Results 61 to 70 of about 204,248 (294)

Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study

open access: yesChinese Journal of Physiology, 2021
This study aimed to assess the effect of Vitamin C on blood pressure (BP), and subsequently on oxidative stress and nitric oxide (NO) release, following the low-intensity exercise in the patients.
Chongchira Boonthongkaew   +5 more
doaj   +1 more source

Development of an analytical method to determine malondialdehyde as an oxidative marker in cryopreserved bovine semen [PDF]

open access: yes, 2015
Frozen sperm is widely used in artificial insemination of cattle as well as other animal species. As a consequence of the freezing and thawing processes of semen, an excess of reactive oxygen species (ROS) are formed.
Nazareno, Mónica Azucena   +3 more
core   +2 more sources

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]

open access: yes, 2017
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin   +15 more
core   +1 more source

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li   +11 more
wiley   +1 more source

The effect of 8 weeks of Whole-Body High-Intensity Interval Training with the consumption of mango leaf extract on the serum levels of oxidative and antioxidant stress in overweight and obese men [PDF]

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery
Introduction: Obesity and overweight is a growing health concern. One of the important factors in obesity-related diseases is oxidative stress and the disruption of the body’s antioxidant system.
Fatemeh Omidali   +2 more
doaj  

Effect of lupeol on testicular lesions induced by cadmium chloride in rats [PDF]

open access: yesAvicenna Journal of Phytomedicine
Objective: Heavy metals and environmental pollutants, such as cadmium chloride, congenital disorders, and certain diseases, can lead to infertility in men.
Parmida Arabkarami   +2 more
doaj   +1 more source

Disulfide‐Bridged Ru Complex–Mediated Photo‐Disulfidptosis for Colorectal Cancer Therapy

open access: yesAdvanced Science, EarlyView.
In this work, a binuclear ruthenium complex, RuSSRu was developed for efficient colorectal cancer (CRC) treatment. The synergistic interaction between disulfidptosis and lysosomal damage‐induced apoptosis induced by RuSSRu amplified tumor cell death. This innovative approach offers a potent therapeutic strategy for CRC.
Simeng He   +8 more
wiley   +1 more source

Effects of light intensity on physiological traits of bamboo (Fargesia denudata) and poplar (Populus cathayana) during leaf senescence

open access: yes浙江大学学报. 农业与生命科学版, 2008
To determine the effects of intensive light environment in subalpine region, Western China, on plant physiological traits during leaf senescence in late growth season, the photosynthetic rates, contents of photosynthetic pigments and soluble proteins of ...
QIAO Yun-zhou   +3 more
doaj   +1 more source

Development of assays for biomarkers of oxidative damage to assess the efficacy of fruit-derived antioxidants : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

open access: yes, 2003
The diet is a very important part of maintaining a healthy lifestyle. Increased consumption of fruits and vegetables is one practice postulated to decrease the incidence of diseases such as cancer, cardiovascular disease and other disorders.
Barnett, Laura Evelyn
core  

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