Results 191 to 200 of about 235,574 (356)

m6A‐modified EHD1 controls PD‐L1 endosomal trafficking to modulate immune evasion and immunotherapy responses in lung adenocarcinoma

open access: yesCancer Communications, EarlyView.
Abstract Background Eps15 homology domain (EHD) proteins, including EHD1 to EHD4, play vital roles in tumor progression. In this study, we aimed to investigate which specific EHD proteins, if any, are implicated in tumor immune evasion and immunotherapy response.
Fanglin Tian   +11 more
wiley   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

PIPLOM: prediction of exogenous peptide loading on major histocompatibility complex class I molecules. [PDF]

open access: yesBioinform Adv
Schmidt F   +11 more
europepmc   +1 more source

Genes of the Major Histocompatibility Complex

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1983
Martha C. Zuniga   +17 more
openaire   +3 more sources

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Four Target Resequencing for the Bovine Major Histocompatibility Complex Region. Proof of Concept. [PDF]

open access: yesHLA
Giovambattista G   +7 more
europepmc   +1 more source

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