Results 171 to 180 of about 187,471 (221)

Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI. [PDF]

open access: yesCancer Res Commun
Hartig JP   +15 more
europepmc   +1 more source

Elucidating Gender-Specific Distribution of Imipramine, Chloroquine, and Their Metabolites in Mice Kidney Tissues through AP-MALDI-MSI. [PDF]

open access: yesInt J Mol Sci
Islam MM   +12 more
europepmc   +1 more source

A Matrix Sublimation Device with an Integrated Solvent Nebulizer for MALDI-MSI

open access: yesJournal of the American Society for Mass Spectrometry, 2021
The current matrix deposition methods in MALDI-mass spectrometry imaging (MALDI-MSI) face technical problems related to the inhomogeneous distribution of crystals and the low analyte extraction and cocrystallization efficiency. In this work, an integrated matrix sublimation device with synchronous solvent nebulization was developed for MALDI-MSI ...
Huizhi Li   +4 more
core   +4 more sources

MALDI-MSI of Lipids in Human Skin

open access: yes, 2017
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS) is now a well-established technique for imaging analysis of sectioned biological tissues. One of the growing areas of interest is in the analysis of skin. MALDI-MSI can provide a wealth of information from within sections of skin. This includes information on the distribution of
Philippa J, Hart, Malcolm R, Clench
openaire   +3 more sources
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MALDI-MSI: A potential game changer in forensic sciences

Forensic Science, Medicine, and Pathology
Matrix-assisted laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) is an analytical technique used for the spatial mapping of drugs, explosives, and organic samples, making it a game-changer in Forensic examination. It detects a wide range of biomolecules in their native state without specific tags, antibodies, labels, and dyes.
Asma, Jamshaid   +2 more
exaly   +3 more sources

Comparing DESI-MSI and MALDI-MSI Mediated Spatial Metabolomics and Their Applications in Cancer Studies

open access: yesFrontiers in Oncology, 2022
Metabolic heterogeneity of cancer contributes significantly to its poor treatment outcomes and prognosis. As a result, studies continue to focus on identifying new biomarkers and metabolic vulnerabilities, both of which depend on the understanding of ...
Yong Dai, Tang Donge
exaly   +2 more sources

MALDI‐MSI: Insights Into Plant, Cell and Environment

Plant, Cell & Environment
Summary statement MALDI‐MSI overcomes the homogenization bottleneck of conventional omics by enabling the in situ visualization of metabolites while preserving native tissue architecture. This spatial perspective reveals metabolic heterogeneity, offering key insights into plant environment adaptation mechanisms.
Hua Guo, Ran Wu, Xiaodong Wang
openaire   +2 more sources

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

open access: yesAnalytical and Bioanalytical Chemistry, 2020
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-growing technique for visualization of the spatial distribution of the small molecular and macromolecular biomolecules in tissue sections. Challenges in MALDI-MSI,
Carsten Hopf   +2 more
exaly   +2 more sources

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