Results 131 to 140 of about 811 (177)

Behavioral thermoregulatory response to maitotoxin in mice

Toxicon, 1998
Many types of marine algal toxins induce marked hypothermic responses in mice. However, it is not known if the thermoregulatory response to these toxins results from dysfunction in the control of core temperature (Tc) or is a coordinated response to lower Tc as occurs with a variety of xenobiotic insults.
C J, Gordon, Y, Yang, J S, Ramsdell
openaire   +2 more sources

Activation of calcium channels by Maitotoxin

1987
Publisher Summary This chapter describes three techniques that enhance the understanding of the action of maitotoxin by using 45Ca2+ to monitor calcium ion flux. The techniques are not new but are adapted for use with viable dispersed anterior pituitary cells in suspension.
I S, Login, A M, Judd, R M, MacLeod
openaire   +2 more sources

Maitotoxin-elicited calcium influx in cultured cells

Biochemical Pharmacology, 1995
William L Padgett, F Gusovsky, J W Daly
exaly   +2 more sources

A feeding study to probe the uptake of Maitotoxin by snapper (Pagrus auratus)

Harmful Algae, 2014
The role of ciguatoxins (CTX) in Ciguatera fish poisoning (CFP) has been investigated previously, but little is known about Maitotoxin (MTX) and whether it plays a significant role in causing human illness.
Gurjeet S Kohli, Gemma Giménez Papiol, Lesley L Rhodes   +2 more
exaly   +2 more sources

ChemInform Abstract: Structure of Maitotoxin

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. MURATA, H. NAOKI, T. IWASHITA, S. MATSUNAGA, M. SASAKI, A. YOKOYAMA, T. YASUMOTO   +6 more
openaire   +1 more source

Modulation of a calcium-activated chloride current by Maitotoxin

Toxicon, 1999
The effect of Maitotoxin (MTX) on the calcium-activated chloride current (ICl-Ca) from Xenopus oocytes was studied, applying the two-electrode voltage clamp technique. MTX increased the current amplitude at all the voltages explored and reduced the time to reach the maximum current level (time to peak). At low toxin concentrations (15 pM), both effects
M, Martínez, C, Salvador, J M, Farias, L, Vaca, L I, Escobar   +4 more
openaire   +2 more sources

Maitotoxin-induced membrane current in neuroblastoma cells

Brain Research, 1987
Maitotoxin (MTX) is a potent marine toxin isolated from the toxic dinoflagellate, Gambierdiscus toxicus. We have examined the possibility of MTX activating calcium channels using cultured neuroblastoma cells (N1E-115). MTX (10 ng/ml) produced a depolarization of the membrane, which was prevented by the removal of Ca2+ from the external medium.
M, Yoshii, A, Tsunoo, Y, Kuroda, C H, Wu, T, Narahashi   +4 more
openaire   +2 more sources

Complete structure of maitotoxin

Pure and Applied Chemistry, 1998
Abstract
openaire   +1 more source

Complete Relative Stereochemistry of Maitotoxin

Journal of the American Chemical Society, 1996
By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relative stereochemistry of the C.1−C.15 portion was elucidated via a two-phase approach:  (1) the synthesis of the eight diastereomers possible for model C ...
Wanjun Zheng, John A. DeMattei, Jiang-Ping Wu, James J.-W. Duan, Laura R. Cook, Hitoshi Oinuma, Yoshito Kishi   +6 more
openaire   +1 more source

Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin

Natural Toxins, 1999
Maitotoxin (MTX), a putative Ca(2+) channel activator produced by the dinoflagellate Gambierdiscus toxicus showed extremely potent hemolytic and ichthyotoxic activities. Hemolysis of 1% mouse blood cell suspension in saline occurred at 15 nM of MTX.
T, Igarashi, S, Aritake, T, Yasumoto
openaire   +2 more sources