Results 11 to 20 of about 88,076 (273)
Cryoelectron Microscopy of Mouse Mammary Tumor Virus [PDF]
Journal of Virology, 2004 ABSTRACT Cryoelectron microscopy of Mouse mammary tumor virus , a Betaretrovirus , provided information about glycoprotein structure and core formation. The virions showed the broad range of diameters typical of retroviruses.
Briggs, J. +3 more
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Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis
Viruses, 2010 Mouse mammary tumor virus (MMTV), which was discovered as a milk‑transmitted, infectious cancer-inducing agent in the 1930s, has been used since that time as an animal model for the study of human breast cancer.
Susan R. Ross
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Rapid spread of mouse mammary tumor virus in cultured human breast cells
Retrovirology, 2007 Background The role of mouse mammary tumor virus (MMTV) as a causative agent in human breast carcinogenesis has recently been the subject of renewed interest.
Günzburg Walter H +4 more
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Viruses, 2023 Mouse mammary tumor virus (MMTV) is a betaretrovirus that causes breast cancer in mice. The mouse mammary epithelial cells are the most permissive cells for MMTV, expressing the highest levels of virus upon infection and being the ones later transformed ...
Waqar Ahmad +7 more
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Structure of the Mouse Mammary Tumor Virus: Polypeptides and Glycoproteins [PDF]
Journal of Virology, 1974 The polypeptide and glycoprotein compositions of the mouse mammary tumor virus virion from primary monolayer cultures of BALB/cfC3H mouse mammary tumor cells were studied by polyacrylamide gel electrophoresis by using internal and external labeling and Coomassie blue and periodic acid Schiff (PAS) staining.
Y A, Teramoto +3 more
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Decitabine suppresses tumor growth by activating mouse mammary tumor virus and interferon-β pathways [PDF]
Biomolecules & BiomedicineDecitabine (DAC), a DNA methyltransferase inhibitor (DNMTi), is clinically effective in hematological malignancies such as myelodysplastic syndrome and acute myeloid leukemia, but its precise antineoplastic mechanisms remain incompletely understood ...
Ryan Johnson +9 more
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IFI16/IFI202 blockade suppresses tumor growth through CD8+ T-cell–mediated immunity [PDF]
Breast Cancer ResearchBackground Tumor-associated macrophages (TAMs) are key drivers of immunosuppressive inflammation in the breast cancer microenvironment, promoting tumor progression and resistance to immune checkpoint blockade.
Ga Young Lim +3 more
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Lessons Learned from Mouse Mammary Tumor Virus in Animal Models
ILAR Journal, 2016 Jaquelin P Dudley +2 more
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Characterization of Mammary Tumors Arising from MMTV-PyVT Transgenic Mice
Current Issues in Molecular Biology, 2023 Among genetically engineered mouse models of breast cancer, MMTV-PyVT is a mouse strain in which the oncogenic polyoma virus middle T antigen is driven by the mouse mammary tumor virus promoter. The aim of the present study was to perform morphologic and
Chien-Liang Liu +6 more
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Special Issue “Human Betaretrovirus and Related Diseases”
Viruses, 2022 A betaretrovirus resembling mouse mammary tumor virus (MMTV) was first linked with human breast cancer over 50 years ago [...]
Andrew L. Mason
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