Results 251 to 260 of about 43,444 (345)

Supplementary Figure 12 from Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability

Shalom D. Goldberg, Tero Satomaa, Olulanu H. Aina, Olli Aitio, Krista Burke, Vadim Dudkin, Brian Geist, Onyi Irrechukwu, Anna‐Liisa Hänninen, Annamari Heiskanen, Jari Helin, Jukka O. Hiltunen, Jacqueline Kinyamu-Akunda, Donna M. Klein, Neeraj Kohli, Titta Kotiranta, Tuula Lähteenmäki, Ritva Niemelä, Virve Pitkänen, Henna Pynnönen, William Rittase, Kristen Wiley, Junguo Zhou, Juhani Saarinen   +23 more
openalex   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, Volume 2, Issue 3, September 2026.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

B(C₆F₅)₃-Catalyzed Chemical Tagging of Bioactive <i>N</i>-Alkylamines through β-Amino C(sp³)-H Functionalization. [PDF]

Org Lett
Chapman M, Dai C, Wang Y, Zhao C, Pham Q, Chatterjee A, Wasa M.   +6 more
europepmc   +1 more source

Supplementary Figure 14 from Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability

Shalom D. Goldberg, Tero Satomaa, Olulanu H. Aina, Olli Aitio, Krista Burke, Vadim Dudkin, Brian Geist, Onyi Irrechukwu, Anna‐Liisa Hänninen, Annamari Heiskanen, Jari Helin, Jukka O. Hiltunen, Jacqueline Kinyamu-Akunda, Donna M. Klein, Neeraj Kohli, Titta Kotiranta, Tuula Lähteenmäki, Ritva Niemelä, Virve Pitkänen, Henna Pynnönen, William Rittase, Kristen Wiley, Junguo Zhou, Juhani Saarinen   +23 more
openalex   +1 more source

Hydration‐Interaction Balance Controls Morphological Landscapes in Peptide‐Polymer Amphiphiles

Macromolecular Theory and Simulations, Volume 35, Issue 5, September 2026.
This study investigates the self‐assembly of diblock oligomeric peptide‐polymer amphiphiles (PPAs) with systematically varied oligo alkyl acrylate tails. Using cryo‐TEM and large‐scale all‐atom molecular dynamics simulations, we elucidate how the balance between hydrophobic dominance and core hydration governs diverse core morphologies.
Sabila K. Pinky, Nicholas Calzadilla, Benjamin P. Allen, Abigail S. Knight, Yaroslava G. Yingling   +4 more
wiley   +1 more source

uPAR-Guided Dendrimer Gel Nanoparticles Reprogram Inflammation to Stabilize Atherosclerotic Plaques. [PDF]

ACS Appl Mater Interfaces
Chuang HY, Kou H, Huang YW, Yang H.
europepmc   +1 more source

Modular Maleimide Synthesis from Ynamides

Thibault Heymans, Loïc Durand-Baudet, Yohann Landrain, Gwilherm Evano   +3 more
openalex   +2 more sources

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao, Honghua Zhang, Jingyu Chen, Ziyu Qian, Ning Zhang, Yihua Zhang, Hui Ye, Jianbing Wu, Zhangjian Huang   +8 more
wiley   +1 more source

A platform to design and optimise fluorogenic scFvs for detection of interleukin 33. [PDF]

Chem Sci
Reese AE, Karmakar U, Restori M, Hermoso MA, Church GM, Kuru E, Vendrell M.   +6 more
europepmc   +1 more source

Therapeutic potential of CMPP, a novel maleimide derivative, in a reserpine-induced mouse model of pain–depression dyad

Lorca Alzoubi, Yousra Bsieso, O Gammoh, Alaa A. A. Aljabali, Bader A. Salameh, Abdelrahim Alqudah, Esam Qnais, Ahmad M. Al-malkawi, Kayed Abu-Safieh   +8 more
openalex   +1 more source