Results 131 to 140 of about 187,471 (221)

Well Begun Is Half Done: The Impact of Pre-Processing in MALDI Mass Spectrometry Imaging Analysis Applied to a Case Study of Thyroid Nodules

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The discovery of proteomic biomarkers in cancer research can be effectively performed in situ by exploiting Matrix-Assisted Laser Desorption Ionization (MALDI) Mass Spectrometry Imaging (MSI).
Giulia Capitoli, Kirsten C. J. van Abeelen, Isabella Piga, Vincenzo L’Imperio, Marco S. Nobile, Daniela Besozzi, Stefania Galimberti   +6 more
doaj   +1 more source

Visualization of renal rotenone accumulation after oral administration and in situ detection of kidney injury biomarkers via MALDI mass spectrometry imaging

Frontiers in Molecular Biosciences
The examination of drug accumulation within complex biological systems offers valuable insights into the molecular aspects of drug metabolism and toxicity. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is an innovative
Chuckcris P. Tenebro, Neaven Bon Joy M. Marcial, Janine J. Salcepuedes, Josie C. Torrecampo, Rajelle D. Hernandez, John Alfon P. Francisco, Kristine Mae G. Infante, Veronica J. Belardo, Monissa C. Paderes, Rita Grace Y. Alvero, Jonel P. Saludes, Jonel P. Saludes, Jonel P. Saludes, Doralyn S. Dalisay, Doralyn S. Dalisay, Doralyn S. Dalisay   +15 more
doaj   +1 more source

Analysis of the distribution of adenosine and guanosine on fermented soybean cryosections by MALDI-MSI

Food Chemistry
Bioactive compounds in fermented soybeans (Natto) may reduce cardiovascular disease risk because of their relatively high concentration of vitamin K but may also increase purine levels, thereby increasing the risk of gout. To investigate purine distribution, we overcame the challenges associated with plant cryosection quality by using a conductive ...
Alex, Affricano, Tomoko, Fukuuchi, Komei, Kawamoto, Takushi, Yamamoto, Ei-Ichi, Matsuo, Noriko, Yamaoka, Claudio, Medana, Tadafumi, Kawamoto, Daisuke, Saigusa   +8 more
openaire   +2 more sources

Comparison of the Filamentous Fungi Library v4.0 MALDI Biotyper Platform vs MSI-2 performance for identifying filamentous fungi from liquid cultures

Journal of Clinical Microbiology
Correct, rapid, and reliable filamentous fungi identification is crucial for timely diagnosis and therapy. We compared the performance of the FFLv4.0 MALDI Biotyper and MSI-2 to identify filamentous fungi from clinical isolates.
María F. Gonzalez-Lara, Carla M. Román-Montes, Paulette Díaz-Lomelí, Winston Hernández-Ceballos, Lizeth Morales-Camilo, Axel Cervantes-Sánchez, Andrea Cordero-Rangel, Jazmín Tejeda-Olán, Alexandro Bonifaz-Trujillo, Alfredo Ponce-de-León, Areli Martínez-Gamboa   +10 more
doaj   +1 more source

Imaging mass spectrometry approaches for the detection and localisation of drug compounds and small molecules in tissue [PDF]

A crucial and challenging aspect of the drug development process is the requirement to measure the distribution of a pharmaceutical compound and its metabolites in tissue.
Blatherwick, Eleanor Q.
core  

Imaging the distribution of agrochemicals in plants by MALDI-MSI. [PDF]

Pesticides are widely used in agriculture to control weeds, pests and diseases. Successful control is dependent on the compound reaching the target site within the organism after spray or soil application. This is influenced by a range of physiological and environmental factors.
openaire  

Transfert de coloration assisté par MALDI-MSI : proposition d'une approche multimodale pour l'analyse histopathologique

International audienceTransfert de coloration assisté par MALDI-MSI : proposition d'une approche multimodale pour l'analyse ...
Rmouque, Ilias, Wemmert, Cédric
core   +2 more sources

A MALDI-MSI-based approach to characterize the spatial

Global warming and eutrophication of water bodies are driving the increase in cyanobacterial blooms, which produce toxins such as cylindrospermopsin (CYN). This compound has multiple toxic effects, and following CYN exposure, its distribution in the body varies, particularly in organs such as the liver and kidneys, suggesting its potential for ...
Casas Rodríguez, Antonio, Lopez-Vazquez, Cristina Maria, Guzmán Guillén, Remedios, Ayala, Nahum, Cameán Fernández, Ana María, Jos Gallego, Ángeles Mencía, Chicano-Galvez, Eduardo   +6 more
openaire   +1 more source

Spray-Based Application of Matrix to Agar-Based Microbial Samples for Reproducible Sample Adherence in MALDI MSI

Microbial mass spectrometry imaging (MSI) is a powerful tool used to generate biological hypotheses about the roles of metabolites in microbial competition based upon their two-dimensional spatial distribution.
Justin N. Jens (12134194), Daniel J. Breiner (12134197), Vanessa V. Phelan (12134200)   +2 more
core   +1 more source

Roles of FXR in Lipid Biochemistry within Hepatocellular Carcinoma Using MALDI MSI. [PDF]

J Am Soc Mass Spectrom
Bender KJ, Hu Y, Teodoro BR, Zhai CY, Wan YY, Neumann EK.   +5 more
europepmc   +1 more source