Results 101 to 110 of about 39,650 (248)
Maleimide, N-ethyl-maleimide (NEM), and N-methyl-maleimide (NMM) were identified as potent catalytic inhibitors of purified human topoisomerase IIalpha, whereas the ring-saturated analog succinimide was completely inactive.
Carstensen, Elisabeth V +8 more
core +1 more source
In Situ EPR Studies of Reaction Pathways in Titania Photocatalyst-Promoted Alkylation of Alkenes
In situ EPR spectroscopy at cryogenic temperatures has been used to observe and identify paramagnetic species produced when titania is irradiated in the presence of reactants used in the photocatalytic alkylation of maleimide with t-butyl carboxylic acid
Shona Rhydderch, Russell F. Howe
doaj +1 more source
Rational design of substituted maleimide dyes with tunable fluorescence and solvafluorochromism [PDF]
A series of maleimide derivatives were systematically designed and synthesized with tunable fluorescent properties. The facile modifications herein provide a simple methodology to expand the scope of maleimide-based dyes and also provide insight into the
Huan Yang +13 more
core +1 more source
A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing
The field of clinical surgery frequently encounters challenges related to atypical wound tissue healing, resulting in the development of persistent chronic wounds or aesthetically displeasing scar tissue.
Mingxue Ma (8207934) +5 more
core +1 more source
Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy
Systemic application of Toll‐like receptor 7/8 (TLR7/8) agonists against cancer is severely limited due to uncontrolled immune activation. In this study, a platinum(IV)‐based prodrug strategy is developed for the systemic administration of a TLR7/8 ...
Michael Gutmann +15 more
doaj +1 more source
Therapeutic microbubbles (thMBs) contain drug-filled liposomes linked to microbubbles and targeted to vascular proteins. Upon the application of a destructive ultrasound trigger, drug uptake to tumour is improved.
Nicola Ingram +6 more
doaj +1 more source
Bulk and Surface Properties of Maleimide Copolymers: Effect of Fluorinated Side Chains
We studied the bulk and surface properties of maleimide (MI) copolymers based on three different main chains, poly(ethene-alt-maleimide), poly(styrene-alt-maleimide), and poly(octadecene-alt-maleimide), with two different types of side chains (4-(N ...
Karina Grundke (2407189) +11 more
core +1 more source
THERMALLY CLEAVABLE HYBRID MATERIALS
Thermally cleavable hybrid materials were prepared by the Diels-Alder cycloaddition reaction of poly(vinyl furfural) to N phenylmaleimido-N’-(triethoxysilylpropyl)urea followed by the sol-gel condensation reaction of trietoxysilyl groups with water and ...
Constantin Gaina +2 more
doaj
ABSTRACT Plant virus‐like particles (VLPs) are promising nanotechnology platforms, but their translation requires purification strategies suitable for large‐scale production. Here, we developed a nuclease‐free downstream process for Physalis mottle virus (PhMV) VLPs expressed in Escherichia coli, combining ammonium sulfate precipitation, low‐pH ...
Sean K. Hsu +3 more
wiley +1 more source
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon +3 more
wiley +1 more source

