Issue 1, Page 97-108, May 2026.Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng +7 more
wiley +1 more source
Functions of mucosal associated invariant T cells in eye diseases
Frontiers in ImmunologyMucosal-associated invariant T (MAIT) cells are a unique subset of T cells that recognizes metabolites derived from the vitamin B2 biosynthetic pathway. Since the identification of cognate antigens for MAIT cells, knowledge of the functions of MAIT cells
Chihiro Fukui +15 more
doaj +1 more source
The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans [PDF]
, 2016 Non peer ...
Arola, Johanna +7 more
core +1 more source
From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki +2 more
wiley +1 more source