Results 41 to 50 of about 1,302 (146)

Electrochemical Decarboxylative Hydroxylation for the Sustainable Synthesis of Bempedoic Acid

ChemElectroChem, Volume 13, Issue 6, 17 March 2026.
A sustainable synthesis of bempedoic acid is achieved using electrochemical hydroxylative decarboxylation as the key step. Starting from Meldrum's acid, mild metal‐free alkylation, hydrolysis, and decarboxylation provide the key precursor, which is electrochemically converted to the alcohol intermediate and then hydrolyzed to the final product ...
Pietro Ronco, Antonia Simi, Enrico Lunghi, Federico Della Negra, Beatrice Trucchi, Massimo Verzini, Giuseppe Zanoni   +6 more
wiley   +1 more source

Design and Synthesis of Polyheterocyclic Compounds Containing Pyrazolopyridopyrimidine Nucleus with Antimicrobial Activities

ChemistryOpen
This study reports the design, synthesis, and antibacterial evaluation of a library of novel polyheterocyclic derivatives featuring a unique fused pyrimidopyridopyrazole moiety.
Farag A. El‐Essawy, Mohammad Ahmad Ahmad Odah   +1 more
doaj   +1 more source

Uncovering the Mechanisms of Long-Range Magnetic Order in [Mn(mal)(H₂O)]_n: Insights from Microscopic and Macroscopic Magnetic Analysis

Magnetochemistry
In this study, we investigate the magnetic properties of the molecular compound [Mn(mal)(H2O)]ₙ (mal = dianion of malonic acid) by integrating microscopic and macroscopic characterization, combining unpolarized neutron diffraction and magnetometry ...
Fernando S. Delgado, Laura Cañadillas-Delgado, Juan Rodríguez-Carvajal, Óscar Fabelo, Jorge Pasán   +4 more
doaj   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger, Nika Podlesnik, Francesco Mele, Michael Schnürch   +3 more
wiley   +1 more source

Recent Progress on Giant Molecules: Synthesis, Assembly, and Applications

Chemistry–Methods, Volume 6, Issue 3, March 2026.
Giant molecules are molecules constructed by molecular nanoparticles with precise, rigid structure, have similar structures with small molecules and a large size as macromolecules. In this review, the constituent modules of giant molecules, as well as their synthesis, self‐assembly, applications in various fields and future developing prospect are ...
Haoyu Chen, Shida Hou, Lize Yu, Shuangshuang Wang, Junjie Li, Yishui Zhao, Jing Yan, Yi Yan   +7 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Ligninolytic Enzyme Content of Mushroom Pleurotus ostreatus and Agaricus bisporus Extracts and In Vitro Rumen Fermentation of Fungal Extract‐Treated Wheat Straw

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Mushrooms produce enzymes via the radical apparatus to attack lignin and cellulose and we evaluated extracts from byproducts of Pleurotus ostreatus and Agaricus bisporus in terms of content of ligninolytic enzymes and as sustainable means of enhancing the degradability of forages. The extracts contained ligninolytic enzymes and were used to treat wheat
E. Daniso, M. Spanghero
wiley   +1 more source

Electron Donor–Acceptor Complexes Without Preinstalled Sacrificial Leaving Groups: Applications in Synthesis

Helvetica Chimica Acta, Volume 109, Issue 3, March 2026.
Leaving‐group–free electron donor–acceptor (EDA) complexes have emerged as a practical platform for photocatalyst‐free radical generation under visible light. This review highlights recent advances in coupling and cyclization reactions driven by such EDA complexes, emphasizing their atom‐economical and sustainable feature.
Wenheng Liu, Line Næsborg
wiley   +1 more source

Epilepsy Phenotype and EEG Finding of Rhythmic High‐Amplitude Delta With Superimposed Spikes (RHADS) in Succinate Dehydrogenase Deficiency

JIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Succinate dehydrogenase (SDH) serves a dual function as complex II of the electron transport chain and an enzyme of the tricarboxylic acid cycle. Pathogenic variants in subunits of SDH result in diverse clinical presentations, including typically autosomal recessive neurodegenerative disorders. Biallelic variants in the SDHA subunit most often
Aaron B. Bowen, Chiadika Nwanze, Cesar Alves, Lance Rodan, Anna Lecticia Pinto, Melissa A. Walker, Irina Anselm, Phillip L. Pearl   +7 more
wiley   +1 more source