Results 31 to 40 of about 61,923 (187)
Low prevalence of human mammary tumor virus (HMTV) in breast cancer patients from Myanmar
Infectious Agents and Cancer, 2017 Background Human mammary tumor virus (HMTV) is 90–95% homologous to mouse mammary tumor virus (MMTV), one of the causal agents of murine mammary tumors.
Thar Htet San +9 more
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Rapid spread of mouse mammary tumor virus in cultured human breast cells
Retrovirology, 2007 Background The role of mouse mammary tumor virus (MMTV) as a causative agent in human breast carcinogenesis has recently been the subject of renewed interest.
Günzburg Walter H +4 more
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Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis
Viruses, 2010 Mouse mammary tumor virus (MMTV), which was discovered as a milk‑transmitted, infectious cancer-inducing agent in the 1930s, has been used since that time as an animal model for the study of human breast cancer.
Susan R. Ross
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Effect of trypsin on mouse mammary tumor virus [PDF]
Journal of Virology, 1976 Undisrupted mouse mammary tumor virus (MuMTV) derived from the milk of of RIII mice has been analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electron microscopy after treatment with insolubilized trypsin. No alterations were found in viral fine structure by either freeze-etch or negative-stain electron microscopy.
Sheffield, J B +3 more
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Apc mutation enhances PyMT-induced mammary tumorigenesis.
PLoS ONE, 2011 The Adenomatous Polyposis Coli (APC) tumor suppressor gene is silenced by hypermethylation or mutated in up to 70% of human breast cancers. In mouse models, Apc mutation disrupts normal mammary development and predisposes to mammary tumor formation ...
Jenifer R Prosperi +3 more
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Cells, 2013 Tumorigenesis is often described as a result of accumulated mutations that lead to growth advantage and clonal expansion of mutated cells. There is evidence in the literature that cancer cells are influenced by the microenvironment.
Sonia M. Rosenfield, Gilbert H. Smith
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In Vitro Production of Mouse Mammary Tumor Virus in a Mouse Mammary Tumor Ascites Line [PDF]
Proceedings of the National Academy of Sciences, 1973 An ascites line derived from a spontaneous mouse mammary carcinoma produces, on explantation and cultivation in vitro , large amounts of oncornavirus particles. The biochemical, biophysical, and electron microscopic characteristics of the virions are described.
Keydar, J +3 more
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Breast Cancer: Basic and Clinical Research, 2020 Background: Viral cause of sporadic breast cancer (SBC) has been suggested based on the experimental murine model of mammary tumor caused by mouse mammary tumor virus (MMTV), Epstein-Barr virus (EBV), and human papillomavirus (HPV).
Mohammad Al Hamad +9 more
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Infectious Agents and Cancer, 2017 Background Multiple oncogenic viruses including, mouse mammary tumor virus, bovine leukemia virus, human papilloma virus, and Epstein Barr virus, have been identified as separate infectious pathogens in human breast cancer. Here we demonstrate that these
James S. Lawson, Wendy K. Glenn
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A bioluminescence reporter mouse that monitors expression of constitutively active β-catenin. [PDF]
PLoS ONE, 2017 This short technical report describes the generation and characterization of a bioluminescence reporter mouse that is engineered to detect and longitudinally monitor the expression of doxycycline-induced constitutively active β-catenin. The new responder
Maria M Szwarc +5 more
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