Results 91 to 100 of about 601,539 (340)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Joint angle measurement of manipulator and error compensation based on an IMU sensor

The Journal of Engineering, 2019
To detect the joint angle of the manipulator accurately, a measuring method based on an IMU sensor is proposed. The sensor's attitude angles and corresponding rotation matrix are obtained according to the data of three-axis gyroscope and three-axis ...
Tianlin Zhang, Sheng Chen, Guozheng Xu, Chao Wang, Caiming Tan   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Minimal operation region prediction for networked control robotic manipulators subject to time‐varying delays and disturbances

IET Control Theory & Applications
Due to the disturbances and varying latency, a teleoperated robotic manipulator might not comply with the master control commands. Although prior studies on minimising the impact of network latency and disturbances on teleoperated robots were conducted ...
Van Thanh Huynh, Chee Peng Lim, Zoran Najdovski, Dinh Cong Huong, Hieu Trinh   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Behavioral Robotics Approach to Radiation Mapping Using Adaptive Sampling

Applied Sciences
Radiation mapping is a desirable task to automate because of the inherent risks involved and its tedious nature. A novel system was designed to address this by combining various existing technologies, utilizing behavior-based robotics and Bayesian ...
Joel Adams, Brendon Cintas, Nakwon Sung, Anthony Abrahao, Leonel Lagos, Dwayne McDaniel   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Avatarm: Interacting in the Physical Metaverse via Robotics, Diminished Reality, and Haptics

IEEE Access
The Metaverse is a three-dimensional digital space where users interact and communicate through their avatars, creating a sense of presence and immersion.
Bernardo Brogi, Giovanni Cortigiani, Alberto Villani, Nicole D'Aurizio, Domenico Prattichizzo, Tommaso Lisini Baldi   +5 more
doaj   +1 more source

Dynamic Modeling and Simulation of a Rotating Single Link Flexible Robotic Manipulator Subject to Quick Stops [PDF]

, 2014
Single link robotic manipulators are extensively used in industry and research operations. The main design requirement of such manipulators is to minimize link dynamic deflection and its active end vibrations, and obtain high position accuracy during its
Noroozi, Siamak, Dupac, Mihai
core   +1 more source