Results 111 to 120 of about 204,248 (294)

Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults. [PDF]

, 2016
BACKGROUND: Previous research has shown fluid replacement beverages ingested after exercise can affect hydration biomarkers. No specific hydration marker is universally accepted as an ideal rehydration parameter following strenuous exercise.
Brossman, Bradley, Cho, Daniel J., Fridman, Gregory, Holsworth, Ralph E., St Cyr, John, Weidman, Joseph J.   +5 more
core   +2 more sources

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease

Advanced Science, EarlyView.
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian, Zhenmin Le, Xuanqiao Ye, Zimo Wang, Jiuxiao Li, Chenyu Dong, Yetao Shen, Jiazheng Li, Yueping Ren, Xiaoyin Ma, Wei Chen, Qinxiang Zheng   +11 more
wiley   +1 more source

Relationship Between Oxidative Stress and Severity of Diabetic Foot Ulcers Among Patients With Type‐2 Diabetes Mellitus in Japan: A Cross‐Sectional Study

Health Science Reports
Background Delayed healing of diabetic foot ulcers (DFUs) is associated with significant morbidity, and oxidative stress (OS) induced by a diabetic state is considered an essential factor in the development of DFUs.
Amos Tinashe Nyamadzawo, Junko Nishio, Toshiko Ogawa, Shinobu Okada   +3 more
doaj   +1 more source

Rapid Kinetic Fluorogenic Quantification of Malondialdehyde in Ground Beef

Foods
Malondialdehyde (MDA), a mutagenic and carcinogenic compound, is widely studied in the meat industry and lipid peroxidation research due to its implications for food quality and safety.
Keshav Raj Bhandari, Max Wamsley, Bindu Nanduri, Willard E. Collier, Dongmao Zhang   +4 more
doaj   +1 more source

Influence of Intestinal Strangulation Release on Ischemia-reperfusion Injury in Sprague Dawley Rats

The Annals of African Surgery, 2021
Background: In intestinal ischemia, reperfusion towards the injured intestine can cause further injury to the intestine itself and to remote organs. This research aimed to evaluate the influence of intestinal strangulation release (SR) before resection ...
Ahmad Yani, Dorothy Dorothy, Rizky Amaliah   +2 more
doaj  

Sialic acid accelerates the electrophoretic velocity of injured dorsal root ganglion neurons

Neural Regeneration Research, 2015
Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain.
Chen-xu Li, Guo-ying Ma, Min-fang Guo, Ying Liu   +3 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Innovative Metasurface Colorimetric Cell‐on‐a‐Chip Sensor for Continuous, Label‐Free, Non‐Destructive Assessment of Intestinal Barrier Dynamics

Advanced Science, EarlyView.
We developed a real‐time, label‐free, high‐throughput cell‐on‐a‐chip system based on a metasurface plasmon resonance colorimetric sensor (MetaSPRCS) to evaluate intestinal barrier function. This platform enables continuous monitoring of cell adhesion, proliferation, and barrier layer formation, disruption, and repair.
Youqian Chen, Wen Li, Jiaying Feng, Yue Shu, Yihui Yang, Yuyan Wang, Rui Li, Hanlin Zhou, Xinfan Yang, Yuxue Guo, Mingqian Chen, Wenjun Hu, Gang Logan Liu, Liping Huang, Yanan Li   +14 more
wiley   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Correlation of Lipid Peroxidation with Glycated Haemoglobin Levels in Diabetes Mellitus [PDF]

, 2011
Reactive oxygen species are crucial to normal biological processes; they are potentially dangerous and are commonly referred to as prooxidants. The reactive oxygen intermediates can cause direct cellular injury by including lipid and protein peroxidation
Bhat, GP, Varashree, BS
core