Results 41 to 50 of about 15,343 (225)
The Fermentation of Sodium Malonate as a Means of Differentiating Aerobacter and Escherichia [PDF]
, 1933 Einar Leifson
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Crystal structure of a seven‐substitution mutant of hydroxynitrile lyase from rubber tree
Acta Crystallographica Section F, Volume 81, Issue 9, Page 398-405, September 2025.The crystal structure of HNL6V, a seven‐substitution variant of hydroxynitrile lyase from rubber tree, reveals that engineered mutations designed to mimic the homologous esterase SABP2 shift the catalytic atom positions intermediate between those of the parent enzyme and the target esterase.The α/β‐hydrolase fold superfamily includes esterases and ...
Colin T. Pierce +8 more
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Metabolomic and proteomic stratification of equine osteoarthritis
Equine Veterinary Journal, Volume 57, Issue 5, Page 1204-1218, September 2025.Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson +5 more
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ChemBioChem, Volume 26, Issue 15, August 22, 2025.A unique chemoenzymatic synthesis route toward (S)‐baclofen is presented, which highlights a hydroformylation and biocatalysis step toward the synthesis of such a challenging β‐chiral amino acid. The shown methodology exhibits high conversions and enantiomeric excess and is transferable to other β‐chiral amines and amino acids.
Feodor Belov +6 more
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THE PREPARATION OF DIETHYL MALONIC ESTER. [PDF]
Journal of the American Chemical Society, 1896 n ...
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European Journal of Organic Chemistry, Volume 28, Issue 30, August 19, 2025.Substituted malonic acid half oxyesters reacted with alkylidene malonates in a fast, efficient decarboxylative Michael addition, delivering adducts in high yields. The reaction occurred in bulk solvent, open to air, needing only a weak amine base as an organocatalyst to drive a mechanism involving addition prior to decarboxylation.
Marine Pinaud +4 more
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The Reactions of Ester with Acyl Chloride in the Presence of Aluminum Chloride. V. Reaction Mechanism of the Benzoylation of Diethyl Malonate [PDF]
, 1962 Hiroo Kaneyuki
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The Synthesis of 8-Hydroxy-1-oxaazulan-2-one and Its Derivatives by the Condensation of 3-Bromotropolones with Diethyl Malonate and Ethyl Acetoacetate [PDF]
, 1964 Kahei Takase
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