Results 71 to 80 of about 93,889 (197)

MALDI‐MSI for the analysis of a 3D tissue‐engineered psoriatic skin model [PDF]

PROTEOMICS, 2016
MALDI‐MS Imaging is a novel label‐free technique that can be used to visualize the changes in multiple mass responses following treatment. Following treatment with proinflammatory cytokine interleukin‐22 (IL‐22), the epidermal differentiation of Labskin, a living skin equivalent (LSE), successfully modeled psoriasis in vitro.
Harvey, Amanda, Day, Rebecca, Cole, Laura M., Bartlett, Maggie, Warwick, John, Bojar, Richard, Smith, David, Cross, Neil, Clench, Malcolm R.   +8 more
openaire   +3 more sources

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Perspectives of High‐Resolution Mass Spectrometry in Soil Science

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Soil biogeochemical research requires specific, sensitive, and accurate methods to identify and quantify organic molecules in order to trace biochemical processes and assess element cycling in complex, heterogenous systems. High‐resolution mass spectrometry (HRMS) has evolved into a transformative tool for unraveling the complex chemical ...
Bruno Glaser, Tobias Bromm, Klaus Kaiser, Arthur Gross, Carsten Simon, Snežana Maletić, Ines Mulder, Oliver J. Lechtenfeld, Sören Thiele‐Bruhn, Ivy Notterpek, Callum Banfield, Michaela A. Dippold   +11 more
wiley   +1 more source

Simultaneous Mapping of Amino Neurotransmitters and Nucleoside Neuromodulators on Brain Tissue Sections by On-Tissue Chemoselective Derivatization and MALDI-MSI

, 2023
Neurotransmitters (NTs) and neuromodulators (NMs) are two of the most important neurochemicals in the brain, and their imbalances in specific brain regions are thought to underlie certain neurological disorders.
Xinxin Liu (534717), Lihua Zhang (22614), Shuai Huang (60512), Xiaozhe Zhang (1472866), Dan Liu (108669), Yukui Zhang (1413592), Xue Shen (2803513)   +6 more
core   +1 more source

Mini Review: Highlight of Recent Advances and Applications of MALDI Mass Spectrometry Imaging in 2024

Analytical Science Advances
Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI‐MSI) is an emerging imaging tool that allows visualisation of hundreds of analytes unbiasedly in a single experiment.
Yuen Tung Ngai, Darren Lau, Parul Mittal, Peter Hoffmann   +3 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

3,4-Dimethoxycinnamic Acid as a Novel Matrix for Enhanced In Situ Detection and Imaging of Low-Molecular-Weight Compounds in Biological Tissues by MALDI-MSI

, 2019
Low-molecular-weight (low-MW) compounds have many essential functions in biological processes, and the molecular imaging of as many low-MW compounds as possible is critical for understanding complex biological processes.
Xiaodong Wang (66801), Yaqin Liu (130304), Xiaoyan Dai (3637549), Huihong Guo (6270374), Manman Han (6270365), Huixin He (1442797), Yawen Zhang (806754), Maomao Zeng (6270371), Jinming Li (128865), Kaidi Qiu (6270368), Yanyan Li (345271), Liang Qin (534599), Yijun Zhou (168788)   +12 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

MALDI-MSI_Processed data

Processed MALDI-MSI ...
Marlon de Haan (17632803)
core   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source