Results 1 to 10 of about 129,386 (217)

Major histocompatibility complex in Osteichthyes [PDF]

open access: yesJournal of Veterinary Research, 2020
Based on analysis of available genome sequences, five gene lineages of MHC class I molecules (MHC I-U, -Z, -S, -L and -P) and one gene lineage of MHC class II molecules (MHC II-D) have been identified in Osteichthyes.
Stosik Michał   +2 more
doaj   +3 more sources

Major Histocompatibility Complex Class II Deficiency Beyond Infancy [PDF]

open access: yesCase Reports in Immunology
Major histocompatibility complex class (MHC)-II deficiency is a rare autosomal recessive combined immunodeficiency, accounting for 4.1% of inborn errors of immunity (IEI) cases in North Africa and the Middle East.
Aziza Bachir Kattra   +7 more
doaj   +2 more sources

Identification of new major histocompatibility complex-B haplotypes in chinese broilers [PDF]

open access: yesPoultry Science
MHC in chicken demonstrates a great range of variations. This study was conducted to investigate the major histocompatibility complex-B (MHC-B) variability in three representative broiler breeds with large breeding populations in China namely Arbor Acres
Wanqiang Chen, Xiaoxu Jia, Yushi Gao
doaj   +2 more sources

Ancient trans-species polymorphism at the Major Histocompatibility Complex in primates [PDF]

open access: yeseLife
Classical genes within the Major Histocompatibility Complex (MHC) are responsible for peptide presentation to T cells, thus playing a central role in immune defense against pathogens.
Alyssa Lyn Fortier, Jonathan K Pritchard
doaj   +2 more sources

EBV lytic proteins BZLF1 and BILF1 inhibit the expression of major histocompatibility complex in Raji cells [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate whether BZLF1 and BILF1 can inhibit the expression of major histocompatibility complex(MHC)molecules in Raji cells during Epstein-Barr virus (EBV) lytic cycle.
ZHENG Hongling, GUO Qingwei, ZHANG Wei, ZHANG Yan, HE Xingbo, YE Bing
doaj   +1 more source

Major histocompatibility complex Class II-based therapy for stroke

open access: yesBrain Circulation, 2021
This review discusses the potential of major histocompatibility complex (MHC) Class II constructs as stroke therapeutics. We focus on the delivery of MHC Class II construct, DRmQ, as a safe and effective treatment for ischemic stroke.
Bella M Gonzales-Portillo   +4 more
doaj   +1 more source

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis

open access: yeseLife, 2023
Oligodendrocytes and their progenitors upregulate MHC pathways in response to inflammation, but the frequency of this phenotypic change is unknown and the features of these immune oligodendroglia are poorly defined.
Em P Harrington   +8 more
doaj   +1 more source

MergeReference: A Tool for Merging Reference Panels for HLA Imputation [PDF]

open access: yesGenomics & Informatics, 2017
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers.
Seungho Cook, Buhm Han
doaj   +1 more source

MHC class I allele diversity in cynomolgus macaques of Vietnamese origin [PDF]

open access: yesPeerJ, 2019
Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important experimental animal models for carrying out biomedical researches. The results of biomedical experiments strongly depend on the immunogenetic background of animals, especially on
Shuting Huang   +4 more
doaj   +2 more sources

Major Histocompatibility Complex-B haplotype and ovarian graft response

open access: yesPoultry Science, 2023
: Gonadal tissue transfer is considered one of the best methods to preserve genetic variability. Poultry hosts can receive a gonad from a donor of a different genetic background, sustain the growth of this graft, and produce gametes from it ...
Chi Cuong Quach   +5 more
doaj   +1 more source

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