Results 151 to 160 of about 4,457 (177)

Recent Technological Developments in MALDI-MSI Based Hair Analysis

2019
Hair is a common piece of trace evidence found at a crime scene, however, often it is not possible to obtain DNA (due to the lack of a follicular root). These hair samples could potentially provide other intelligence, based on the molecular history of an individual that it contains.
Flinders, Bryn, Bassindale, Tom, Heeren, Ron   +2 more
openaire   +2 more sources

Tissue MALDI Mass Spectrometry Imaging (MALDI MSI) of Peptides

2015
Matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a technique to visualize molecular features of tissues based on mass detection. This chapter focuses on MALDI MSI of peptides and provides detailed operational instructions for sample preparation of cryoconserved and formalin-fixed paraffin-embedded (FFPE) tissue ...
Birte, Beine, Hanna C, Diehl, Helmut E, Meyer, Corinna, Henkel   +3 more
openaire   +2 more sources

Efficiency of the dry–wet method for the MALDI‐MSI analysis of latent fingermarks

Journal of Mass Spectrometry, 2013
ABSTRACTMatrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI‐MSI) has proven to be a powerful analytical tool to investigate problems in several fields of life science. A novel application is in the field of forensics, particularly in the analysis of latent fingermarks.
Leesa S, Ferguson, Stuart, Creasey, Rosalind, Wolstenholme, Malcolm R, Clench, Simona, Francese   +4 more
openaire   +2 more sources

Visualization of single-cell lipidomes with MALDI-MSI

Lipids are central to cellular structure, metabolism, and signaling, and yet their distribution within and across cells is highly heterogeneous. Traditional bulk mass spectrometry masks this diversity, whereas single-cell lipidomics can uncover distinct lipid configurations that define cellular states and organize tissues.
Jean Andrea, Maillat, Nika, Goršek, Pavel, Barahtjan, Giovanni, D'Angelo   +3 more
openaire   +2 more sources

Recent Advances in On‐Tissue Chemical Derivatization Strategies for Enhancing MALDI‐MSI

Mass Spectrometry Reviews
ABSTRACT Matrix‐assisted laser desorption/ionization mass spectrometry imaging (MALDI‐MSI) has rapidly advanced in biomedical research, enabling label‐free, untargeted spatial detection of metabolites, lipids, proteins, and glycans in tissue sections. However, challenges such as low ionization efficiency and chemical instability limit
Meng Huang, Xiaoyu Qi, Dafu Zhu, Hao Zhou, Jie Yuan, Danijela Mišić, Marina Soković, Hongxi Xu, Lu Sun, Yang Ye, Jia Liu   +10 more
openaire   +3 more sources

MALDI-MSI zeigt EVAR-induzierte Aortenwandinstabilität

Gefässchirurgie, 2022
Matthias Buerger, Jan Paul Frese, Sebastian Kapahnke, Elena Kaschina, Manuela Sommerfeld, Oliver Klein, Ben Raude, Adrian Mahlmann, Andreas Greiner, Irene Hinterseher   +9 more
openaire   +1 more source

System klasyfikacji danych obrazowania molekularnego MALDI-MSI [PDF]

, 2022
Pendziałek, Paweł, Polańska, Joanna
openaire   +1 more source

The management of haemoglobin interference for the MALDI-MSI analysis of in-vivo thyroid biopsies [PDF]

, 2018
Introduction Fine Needle Aspiration biopsy (FNAB) is the gold standard exam to determine the malignant nature of thyroid nodules[1]. Contamination of FNAB samples with red blood cells is problematic for proteomics analysis, given that large amounts of haemoglobin (Hb) suppress other protein signals[2].
Piga, I, Capitoli, G, Denti, V, Tettamanti, S, Galimberti, S, Magni, F, Pagni, F   +6 more
openaire   +1 more source

A reliable and effective sample preparation protocol of MALDI-TOF-MSI for lipids imaging analysis in hard and dry cereals

Food Chemistry, 2023
Yan-Ping Shi
exaly  

MALDI-MSI analysis of cancer drugs: Significance, advances, and applications

TrAC - Trends in Analytical Chemistry, 2021
Quan He, Cuirong Sun, Yuanjiang Pan
exaly