Results 31 to 40 of about 82,272 (242)
Infectious Agents and Cancer, 2017 BackgroundThere is substantial evidence that a virus homologous to mouse mammary tumor virus (MMTV) may have a role in human breast cancer. The present study indicates that those who developed breast cancer associated with an MMTV-like virus had this ...
Teiko Nartey +8 more
semanticscholar +1 more source
Infectious Agents and Cancer, 2017 Background Multiple oncogenic viruses including, mouse mammary tumor virus, bovine leukemia virus, human papilloma virus, and Epstein Barr virus, have been identified as separate infectious pathogens in human breast cancer. Here we demonstrate that these
James S. Lawson, Wendy K. Glenn
doaj +1 more source
The Role of a Betaretrovirus in Human Breast Cancer: Enveloping a Conundrum
Viruses, 2022 Most of the evidence that a human betaretrovirus (HBRV/HMTV) highly related to mouse mammary tumour virus (MMTV) has an etiological role in breast cancer has been summarized in a recent comprehensive Special Issue of “Viruses” entitled “Human ...
Walter H. Gunzburg, Brian Salmons
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Effect of trypsin on mouse mammary tumor virus [PDF]
Journal of Virology, 1976 Undisrupted mouse mammary tumor virus (MuMTV) derived from the milk of of RIII mice has been analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electron microscopy after treatment with insolubilized trypsin. No alterations were found in viral fine structure by either freeze-etch or negative-stain electron microscopy.
Sheffield, J B +3 more
openaire +2 more sources
Scientific Reports, 2013 Breast cancer is the most frequent malignancy affecting women worldwide. It has been suggested that infection by Epstein Barr Virus (EBV), Mouse Mammary Tumor Virus or a similar virus, MMTV-like virus (MMTV-LV), play a role in the etiology of the disease.
A. Morales-Sánchez +7 more
semanticscholar +1 more source
Molecular Imaging, 2007 Vascular endothelial growth factor (VEGF) is a major inducer of angiogenesis. We generated a transgenic reporter mouse, VEGF-GL, in which an enhanced green fluorescent protein-luciferase fusion protein is expressed under the control of a human VEGF-A ...
Shannon L. Faley +7 more
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Pericentriolar Targeting of the Mouse Mammary Tumor Virus GAG Protein. [PDF]
PLoS ONE, 2015 The Gag protein of the mouse mammary tumor virus (MMTV) is the chief determinant of subcellular targeting. Electron microscopy studies show that MMTV Gag forms capsids within the cytoplasm and assembles as immature particles with MMTV RNA and the Y box ...
Guangzhi Zhang +7 more
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Polyprotein Precursors to Mouse Mammary Tumor Virus Proteins [PDF]
Journal of Virology, 1979 Mouse mammary tumor virus (MMTV) derived from the culture medium of GR cells contained seven proteins, identified as gp55, gp33, p25, pp20, p16, p12, and p10. The major viral phosphoprotein was the 20,000-molecular-weight protein, pp20. Immunoprecipitation of cytoplasmic extracts from pulse-labeled GR cells identified three MMTV
Anderson, S J +3 more
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Targeting collagen XVIII improves the efficiency of ErbB inhibitors in breast cancer models
The Journal of Clinical Investigation, 2023 The tumor extracellular matrix (ECM) critically regulates cancer progression and treatment response. Expression of the basement membrane component collagen XVIII (ColXVIII) is induced in solid tumors, but its involvement in tumorigenesis has remained ...
Raman Devarajan +18 more
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Cell Reports, 2021 Summary: Basal breast cancer is associated with younger age, early relapse, and a high mortality rate. Here, we use unbiased droplet-based single-cell RNA sequencing (RNA-seq) to elucidate the cellular basis of tumor progression during the specification ...
Fátima Valdés-Mora +21 more
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