Results 261 to 270 of about 180,373 (302)

Malondialdehyde Derivatives in Urine

1988
Malondialdehyde (MDA) excretion in rat urine is responsive to peroxidation of dietary lipids and to factors which increase lipid peroxidation in vivo: vitamin E deficiency and administration of iron, CCI4 or adriamycin. Urinary MDA is also increased by administration of the lipolytic hormones ACTH and epinephrine and by fasting, particularly when the ...
H H, Draper, M, Hadley
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Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels

The Analyst, 2011
Malondialdehyde (MDA) has become a well-established biomarker for oxidative stress. The most commonly used way to determine urinary MDA levels is the thiobarbituric acid (TBA) assay, which suffers from several drawbacks. In this manuscript, we describe a novel derivatization strategy for the highly sensitive and selective fluorescence-based ...
Giera, M., Kloos, D.P., Raaphorst, A., Mayboroda, O.A., Deelder, A.M., Lingeman, H., Niessen, W.M.A.   +6 more
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Effect of malondialdehyde on nitrosamine formation

Food and Cosmetics Toxicology, 1980
Abstract Several aldehydes associated with foodstuffs were investigated for their effect on the formation of N-nitrosodimethylamine and N-nitrosodiethylamine. Whereas glucose, furfural, benzaldehyde and glyoxal had little influence on nitrosamine formation, malondialdehyde, which can be derived from lipids by peroxidation, greatly influenced the ...
T, Kurechi, K, Kikugawa, M, Ozawa
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Ascorbate and malondialdehyde in stroke patients

Irish Journal of Medical Science, 1994
It is believed that free radical formation and subsequent oxidative damage in the form of lipid peroxidation may be a factor in the cerebral damage secondary to the ischaemia of a cerebrovascular accident (CVA). Total serum ascorbate and malondialdehyde (MDA) were measured in 45 patients with CVA on the day of admission to hospital (Time 0) and 48 ...
P C, Sharpe, C, Mulholland, T, Trinick
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Unequivocal demonstration that malondialdehyde is a mutagen

Carcinogenesis, 1983
Malondialdehyde (MDA), a product of lipid peroxidation and prostaglandin biosynthesis, has been reported to be mutagenic and carcinogenic. Recent evidence suggests, however, that strongly mutagenic impurities are generated during the preparation of MDA that may contribute to the observed biological activity.
A K, Basu, L J, Marnett
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Unique promotion of erythrophagocytosis by malondialdehyde

American Journal of Hematology, 1988
AbstractModification of the normal erythrocyte membrane by reagent malondialdehyde (MDA) promotes phagocytosis of red blood cells by human macrophages, a phenomenon previously shown to involve both IgG‐dependent and IgG‐independent mechanisms and to be demonstrable even at micromolar MDA concentrations.
R P, Hebbel, W J, Miller
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Proinflammatory effects of malondialdehyde in lymphocytes

Journal of Leukocyte Biology, 2012
Abstract MDA changed cytokine/chemokines mRNA profiles in lymphocytes; increased cytokines expression is via oxidative stress, p38MAPK, and PKC pathways. Diabetes is an inflammatory disease promoted by alterations in immune cell function.
Somasundaram, Raghavan, Ganesan, Subramaniyam, Narkunaraja, Shanmugam   +2 more
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Distribution and oxidation of malondialdehyde in mice

Prostaglandins, 1985
The in vivo metabolism of malondialdehyde (MDA) by male and female Swiss mice was investigated. Distribution of an i.p. dose of MDA is rapid and uniform throughout the body. Conversion of 14C-labeled MDA to CO2 is complete 4 hours after an i.p. dose of 5 mumol to 200 mumol with no signs of short term toxicity.
L J, Marnett, J, Buck, M A, Tuttle, A K, Basu, A W, Bull   +4 more
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Malondialdehyde, modified lipoproteins, and atherosclerosis

European Heart Journal, 1990
It is likely that identification of the mechanisms releasing malondialdehyde and other peroxidative decomposition products in the arterial wall will provide new insights into the sequence of biochemical and cellular events in the pathogenesis of atherosclerosis and ultimately may lead to development of strategies for the intervention and reduction of ...
M E, Haberland, D, Fong, L, Cheng
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Malondialdehyde formation in stored plasma

Biochemical and Biophysical Research Communications, 1980
Summary The formation of malondialdehyde in plasma during storage was used as an indicator of lipid peroxidation. Malondialdehyde concentrations were measured in plasma stored at 4°C in the presence of various preservative reagents. A rapid rate of formation of malondialdehyde (15.0 ± 14.0 nmol/dl/week) was observed in control plasma preserved with ...
openaire   +2 more sources