Major Histocompatibility Complex Class II Deficiency Beyond Infancy [PDF]
Case Reports in ImmunologyMajor histocompatibility complex class (MHC)-II deficiency is a rare autosomal recessive combined immunodeficiency, accounting for 4.1% of inborn errors of immunity (IEI) cases in North Africa and the Middle East.
Aziza Bachir Kattra +7 more
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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
Cells, 2019 Fascinating about classical major histocompatibility complex (MHC) molecules is their polymorphism. The present study is a review and discussion of the fish MHC situation. The basic pattern of MHC variation in fish is similar to mammals, with MHC class I
Takuya Yamaguchi, Johannes M. Dijkstra
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Exploration of the Conformational Dynamics of Major Histocompatibility Complex Molecules [PDF]
Frontiers in Immunology, 2017 Major histocompatibility complex (MHC) molecules are loaded with a wide variety of self- and non-self-peptides in their binding grooves and present these to T cell receptors (TCRs) in order to activate the adaptive immune system.
Saeko Yanaka, Kenji Sugase
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Identification of new major histocompatibility complex-B haplotypes in chinese broilers [PDF]
Poultry ScienceMHC in chicken demonstrates a great range of variations. This study was conducted to investigate the major histocompatibility complex-B (MHC-B) variability in three representative broiler breeds with large breeding populations in China namely Arbor Acres
Wanqiang Chen, Xiaoxu Jia, Yushi Gao
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Ancient trans-species polymorphism at the Major Histocompatibility Complex in primates [PDF]
eLifeClassical genes within the Major Histocompatibility Complex (MHC) are responsible for peptide presentation to T cells, thus playing a central role in immune defense against pathogens.
Alyssa Lyn Fortier, Jonathan K Pritchard
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Multiple Loci within the major histocompatibility complex confer risk of psoriasis. [PDF]
PLoS Genetics, 2009 Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249 SNPs. The
Bing-Jian Feng +13 more
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EBV lytic proteins BZLF1 and BILF1 inhibit the expression of major histocompatibility complex in Raji cells [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate whether BZLF1 and BILF1 can inhibit the expression of major histocompatibility complex(MHC)molecules in Raji cells during Epstein-Barr virus (EBV) lytic cycle.
ZHENG Hongling, GUO Qingwei, ZHANG Wei, ZHANG Yan, HE Xingbo, YE Bing
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Major histocompatibility complex Class II-based therapy for stroke
Brain Circulation, 2021 This review discusses the potential of major histocompatibility complex (MHC) Class II constructs as stroke therapeutics. We focus on the delivery of MHC Class II construct, DRmQ, as a safe and effective treatment for ischemic stroke.
Bella M Gonzales-Portillo +4 more
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eLife, 2023 Oligodendrocytes and their progenitors upregulate MHC pathways in response to inflammation, but the frequency of this phenotypic change is unknown and the features of these immune oligodendroglia are poorly defined.
Em P Harrington +8 more
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Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]
, 2014 Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair +3 more
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