Abstract Background Eps15 homology domain (EHD) proteins, including EHD1 to EHD4, play vital roles in tumor progression. In this study, we aimed to investigate which specific EHD proteins, if any, are implicated in tumor immune evasion and immunotherapy response.
Fanglin Tian+11 more
wiley +1 more source
Harnessing chimeric antigen receptor macrophages against solid tumors
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang+3 more
wiley +1 more source
PIPLOM: prediction of exogenous peptide loading on major histocompatibility complex class I molecules. [PDF]
Schmidt F+11 more
europepmc +1 more source
Genes of the Major Histocompatibility Complex
Martha C. Zuniga+17 more
openaire +3 more sources
Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens. [PDF]
Susan L. Swain+3 more
openalex +1 more source
A roadmap for T cell receptor-peptide-bound major histocompatibility complex binding prediction by machine learning: glimpse and foresight. [PDF]
Qi F+7 more
europepmc +1 more source
Anti-influenza virus cytotoxic T lymphocytes recognize the three viral polymerases and a nonstructural protein: responsiveness to individual viral antigens is major histocompatibility complex controlled [PDF]
Jack R. Bennink+3 more
openalex +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Four Target Resequencing for the Bovine Major Histocompatibility Complex Region. Proof of Concept. [PDF]
Giovambattista G+7 more
europepmc +1 more source